The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 2,4,5-Triphenylimidazole, is researched, Molecular C21H16N2, CAS is 484-47-9, about An efficient multicomponent synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetrasubstituted imidazoles catalyzed by a magnetic nanoparticle supported Lewis acidic deep eutectic solvent, the main research direction is imidazole preparation green chem ultrasound irradiation; benzil benzaldehyde ammonium acetate multicomponent; aniline benzaldehyde benzil ammonium acetate multicomponent; magnetic nanoparticle Lewis acid deep eutectic solvent catalyst.COA of Formula: C21H16N2.
A mild and highly efficient reaction for the synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetrasubstituted imidazoles I (R = 2-hydroxyphenyl, 2-fluorophenyl, 1H-indol-3-yl, etc.; R1 = H, phenyl) catalyzed by a magnetically supported Lewis acidic deep eutectic solvent on magnetic nanoparticles (LADES@MNP) has been developed via one-pot multicomponent processes under solvent-free sonication. These reactions have good to excellent yields, mild conditions, and work-up simplicity. This method represents a new method for the preparation of 2,4,5-trisubstituted and 1,2,4,5-tetrasubstituted imidazoles I. More importantly, LADES@MNP can be easily recovered by magnetic separation and reused five times without significant loss of catalytic activity.
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Reference:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts