Tag: M.W=200-250

Nitrile is any organic compound with a −C≡N functional group. 20099-89-2, formula is C9H6BrNO, Name is 4-(2-Bromoacetyl)benzonitrile.The prefix cyano- is used interchangeably with the term nitrile in literature. Category: nitriles-buliding-blocks.

Chen, Liwei;Li, Renfu;Wang, Xinli;Wang, Zexin;Lin, Xiang;Yang, Lu;Yao, Yunpeng;Sun, Shitao;Li, Zhenli;Hao, Jinle;Lin, Bin;Chen, Xueyuan;Xie, Lijun research published 《 New Rofecoxib-Based Mechanochromic Luminescent Materials and Investigations on Their Aggregation-Induced Emission, Acidochromism, and LD-Specific Bioimaging》, the research content is summarized as follows. Development of new mechanochromic luminescent (MCL) materials from aggregation-induced emission luminogens (AIEgens) has attracted wide attention due to their potential application in multiple areas. However, rational design and crafting of new MCL materials from the simple AIEgens skeleton is still a big challenge because of the undesirable concentration quenching effect. In this study, we have constructed a new class of MCL materials by adding one Ph as a new rotator and incorporating one pair of electron donor (D) and acceptor (A) into the system of rofecoxib skeleton. This strategy endowed the compounds (Y1-Y8) with tunable emission behavior and some of them with the AIE effect and reversible MCL behavior. These properties may be caused by the highly twisted conformation and loosely mol. packing modes, which were elucidated clearly by analyzing the data of single-crystal X-ray diffraction, powder X-ray diffraction, and differential scanning calorimetry. Further investigation revealed that Y7 displayed acidochromic property due to the protonation of the nitrogen atom. Moreover, Y7, as a typical compound, showed its potential applications in the area of anticounterfeiting, pH sensor, and LD-specific bioimaging.

Category: nitriles-buliding-blocks, 4-(2-Bromoacetyl)benzonitrile, also known as 2-Bromo-4′ -cyanoacetophenone, is a useful research compound. Its molecular formula is C9H6BrNO and its molecular weight is 224.05 g/mol. The purity is usually 95%.
2-Bromo-4′ -cyanoacetophenone can be synthesized from ethylbenzene via aerobic photooxidation using aqueous HBr.
4-(2-Bromoacetyl)benzonitrile is useful for the irreversible inhibitory activity of Glycogen synthase kinase 3 (GSK-3). Phenylhalomethylketones can be used in the study of novel GSK-3 inhibitors., 20099-89-2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitrile is any organic compound with a −C≡N functional group. 1835-49-0, formula is C8F4N2, Name is Tetrafluoroterephthalonitrile.The prefix cyano- is used interchangeably with the term nitrile in literature. Related Products of 1835-49-0.

Abednatanzi, Sara;Gohari Derakhshandeh, Parviz;Dalapati, Sasanka;Veerapandian, Savita K. P.;Froissart, Anne-Claire;Epping, Jan Dirk;Morent, Rino;De Geyter, Nathalie;Van Der Voort, Pascal research published 《 Metal-Free Chemoselective Reduction of Nitroarenes Catalyzed by Covalent Triazine Frameworks: The Role of Embedded Heteroatoms》, the research content is summarized as follows. Development of robust nanoporous covalent triazine frameworks (CTFs) as metal-free catalysts for the green chemoselective reduction of nitroarenes. The turnover frequency was found to be 43.03 h^-1, exceeding activities of the heteroatom-doped carbon nanomaterials by a factor of 30. The XPS and control experiments provided further insights into the nature of active species for prompt catalysis. This report confirmed the importance of quaternary ‘N’ and ‘F’ atom functionalities to create active hydrogen species via charge delocalization as a critical step in improving the catalytic activity.

Related Products of 1835-49-0, Tetrafluoroterephthalonitrile can react with alkyl grignard reagents to form 4-alkyltetraflurorobenzonitriles. It acts as a four electron donor ligand. Tetrafluoroterephthalonitrile can be used to synthesize polymers of intrinsic microporosity. It has been used to study UV rearranged polymers of teh PIM-1 type membrane for the efficient separation of H2 and CO2.
Tetrafluoroterephthalonitrile reacts with alkyl Grignard reagents to form corresponding 4-alkyltetrafluorobenzonitriles. Tetrafluoroterephthalonitrile acts as a four-electron donor ligand and forms tungsten(II)η 2-nitrile complexes.
Tetrafluoroterephthalonitrile is a hydroxyl group-containing organic chemical compound . It has been used in analytical chemistry as a reagent for the determination of peptide binding constants and disulfide bonds. Tetrafluoroterephthalonitrile binds to nucleophilic sites on proteins, such as the pim-1 protein, and can be used to transport other molecules across cell membranes. In addition, it has been used to produce polymers for use in analytical chemistry. This chemical is also able to bind with magnetic particles under constant pressure conditions, which makes it useful for optical sensor applications. , 1835-49-0.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Inorganic compounds containing the −C≡N group are not called nitriles, but cyanides instead.1835-49-0, formula is C8F4N2, Name is Tetrafluoroterephthalonitrile. Though both nitriles and cyanides can be derived from cyanide salts, most nitriles are not nearly as toxic. HPLC of Formula: 1835-49-0.

Almalki, Masaud;Ducinskas, Algirdas;Carbone, Loi C.;Pfeifer, Lukas;Piveteau, Laura;Luo, Weifan;Lim, Ethan;Gaina, Patricia A.;Schouwink, Pascal A.;Zakeeruddin, Shaik M.;Milic, Jovana V.;Gratzel, Michael research published 《 Nanosegregation in arene-perfluoroarene pi-systems for hybrid layered Dion-Jacobson perovskites》, the research content is summarized as follows. Layered hybrid perovskites are based on organic spacers separating hybrid perovskite slabs. We employ arene and perfluoroarene moieties based on 1,4-phenylenedimethylammonium (PDMA) and its perfluorinated analog (F-PDMA) in the assembly of hybrid layered Dion-Jacobson perovskite phases. The resulting materials are investigated by X-ray diffraction, UV-vis absorption, photoluminescence, and solid-state NMR spectroscopy to demonstrate the formation of layered perovskite phases. Moreover, their behavior was probed in humid environments to reveal nanoscale segregation of layered perovskite species based on PDMA and F-PDMA components, along with enhanced stabilities of perfluoroarene systems, which is relevant to their application.

1835-49-0, Tetrafluoroterephthalonitrile can react with alkyl grignard reagents to form 4-alkyltetraflurorobenzonitriles. It acts as a four electron donor ligand. Tetrafluoroterephthalonitrile can be used to synthesize polymers of intrinsic microporosity. It has been used to study UV rearranged polymers of teh PIM-1 type membrane for the efficient separation of H2 and CO2.
Tetrafluoroterephthalonitrile reacts with alkyl Grignard reagents to form corresponding 4-alkyltetrafluorobenzonitriles. Tetrafluoroterephthalonitrile acts as a four-electron donor ligand and forms tungsten(II)η 2-nitrile complexes.
Tetrafluoroterephthalonitrile is a hydroxyl group-containing organic chemical compound . It has been used in analytical chemistry as a reagent for the determination of peptide binding constants and disulfide bonds. Tetrafluoroterephthalonitrile binds to nucleophilic sites on proteins, such as the pim-1 protein, and can be used to transport other molecules across cell membranes. In addition, it has been used to produce polymers for use in analytical chemistry. This chemical is also able to bind with magnetic particles under constant pressure conditions, which makes it useful for optical sensor applications. , HPLC of Formula: 1835-49-0

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitrile is any organic compound with a −C≡N functional group. 20099-89-2, formula is C9H6BrNO, Name is 4-(2-Bromoacetyl)benzonitrile.The prefix cyano- is used interchangeably with the term nitrile in literature. Application of C9H6BrNO.

Al-Matarneh, Maria Cristina;Amarandi, Roxana-Maria;Mangalagiu, Ionel I.;Danac, Ramona research published 《 Synthesis and biological screening of new cyano-substituted pyrrole fused (iso)quinoline derivatives》, the research content is summarized as follows. Several new cyano-substituted derivatives with pyrrolo[1,2-a]quinoline I [R = Br, CN, OMe] and pyrrolo[2,1a]isoquinoline II scaffolds were synthesized by the [3+2] cycloaddition of (iso)quinolinium ylides to fumaronitrile. The cycloimmonium ylides reacted in situ as 1,3-dipoles with fumaronitrile to selectively form distinct final compounds, e.g., III depending on the structure of the (iso)quinolinium salt. Eleven compounds were evaluated for their anticancer activity against a panel of 60 human cancercell lines. The most potent compound III showed a broad spectrum of antiproliferative activity against cancer cell lines representing leukemia, melanoma and cancer of lung, colon, central nervoussystem, ovary, kidney, breast and prostate cancer. In vitro assays and mol. docking revealed tubulin interaction properties of compound III.

Application of C9H6BrNO, 4-(2-Bromoacetyl)benzonitrile, also known as 2-Bromo-4′ -cyanoacetophenone, is a useful research compound. Its molecular formula is C9H6BrNO and its molecular weight is 224.05 g/mol. The purity is usually 95%.
2-Bromo-4′ -cyanoacetophenone can be synthesized from ethylbenzene via aerobic photooxidation using aqueous HBr.
4-(2-Bromoacetyl)benzonitrile is useful for the irreversible inhibitory activity of Glycogen synthase kinase 3 (GSK-3). Phenylhalomethylketones can be used in the study of novel GSK-3 inhibitors., 20099-89-2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Inorganic compounds containing the −C≡N group are not called nitriles, but cyanides instead.1835-49-0, formula is C8F4N2, Name is Tetrafluoroterephthalonitrile. Though both nitriles and cyanides can be derived from cyanide salts, most nitriles are not nearly as toxic. Synthetic Route of 1835-49-0.

Ameen, Ahmed W.;Ji, Jing;Tamaddondar, Marzieh;Moshenpour, Sajjad;Foster, Andrew B.;Fan, Xiaolei;Budd, Peter M.;Mattia, Davide;Gorgojo, Patricia research published 《 2D boron nitride nanosheets in PIM-1 membranes for CO₂/CH₄ separation》, the research content is summarized as follows. Phys. aging represents one of the major obstacles towards adoption of polymer of intrinsic microporosity (PIM) membranes for gas separation applications. In this work, mixed matrix membranes (MMMs) of 2D boron nitride nanosheets (BNNS) and PIM-1 were prepared and applied in the separation of a CO₂/CH₄ (1:1, v:v) binary gas mixture The membranes were tested over a period of more than one year to evaluate their anti-aging properties as compared to neat PIM-1. The results show that introducing BNNS into PIM-1 leads to a significant reduction in the phys. aging of PIM-1, as demonstrated by the values of reduction in CO₂ permeability after 414 days (22% for the MMMs as compared to 58% for neat PIM-1). This work paves the way to using PIM-based membranes in industry.

Synthetic Route of 1835-49-0, Tetrafluoroterephthalonitrile can react with alkyl grignard reagents to form 4-alkyltetraflurorobenzonitriles. It acts as a four electron donor ligand. Tetrafluoroterephthalonitrile can be used to synthesize polymers of intrinsic microporosity. It has been used to study UV rearranged polymers of teh PIM-1 type membrane for the efficient separation of H2 and CO2.
Tetrafluoroterephthalonitrile reacts with alkyl Grignard reagents to form corresponding 4-alkyltetrafluorobenzonitriles. Tetrafluoroterephthalonitrile acts as a four-electron donor ligand and forms tungsten(II)η 2-nitrile complexes.
Tetrafluoroterephthalonitrile is a hydroxyl group-containing organic chemical compound . It has been used in analytical chemistry as a reagent for the determination of peptide binding constants and disulfide bonds. Tetrafluoroterephthalonitrile binds to nucleophilic sites on proteins, such as the pim-1 protein, and can be used to transport other molecules across cell membranes. In addition, it has been used to produce polymers for use in analytical chemistry. This chemical is also able to bind with magnetic particles under constant pressure conditions, which makes it useful for optical sensor applications. , 1835-49-0.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitrile is any organic compound with a −C≡N functional group. 20099-89-2, formula is C9H6BrNO, Name is 4-(2-Bromoacetyl)benzonitrile.The prefix cyano- is used interchangeably with the term nitrile in literature. Reference of 20099-89-2.

Fultariya, Chirag R.;Harsora, Jalpa P. research published 《 Synthesis, antimicrobial activity and cytotoxicity of 2-substituted benzimidazole incorporated with thiazole》, the research content is summarized as follows. Two new series 2-(2-(1-(1-methyl-1H-benzo[d]imidazol-2-yl)ethylidene)hydrazinyl)-4-(aryl)thiazoles I (R = H, 4-CH₃, 2-Cl, etc.) and 2-(2-(1-(1-methyl-1H-benzo[d]imidazol-2-yl)ethyl)hydrazinyl)-4-(aryl)thiazoles II (R =H, 4-CH₃, 2-Cl, etc.) encompassing benzimidazole incorporated with thiazole have been synthesized using rational approach. These thiazole derivatives I have been reduced at the site of formation of Schiff base (>CH = N0) to obtain final compounds II. Compounds I and II have been screened for their in vitro antibacterial and antifungal actions against four strains each. Among the screened compounds, I (R = 2-Cl, 4-Cl, 4-Br, 4-F, 2,4-diCl, 2,4-diF) and II (R = 2-Cl, 4-Cl, 4-Br, 2,4-diF) have emerged as highly effective antibacterial agents, while compounds I (R = 2-Cl, 4-Cl, 4-Br, 2,4-diF) and II (R = 2,4-diF) have come out as most potent antifungal mols. Comparison of outcomes of antibacterial and antifungal screening of compounds I and II directed that antimicrobial potential of unreduced derivatives I is higher than reduced derivatives II. SAR study reveals that presence of halogen (-F, -Cl, -Br) substituents is accountable for significant antimicrobial potential. Also the results of preliminary MTT cytotoxicity assay on HeLa cells indicates that antimicrobial activity of I (R = 4-Cl, 4-Br, 4-F, 2,4-diCl, 2,4-diF) and II (R = 4-Cl, 4-Br, 2,4-diF) is accompanied by low extent of cytotoxic concentrations

Reference of 20099-89-2, 4-(2-Bromoacetyl)benzonitrile, also known as 2-Bromo-4′ -cyanoacetophenone, is a useful research compound. Its molecular formula is C9H6BrNO and its molecular weight is 224.05 g/mol. The purity is usually 95%.
2-Bromo-4′ -cyanoacetophenone can be synthesized from ethylbenzene via aerobic photooxidation using aqueous HBr.
4-(2-Bromoacetyl)benzonitrile is useful for the irreversible inhibitory activity of Glycogen synthase kinase 3 (GSK-3). Phenylhalomethylketones can be used in the study of novel GSK-3 inhibitors., 20099-89-2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts