Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 925672-88-4, name is 5-Bromo-2-cyanobenzeneacetonitrile, This compound has unique chemical properties. The synthetic route is as follows., Safety of 5-Bromo-2-cyanobenzeneacetonitrile
1 ,6-Dibromoisoquinolin-3-amine. 4-Bromo-2-(cyanomethyl)benzonitrile(75 g, 339 mmol) was added to 2,2-dichloroacetic acid (150 mL, 339 mmol). The resulting solution was cooled to 0C in an ice-water bath. HBr (27.5 g, 339 mmol) was bubbled through the cold solution until a yellow precipitate crashed out of solution, resulting in a yellow slurry. HBr was bubbled through the slurry for an additional 5 minutes. The solution was allowed to warm to room temperature over 1 hour. The slurry was then cooled to 0C in an ice-water bath and diethyl ether (200 mL) was added. The mixture was stirred for 20 minutes at 5C. The product was recovered as a yellow solid by filtration (42 g, 41 %). LCMS (API-ES) m/z: 303 (M-^H+).
According to the analysis of related databases, 925672-88-4, the application of this compound in the production field has become more and more popular.
Reference:
Patent; AMGEN INC.; WO2009/11871; (2009); A2;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts