In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 97165-77-0, name is 3,5-Dibromobenzonitrile belongs to nitriles-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. Safety of 3,5-Dibromobenzonitrile
To a round bottom flask was added 20.0 g (77 mmol) of 3,5-dibromobenzonitrile and 13.2 g (77 mmol) of 1-naphthaleneboronic acid,1.8 g (2 mmol) of tetrakistriphenylphosphine palladium {Pd (PPh3) 4}21.2 g (153 mmol) of potassium carbonate,30 mL of water,100 ml of toluene and 100 ml of tetrahydrofuran were added and the mixture was refluxed for 12 hours.After completion of the reaction, the reaction product was separated, and the organic layer was concentrated under reduced pressure.Hexane, and dried to obtain 13.1 g of a white solid having a yield of 55.5%.
The synthetic route of 97165-77-0 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; SFC Ltd.; Ryu Se-jin; Sim So-yeong; Lee Sang-hae; (39 pag.)KR101964677; (2019); B1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts