Tag: M.W=100-150

Cai, Xue published the artcileDimeric phthalocyanine-involved double-decker complex-based electrochemical sensor for simultaneous detection of acetaminophen and ascorbic acid, Application of Phthalonitrile, the main research area is acetaminophen ascorbic acid phthalocyanine double decker complex electrochem sensor.

An electrochem.sensor for simultaneous detection of acetaminophen (APAP) and ascorbic acid (AA) is firstly developed by using the self-assembled film of a novel dimeric bis(phthalocyaninato) europium complex, [{Pc(SC2H5)8}Eu{BiPc(SC2H5)12}Eu{Pc(SC2H5)8}] (1) coated onto ITO (fim-1/ITO) fabricated through a solution-processing quasi-LangmuirShafer (QLS) protocol. A combination of unique sandwich mol.structure with extented π-conjugated system and J-type aggregates with quite uniform nanograins (ca.15 nm) formed on ITO substrate render the film of 1 the excellent charge transfer ability and abundant electroactive sites, resulting in sensitive detection of APAP and AA with the good sensitivities of 254 and 85.6 mA μM-1 cm-2 and low detection limits of 1.3 and 3.7 μM for APAP and AA resp. More importantly, a simultaneous determinationof APAP and AA at a coexisting system of APAP and AA is also achieved with the still good sensitivities of 317 and 64.7 mA μM-1 cm-2, and low detection limits of 1.0 and 4.9 μM for APAP and AA resp. This work represents the first example of tetrapyrrole-based organicsemiconductor electrochem.sensor for simultaneous detection of APAP and AA with excellent sensing performance, implying the great application potential of electroactive sandwich rare earth tetrapyrrole compoundsin the nonenzymic electrochem.sensors.

Journal of Materials Science: Materials in Electronics published new progress about Analysis. 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, Application of Phthalonitrile.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Zhao, Yun-Xiu published the artcileNeonicotinoid thiacloprid transformation by the N2-fixing bacterium Microvirga flocculans CGMCC 1.16731 and toxicity of the amide metabolite, Recommanded Product: Picolinonitrile, the main research area is Microvirga Daphnia neonicotinoid thiacloprid transformation amide metabolite toxicity.

Thiacloprid is a widely-used neonicotinoid insecticide, but its enzymic conversion and the toxicity of the amide metabolite are poorly understood. Here, a N2-fixing bacterium, Microvirga flocculans CGMCC 1.16731, was reported to metabolize thiacloprid via hydration and hydroxylation to thiacloprid amide and 4-hydroxy thiacloprid resp. M. flocculans transformed 90.5% of 0.63 mmol/L thiacloprid in 30 h with a half-life of 9.0 h. In soil, the bacterium transformed 92.4% of 80 μmol/kg soil thiacloprid in 9 d. A cobalt-type nitrile hydratase (NHase) composed of an α-subunit (TnhA) and a β-subunit (TnhB) converted thiacloprid to thiacloprid amide. Co-expression of activator (TnhC) with NHase could improve the TnhA solubility and therefore enhanced 4-folds higher NHase activity. The NHase produced recombinantly in Escherichia coli transformed 97% of 0.76 mmol/L thiacloprid in 10 min. M. flocculans NHase had a Km value of 0.63 mmol/L and Vmax of 10.2 μmol/min/mg toward thiacloprid. Thiacloprid amide has higher toxic effect on growth of M. flocculans than thiacloprid, whereas lower toxic on the aquatic invertebrate Daphnia magna. Both thiacloprid and thiacloprid amide inhibited tnhA transcription. This increases our understanding of the enzymic mechanism of environmental fate of thiacloprid and toxicity of its amide metabolite toward soil microbes and aquatic organisms.

International Biodeterioration & Biodegradation published new progress about Aquation. 100-70-9 belongs to class nitriles-buliding-blocks, name is Picolinonitrile, and the molecular formula is C6H4N2, Recommanded Product: Picolinonitrile.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Manning, Trevor W. published the artcileStructure of an unusual tetracyclic deoxyguanosine adduct: Implications for frameshift mutagenicity of ortho-cyano nitroanilines, Recommanded Product: 2-Aminobenzonitrile(Flakes or Chunks), the main research area is structure tetracyclic deoxyguanosine adduct frameshift mutagenicity orthocyanonitroaniline.

Nitroarom. compounds represent a major class of industrial chems. that are also found in nature. Polycyclic derivatives are regarded as potent mutagens and carcinogens following bioactivation to produce nitrenium electrophiles that covalently modify DNA to afford N-linked C8-2′-deoxyguanosine (C8-dG) lesions that can induce frameshift mutations, especially in CpG repeat sequences. In contrast, their monocyclic counterparts typically exhibit weak mutagenicity or a lack thereof, despite also undergoing bioactivation to afford N-linked C8-dG adducts. Recently, it has been reported that cyano substitution can greatly increase the mutagenicity of nitroaniline derivatives that are components of azo dyes. The basis of this “”cyano effect”” may be rooted in the formation of a novel polycyclic adduct arising from initial formation of the N-linked C8-dG adduct followed by a cyclization process involving N7 of dG and the ortho-CN group of the attached C8-aryl moiety to generate a quinazolinimine ring as part of a fused tetracyclic C8,N7-dG adduct structure. The present work structurally characterizes this novel cyclic adduct using a combination of optical spectroscopies, NMR anal., d. functional theory (DFT) calculations, and mol. dynamics (MD) simulations. Our data indicate that this highly fluorescent cyclic adduct adopts the promutagenic syn conformation and can stabilize the slipped mutagenic intermediate (SMI) within the CpG repeat of the NarI sequence, which is a hotspot for frameshift mutagenesis mediated by polycyclic N-linked C8-dG adducts. In contrast, the open para-CN (4-aminobenzontrile-derived) N-linked C8-dG adduct is less likely to disrupt the canonical B-form. Together, our results provide a rationale for the potent mutagenicity of cyano-substituted nitroaniline derivatives recently reported in frameshift-sensitive tester strains.

Chemical Research in Toxicology published new progress about Azo dyes. 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Recommanded Product: 2-Aminobenzonitrile(Flakes or Chunks).

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Luc, Nhu-Quynh published the artcileDensity Function Theory calculation, and phthalonitrile process for a synthesis of single crystal zinc phthalocyanine, SDS of cas: 91-15-6, the main research area is single crystal zinc phthalocyanine phthalonitrile density function theory.

This study aims to synthesize the β-phase single crystal of zinc phthalocyanine (ZnPc) by using phthalonitrile process and vapor deposition. The single-crystal X-ray diffraction was used to identify the mol. structure and lattice parameters of the synthesized material. The mol. structure, frontier MOs, and IR spectroscopy of ZnPc were investigated through Time Dependent (TD)-D. Function Theory (DFT) calculations that is compared with exptl. results. For the solid-state simulation, the exptl. crystallog. data was used to determine band structure and d. of state using DFT method on Quantum Espresso. The β-phase monoclinic single crystal of ZnPc is as a direct band gap semiconductor with the calculated energy gap of 2.1 eV, and the Fermi energy level of 2.61 eV.

Materials Science in Semiconductor Processing published new progress about Band gap. 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, SDS of cas: 91-15-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Kumar, Deepak published the artcileSyntheses and characterizations of calcium and strontium based coordination compounds with the 5-(2-pyridyl)tetrazolate ligand, respectively exhibiting extended 1 D and 2 D structures, SDS of cas: 100-70-9, the main research area is calcium strontium pyridyltetrazolate complex preparation crystal structure luminescence; thermal stability calcium strontium pyridyltetrazolate complex.

Coordination compounds of calcium and strontium with 5-(2-pyridyl)tetrazolate ligand (2-PTZ) were obtained by the reactions of the resp. metal nitrates with 2-cyanopyridine, 2-cyanoacetamide and sodium azide in aqueous solutions Both the complexes have similar composition i.e. [M(2-PTZ)2(H2O)4]n.2nH2O where M = Ca(II) (1) and Sr(II) (2). The products were characterized by FTIR spectra and single-crystal x-ray diffractions. Their photoluminescences, bandgaps, and thermal properties were studied. Single crystal x-ray diffractions revealed that both 1 and 2 have distorted square anti-prismatic mol. geometries wherein the two 2-PTZ anions act as bidentate ligands by coordinating via their pyridine-N and tetrazole-N atoms. In both the mols. six water mols., of which four acting as monodentate ligands, and the remaining two in the lattices were present. The lattice H2O mols. significantly stabilized the structures through N··H··O hydrogen bonds with the 2-PTZ ligands in the structures. Compound 2 (with around 50% decomposition) shows better thermal stability than calcium-based compound 1(72% decomposition).

Journal of Molecular Structure published new progress about Band gap. 100-70-9 belongs to class nitriles-buliding-blocks, name is Picolinonitrile, and the molecular formula is C6H4N2, SDS of cas: 100-70-9.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Hu, Yong-Xu published the artcileNovel Ir(III) complexes ligated with 2-(2,6-difluoropyridin-3-yl)benzo[d]thiazole for highly efficient OLEDs with mild efficiency roll-off, Quality Control of 100-70-9, the main research area is iridium complex ligated difluoropyridinylbenzothiazole OLED efficiency.

2-Phenylbenzothiazole-based Ir(III) complex [(bt)2Ir(acac)] is a class of typical yellow phosphorescence material, which has been widely used in OLEDs. However, (bt)2Ir(acac) exhibited only mild photoluminescence quantum efficiency (PLQY) of 0.26-0.28. To further improve the luminous efficiency of benzothiazole-based Ir(III) complex and then boost the corresponding electroluminescent performance, (fpbt)2Ir(pic) and (fpbt)2Ir(tftp) were successfully synthesized, where 2-(2,6-difluoropyridin-3-yl)benzo[d]thiazole (fpbt) was applied as C∩N main ligand, and 2-pyridine carboxylic acid (pic), 2-(3-(trifluoromethyl)-1H-1,2,4-triazol-5-yl)pyridine (tftp) acted as different auxiliary ligands. Both (fpbt)2Ir(pic) and (fpbt)2Ir(tftp) presented excellent PLQYs (0.93-0.95) and high thermostability (330-360 °C). The vacuum-deposited devices following the architecture of ITO/TAPC/CBP: dopant/TPBi/Liq/Al demonstrated prominent performances. Of them, (fpbt)2Ir(pic)-doped OLEDs exhibited better efficiencies of 20.6%, 68.8 cd A-1, and 40.8 l m W-1 while maintaining very mild efficiency roll-off. Such outstanding electrophosphorescent performances were further investigated, which was probably attributed to the following factors: (1) high PLQY; (2) good electron mobility; (3) uniform film-forming property.

Dyes and Pigments published new progress about Band gap. 100-70-9 belongs to class nitriles-buliding-blocks, name is Picolinonitrile, and the molecular formula is C6H4N2, Quality Control of 100-70-9.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Li, Jing published the artcilePalladium-Catalyzed Sequential C-H Activation/Amination with Diaziridinone: An Approach to Indoles, COA of Formula: C7H6N2, the main research area is iodostyrene diaziridinone palladium catalyst bond activation amination tandem; indole preparation.

Indoles are an important class of mols. This paper describes an efficient palladium-catalyzed synthesis of indoles from 2-iodostyrenes and di-t-butyldiaziridinone with a simultaneous installation of two C-N bonds. The reaction process likely proceeds through the oxidative insertion of Pd to aryl iodide and subsequent vinyl C-H activation to from a pallada(II)cycle intermediate, which is bisaminated by di-t-butyldiaziridinone to give the indole product.

Organic Letters published new progress about Amination. 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, COA of Formula: C7H6N2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Batori, Sandor published the artcileSynthetic procedure to pyrido[2,1-f][1,2,4]triazinium salt and related compounds, HPLC of Formula: 100-70-9, the main research area is pyridotriazinium perchlorate preparation; amination cyclocondensation reaction pyridinyl ketone amine.

Pyrido[2,1-f][1,2,4]triazinium perchlorates such as I (R = H, Me, Ph, t-Bu, Cl, 4-morpholinyl, Et2N; R1 = Ph, 4-ClC6H4) were prepared using N-aminations of pyridines and cyclocondensation reactions as key steps. I (R = H; R1 = Ph) formed a hydroxydihydropyridotriazinium perchlorate in the presence of water. 3,4-Dihydropyrido[2,1-f][1,2,4]triazinium perchlorates and a pyrimidotriazinium perchlorate were also prepared using similar methods.

Tetrahedron published new progress about Amination. 100-70-9 belongs to class nitriles-buliding-blocks, name is Picolinonitrile, and the molecular formula is C6H4N2, HPLC of Formula: 100-70-9.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Klyamer, Darya published the artcileVanadyl phthalocyanine films and their hybrid structures with Pd nanoparticles: structure and sensing properties, Product Details of C8H4N2, the main research area is vanadyl phthalocyanine film hybrid structure palladium nanoparticle sensing property; ammonia; chemiresistive sensors; hydrogen; palladium nanoparticles; thin films; vanadyl phthalocyanine.

In this work, thin films of vanadyl phthalocyanines (VOPc and VOPcF4) are studied as active layers for the detection of gaseous ammonia and hydrogen. The effect of F-substituents on the structural features of vanadyl phthalocyanine films and their sensor response toward ammonia (10-50 ppm) and hydrogen (100-500 ppm) is investigated by X-ray diffraction (XRD) and chemiresistive methods, resp. It is shown that the sensor response of VOPcF4 films to ammonia is 2-3 times higher than that of VOPc films. By contrast, the sensor response to hydrogen is higher in the case of VOPc films. Apart from this, the hybrid structures of vanadyl phthalocyanine films with Pd nanoparticles deposited on their surface by a chem. vapor deposition method are also tested to reveal the effect of Pd nanoparticles on the sensitivity of VOPc films to hydrogen. Deposition of Pd nanoparticles on the surface of VOPc films leads to the noticeable increase of their sensitivity to hydrogen.

Sensors published new progress about Annealing. 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, Product Details of C8H4N2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Yu, Bor-Yih published the artcileEvaluating the direct CO2 to diethyl carbonate (DEC) process: Rigorous simulation, techno-economical and environmental evaluation, Name: Picolinonitrile, the main research area is cyanopyridine picolinamide annealing diethyl carbonate simulation.

In this work, the plant-wide process to produce di-Et carbonate (DEC) from the direct reaction of CO2 with ethanol, which uses 2-cyanopyridine (2-CP) as an in situ dehydrating agent, is proposed for the first time. Rigorous design, optimization, ability in carbon reduction, techno-economic and feasibility analyses are all performed in this work. The process consists of two sections. The first one is the main section, in which DEC is generated, along with the removal of water using 2-CP to form 2-picolinamide (2-PA). The second one is the regeneration section, where 2-CP is converted back from 2-PA and recycled. Using simulated annealing method, the optimized CO2 reduction rate in the main section is 0.237 (Ton CO2/Ton DEC generated) on an annual basis. We identify that when the regeneration section is operated with a molar ratio of mesitylene to 2-PA being less than 2.05, the overall process can be in net CO2 reduction Under the constraint of 90 % regeneration of 2-CP as reported in available literature, the produced DEC can match the current market price range under 15 % internal rate of return (IRR), if 2-CP can be obtained with a price lower than 2.56 USD/kg (corresponding to DEC price of 1.10 USD/kg and ethanol price of 0.37 USD/kg) to 6.09 USD/kg (corresponding to DEC price of 1.90 USD/kg and ethanol price of 0.56 USD/kg).

Journal of CO2 Utilization published new progress about Annealing. 100-70-9 belongs to class nitriles-buliding-blocks, name is Picolinonitrile, and the molecular formula is C6H4N2, Name: Picolinonitrile.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts