Category: 68569-14-2

Lubov, Dmitry P. published the artcilePalladium-Aminopyridine Catalyzed C-H Oxygenation: Probing the Nature of Metal Based Oxidant, HPLC of Formula: 68569-14-2, the publication is ChemCatChem (2021), 13(24), 5109-5120, database is CAplus.

A mechanistic study of direct selective oxidation of benzylic C(sp³)-H groups with peracetic acid, catalyzed by palladium complexes with tripodal amino-tris(pyriylmethyl) ligands, is presented. The oxidation of arylalkanes having secondary and tertiary benzylic C-H groups, predominantly yields, depending on the substrate and conditions, either the corresponding ketones or alcs. One of the three 2-pyridylmethyl moieties, which is pending in the starting catalyst, apparently, facilitates the active species formation and takes part in stabilization of the high-valent Pd center in the active species, occupying the axial coordination site of palladium. The catalytic, as well as isotopic labeling experiments, in combination with ESI-MS data and DFT calculations, point out palladium oxyl species as possible catalytically active sites, operating essentially via C-H abstraction/oxygen rebound pathway. For the ketones formation, O-H abstraction/β-scission mechanism has been proposed.

ChemCatChem published new progress about 68569-14-2. 68569-14-2 belongs to nitriles-buliding-blocks, auxiliary class Palladium, name is Tetrakis(acetonitrile)palladium(II) Ditriflate, and the molecular formula is C10H12F6N4O6PdS2, HPLC of Formula: 68569-14-2.

Referemce:
https://en.wikipedia.org/wiki/Nitrile,
Nitriles – Chemistry LibreTexts

Walker, Sarah E. published the artcileLigand- and Base-Free Pd(II)-Catalyzed Controlled Switching between Oxidative Heck and Conjugate Addition Reactions, COA of Formula: C10H12F6N4O6PdS2, the publication is Organic Letters (2013), 15(8), 1886-1889, database is CAplus and MEDLINE.

A simple change of solvent allows controlled and efficient switching between oxidative Heck and conjugate addition reactions on cyclic Michael acceptor substrates, catalyzed by a cationic Pd(II) catalyst system. E.g., in presence of Pd(OAc)₂ and TfOH in ClCH₂CH₂Cl, reaction of 2-cyclohexenone and tris(4-methoxyphenyl)boroxin gave 94% conjugate addition product I. On the other hand, the same reaction conducted in DMSO gave 84% oxidative Heck reaction product II. Both reactions are ligand- and base-free and tolerant of air and moisture, and the controlled switching sheds light on some of the factors which favor one reaction over the other.

Organic Letters published new progress about 68569-14-2. 68569-14-2 belongs to nitriles-buliding-blocks, auxiliary class Palladium, name is Tetrakis(acetonitrile)palladium(II) Ditriflate, and the molecular formula is C9H21NO3, COA of Formula: C10H12F6N4O6PdS2.

Referemce:
https://en.wikipedia.org/wiki/Nitrile,
Nitriles – Chemistry LibreTexts

Johansson, Maria H. published the artcileThe influence of metal coordination on ligand geometry: the structure of 2-(diphenylphosphino)acetophenone and bis(2-(diphenylphosphino)acetophenone)palladium(II) bistriflate, Safety of Tetrakis(acetonitrile)palladium(II) Ditriflate, the publication is Journal of Molecular Structure (2002), 606(1-3), 51-59, database is CAplus.

The structures of 2(diphenylphosphino)acetophenone and bis(2(di-Ph phosphino)acetophenone)palladium(II) bistriflate were determined by x-ray crystallog. The ligand is of interest because its P,O donor set combines the hard and soft properties. In the Pd-complex, which was prepared by treating tetrakisacetonitrile-Pd-bistriflate with 2-(diphenylphosphino)acetophenone in CH₂Cl₂ for 4 h at room temperature, the O-coordination provides a masked coordinative unsaturation The ligand crystallizes in the monoclinic space group P2₁/c with a 11.050(2), b 16.052(3), c 9.7082(19) Å, β 109.58(3)°, Z = 4. The Pd-complex crystallizes in the orthorhombic space group P2₁2₁2₁ with a 11.867(2), b 18.162(4), c 19.603(4) Å, Z = 4. Both structures were solved by direct methods and the refinements resulted in the R-values of 0.059 and 0.043, for the organic compound and the Pd compound, resp. Two bi-dentate ligand binds to Pd(II) in a cis-configuration. At. coordinates are given. The Pd-O distances are 2.060(3) and 2.096(2) A and the Pd-P distances 2.2290(10) and 2.2294(10) A, showing a large trans-influence of the P atoms. Half-normal probability plot analyses indicate that the s.u.’s are largely underestimated in the studied structures. The bond-angles around the P atom and the orientation of the keto-substituted Ph rings as well as the orientation of the keto-groups are highly affected by metal complexation.

Journal of Molecular Structure published new progress about 68569-14-2. 68569-14-2 belongs to nitriles-buliding-blocks, auxiliary class Palladium, name is Tetrakis(acetonitrile)palladium(II) Ditriflate, and the molecular formula is C10H12F6N4O6PdS2, Safety of Tetrakis(acetonitrile)palladium(II) Ditriflate.

Referemce:
https://en.wikipedia.org/wiki/Nitrile,
Nitriles – Chemistry LibreTexts

Leal, Raul A. published the artcileApplication of a Palladium-Catalyzed C-H Functionalization/Indolization Method to Syntheses of cis-Trikentrin A and Herbindole B, Application In Synthesis of 68569-14-2, the publication is Angewandte Chemie, International Edition (2016), 55(39), 11824-11828, database is CAplus and MEDLINE.

We describe herein formal syntheses of the indole alkaloids cis-trikentrin A, I, and herbindole B, II, from a common meso-hydroquinone intermediate prepared by a ruthenium-catalyzed [2+2+1+1]-cycloaddition that has not been used previously in natural product synthesis. Key steps include a sterically demanding Buchwald-Hartwig amination as well as a unique C(sp³)-H amination/indole formation. Studies toward a selective desymmetrization of the meso-hydroquinone are also reported.

Angewandte Chemie, International Edition published new progress about 68569-14-2. 68569-14-2 belongs to nitriles-buliding-blocks, auxiliary class Palladium, name is Tetrakis(acetonitrile)palladium(II) Ditriflate, and the molecular formula is C10H12F6N4O6PdS2, Application In Synthesis of 68569-14-2.

Referemce:
https://en.wikipedia.org/wiki/Nitrile,
Nitriles – Chemistry LibreTexts

Tang, Jie published the artcileCatalytic Decarboxylative Cross-Coupling of Aryl Chlorides and Benzoates without Activating ortho Substituents, Category: nitriles-buliding-blocks, the publication is Angewandte Chemie, International Edition (2015), 54(44), 13130-13133, database is CAplus and MEDLINE.

The restriction of decarboxylative cross-coupling reactions to ortho-substituted or heterocyclic carboxylate substrates was overcome by holistic optimization of a bimetallic Cu/Pd catalyst system. The combination of a CuI/Me₄phen decarboxylation catalyst and a [(MeCN)₄Pd](OTf)₂/XPhos cross-coupling catalyst enables the synthesis of biaryls from inexpensive aryl chlorides and potassium benzoates regardless of their substitution pattern.

Angewandte Chemie, International Edition published new progress about 68569-14-2. 68569-14-2 belongs to nitriles-buliding-blocks, auxiliary class Palladium, name is Tetrakis(acetonitrile)palladium(II) Ditriflate, and the molecular formula is C4H6N2, Category: nitriles-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Nitrile,
Nitriles – Chemistry LibreTexts