Category: 868-54-2

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 868-54-2, name is 2-Aminoprop-1-ene-1,1,3-tricarbonitrile belongs to nitriles-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. Recommanded Product: 868-54-2

A 10% aqueous solution of KOH (5.60 ml, 10 mmol) andbenzyl chloride (1.15 ml, 10 mmol) were added consecutivelyto a stirred solution of of malononitrile dimer 1 (1.32 g,10 mmol) in DMF (20 ml). The mixture was stirred for 4 hat 20C and diluted with an equal volume of H2O. Theformed precipitate was filtered off, washed with H2O,EtOH, and hexane. Yield 1.80g (81%), colorless crystals,mp 140-142 (Et). IR spectrum, , cm-1: 3397-3295(N), 2219 (C?N). 1H NMR spectrum, delta, ppm (J, Hz):3.21 (1, dd, J = 7.8, J = 13.4) and 3.33 (1, dd, J = 8.6,J = 13.4, 2Ph); 4.18 (1, t, J = 8.0, CHCN); 7.27-7.36(5, m, H Ph); 8.80 (1, br. s) and 9.03 (1, br. s, NH2).Mass spectrum, m/z (Irel, %): 221 [M-]+ (100). Found, %:C 70.33; H 4.58; N 25.09. C13H10N4. Calculated, %:C 70.26; H 4.54; N 25.21.

The synthetic route of 868-54-2 has been constantly updated, and we look forward to future research findings.

Application of 868-54-2, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 868-54-2, name is 2-Aminoprop-1-ene-1,1,3-tricarbonitrile belongs to nitriles-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.

General procedure: Heterocyclic ketene aminals (1 mmol), aryl aldehydes (1.2 mmol), malononitriledimer (1.5 mmol), acetic acid (1 mmol), piperidine (1 mmol) and ethanol (10 mL)were stirred at refluxing for 1 h. After completion of the reaction (confirmed by TLC),the reaction mixture was filtered to afford the crude product, which was furtherwashed with 95% ethanol to give pure product 4.

The synthetic route of 2-Aminoprop-1-ene-1,1,3-tricarbonitrile has been constantly updated, and we look forward to future research findings.

Adding a certain compound to certain chemical reactions, such as: 868-54-2, name is 2-Aminoprop-1-ene-1,1,3-tricarbonitrile, belongs to nitriles-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 868-54-2, name: 2-Aminoprop-1-ene-1,1,3-tricarbonitrile

General procedure: Et3N (0.3 mmol) was added to a stirred solution of salicylaldehyde (3 mmol), 2-aminoprop-1-ene-1,1,3-tricarbonitrile (3 mmol) and 3-trifluoromethyl-2-pyrazolin-5-one in 5 ml of n-PrOH at ambient temperature. Then mixture was refluxed for 4 h. After the reaction was finished and cooled the solid was filtered and dried to isolate pure substituted 2,4-diamino-5-(5-hydroxy-3-(trifluoromethyl)-1H-pyrazol-4-yl)-5H-chromeno[2,3-b]pyridine-3-carbonitrile. In some cases cristallisation from EtOH-DMSO is needed.

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it.

Reference:
Article; Elinson, Michail N.; Vereshchagin, Anatoly N.; Anisina, Yuliya E.; Fakhrutdinov, Artem N.; Goloveshkin, Alexander S.; Egorov, Mikhail P.; Journal of Fluorine Chemistry; vol. 213; (2018); p. 31 – 36;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Adding a certain compound to certain chemical reactions, such as: 868-54-2, name is 2-Aminoprop-1-ene-1,1,3-tricarbonitrile, belongs to nitriles-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 868-54-2, name: 2-Aminoprop-1-ene-1,1,3-tricarbonitrile

General procedure: In a 20 mL reaction vial, 4-hydroxycarbazole 1{1} (0.183g, 1mmol) with benzaldehyde 2{1} (0.106g, 1mmol), and 2-aminoprop-1-ene-1,1,3-tricarbonitrile 3 (0.132g, 1mmol) and ethanol (3 mL), as well as EtONa (0.064g, 1mmol)were mixed and then capped (the automatic mode stirring helped the mixing and uniform heating of the reactants). The mixture was heated for 15 min at 80 C under microwave irradiation. Upon completion, confirmed by TLC, the reaction mixture was cooled to room temperature. The crystalline solid product was collected by Buchner filtration, subsequently washed with two different solvents of ethanol and ethylether in sequence to give the pure product 4{1,1}.

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it.

Reference:
Article; Zhang, Wenhui; Wang, Jianqiang; Mao, Jingpeng; Hu, Li; Wu, Xiaohua; Guo, Cheng; Tetrahedron Letters; vol. 57; 18; (2016); p. 1985 – 1989;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Synthetic Route of 868-54-2,Some common heterocyclic compound, 868-54-2, name is 2-Aminoprop-1-ene-1,1,3-tricarbonitrile, molecular formula is C6H4N4, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

General procedure: Heterocyclic ketene aminals (1 mmol), aryl aldehydes (1.2 mmol), malononitriledimer (1.5 mmol), acetic acid (1 mmol), piperidine (1 mmol) and ethanol (10 mL)were stirred at refluxing for 1 h. After completion of the reaction (confirmed by TLC),the reaction mixture was filtered to afford the crude product, which was furtherwashed with 95% ethanol to give pure product 4.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 2-Aminoprop-1-ene-1,1,3-tricarbonitrile, its application will become more common.

Reference:
Article; Sun, Feilong; Zhu, Fengjuan; Shao, Xusheng; Li, Zhong; Synlett; vol. 26; 16; (2015); p. 2306 – 2312;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 868-54-2, name is 2-Aminoprop-1-ene-1,1,3-tricarbonitrile, This compound has unique chemical properties. The synthetic route is as follows., COA of Formula: C6H4N4

General procedure: Et3N (0.3 mmol) was added to a stirred solution of salicylaldehyde (3 mmol), 2-aminoprop-1-ene-1,1,3-tricarbonitrile (3 mmol) and 3-trifluoromethyl-2-pyrazolin-5-one in 5 ml of n-PrOH at ambient temperature. Then mixture was refluxed for 4 h. After the reaction was finished and cooled the solid was filtered and dried to isolate pure substituted 2,4-diamino-5-(5-hydroxy-3-(trifluoromethyl)-1H-pyrazol-4-yl)-5H-chromeno[2,3-b]pyridine-3-carbonitrile. In some cases cristallisation from EtOH-DMSO is needed.

According to the analysis of related databases, 868-54-2, the application of this compound in the production field has become more and more popular.

Reference:
Article; Elinson, Michail N.; Vereshchagin, Anatoly N.; Anisina, Yuliya E.; Fakhrutdinov, Artem N.; Goloveshkin, Alexander S.; Egorov, Mikhail P.; Journal of Fluorine Chemistry; vol. 213; (2018); p. 31 – 36;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Application of 868-54-2,Some common heterocyclic compound, 868-54-2, name is 2-Aminoprop-1-ene-1,1,3-tricarbonitrile, molecular formula is C6H4N4, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

General procedure: Heterocyclic ketene aminals (1 mmol), aryl aldehydes (1.2 mmol), malononitriledimer (1.5 mmol), acetic acid (1 mmol), piperidine (1 mmol) and ethanol (10 mL)were stirred at refluxing for 1 h. After completion of the reaction (confirmed by TLC),the reaction mixture was filtered to afford the crude product, which was furtherwashed with 95% ethanol to give pure product 4.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 2-Aminoprop-1-ene-1,1,3-tricarbonitrile, its application will become more common.

Reference:
Article; Sun, Feilong; Zhu, Fengjuan; Shao, Xusheng; Li, Zhong; Synlett; vol. 26; 16; (2015); p. 2306 – 2312;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts