Shi, Yongjia published the artcileChiral Bidentate Boryl Ligand Enabled Iridium-Catalyzed Enantioselective C(sp3)-H Borylation of Cyclopropanes, HPLC of Formula: 97009-67-1, the main research area is chiral bidentate boryl ligand preparation catalyst iridium borylation cyclopropane; cyclopropanecarboxamide preparation iridium catalyzed enantioselective borylation; crystal structure chiral boryl cyclopropanecarboxamide; mol structure chiral boryl cyclopropanecarboxamide; bioactive Levomilnacipran enantioselective preparation.
The authors herein report an Ir-catalyzed enantioselective C(sp3)-H borylation of cyclopropanecarboxamides using a chiral bidentate boryl ligand for the 1st time. A variety of substrates with α-quaternary C centers could be compatible in this reaction to provide β-borylated products with good to excellent enantioselectivities. Also the borylated products can be used as versatile precursors engaging in stereospecific transformations of C-B bonds, including the synthesis of a bioactive compound Levomilnacipran.
Journal of the American Chemical Society published new progress about Arylation. 97009-67-1 belongs to class nitriles-buliding-blocks, name is 1-(4-Fluorophenyl)cyclopropanecarbonitrile, and the molecular formula is C10H8FN, HPLC of Formula: 97009-67-1.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts