Category: 623-00-7

In 2019,Chem included an article by Li, Jiesheng; Luo, Yixin; Cheo, Han Wen; Lan, Yu; Wu, Jie. Name: 4-Bromobenzonitrile. The article was titled 《Photoredox-Catalysis-Modulated, Nickel-Catalyzed Divergent Difunctionalization of Ethylene》. The information in the text is summarized as follows:

Herein, the use of ethylene feedstock and com. available aryl halides was demonstrated to accomplish the divergent synthesis of 1,2-diarylethanes, 1,4-diarylbutanes, or 2,3-diarylbutanes in a highly selective fashion through the synergistic combination of nickel and photoredox catalysis. Mechanistic studies suggested that the observed selectivity was due to different active states of Ni(I) and Ni(0) modulated by Ru- and Ir-based photoredox catalysts, resp. The ability to access different organometallic oxidation states via photoredox catalysis promises to inspire new perspectives for synergistic transition-metal-catalyzed divergent synthesis. In the experimental materials used by the author, we found 4-Bromobenzonitrile(cas: 623-00-7Name: 4-Bromobenzonitrile)

4-Bromobenzonitrile(cas: 623-00-7) is classified as organic nitriles, which are commonly use solvents and are reacted further for various applications such as manufacture of polymers and intermediates for pharmaceuticals and other organic chemicals,Name: 4-Bromobenzonitrile It can also be used as an aryl halide test compound in developing greener reaction conditions for Suzuki cross-coupling between aryl halides and phenyl boronic acid.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

The author of 《Merging Photoredox PCET with Ni-Catalyzed Cross-Coupling: Cascade Amidoarylation of Unactivated Olefins》 were Zheng, Shuai; Gutierrez-Bonet, Alvaro; Molander, Gary A.. And the article was published in Chem in 2019. Category: nitriles-buliding-blocks The author mentioned the following in the article:

Herein, the amidoarylation of unactivated olefins by a cascade process from non-functionalized amides is reported by merging, for the first time, photoredox proton-coupled electron transfer (PCET) with nickel catalysis. This new technol. grants access to an array of complex mols. containing a privileged pyrrolidinone core from alkenyl amides and aryl- and heteroaryl halides in the presence of a visible light photocatalyst and a nickel catalyst. Notably, the reaction is not restricted to amides-carbamates and ureas can also be used. Mechanistic studies, including hydrogen-bond affinity constants, cyclization rate measurements, quenching studies, and cyclic voltammetry, were central to comprehend the subtleties contributing to the integration of the two catalytic cycles. In addition to this study using 4-Bromobenzonitrile, there are many other studies that have used 4-Bromobenzonitrile(cas: 623-00-7Category: nitriles-buliding-blocks) was used in this study.

4-Bromobenzonitrile(cas: 623-00-7) has been used in the synthesis of 4-iodobenzonitrile via photo-induced aromatic Finkelstein iodination reaction.Category: nitriles-buliding-blocks It can also be used as an aryl halide test compound in developing greener reaction conditions for Suzuki cross-coupling between aryl halides and phenyl boronic acid.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

In 2019,Tetrahedron included an article by Uchida, Ko; Togo, Hideo. Computed Properties of C7H4BrN. The article was titled 《Transformation of aromatic bromides into aromatic nitriles with n-BuLi, pivalonitrile and iodine under metal cyanide-free conditions》. The information in the text is summarized as follows:

Various aromatic nitriles ArCN [Ar = Ph, 4-BrC6H4, 5-ethyl-2-furyl, etc.] were obtained in good yields by the treatment of aryl bromides with n-butyllithium and then pivalonitrile, followed by the treatment with mol. iodine at 70 °C, without metal cyanides under transition-metal-free conditions. The present reaction proceeded through the radical β-elimination of imino-nitrogen-centered radicals formed from the reactions of imines and N-iodoimines under warming conditions. The results came from multiple reactions, including the reaction of 4-Bromobenzonitrile(cas: 623-00-7Computed Properties of C7H4BrN)

4-Bromobenzonitrile(cas: 623-00-7) is classified as organic nitriles, which are commonly use solvents and are reacted further for various applications such as manufacture of polymers and intermediates for pharmaceuticals and other organic chemicals,Computed Properties of C7H4BrN It can also be used as an aryl halide test compound in developing greener reaction conditions for Suzuki cross-coupling between aryl halides and phenyl boronic acid.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

The author of 《Nickel-Catalyzed Electrochemical Phosphorylation of Aryl Bromides》 were Bai, Ya; Liu, Nian; Wang, Shutao; Wang, Siyu; Ning, Shulin; Shi, Lingling; Cui, Lili; Zhang, Zhuoqi; Xiang, Jinbao. And the article was published in Organic Letters in 2019. Formula: C7H4BrN The author mentioned the following in the article:

A nickel-catalyzed electrochem. cross-coupling reaction of aryl bromides with dialkyl phosphites, Et phenylphosphinate, and diphenylphosphine oxide has been developed. This reaction utilizes a simple undivided cell with inexpensive carbon electrodes to synthesize aryl phosphonates, aryl phosphinates, and arylphosphine oxides at room temperature This protocol provides a mild and efficient route for the construction of C-P bond in moderate to high yields with broad substrate scope. In the experiment, the researchers used many compounds, for example, 4-Bromobenzonitrile(cas: 623-00-7Formula: C7H4BrN)

4-Bromobenzonitrile(cas: 623-00-7) has been used in the synthesis of 4-iodobenzonitrile via photo-induced aromatic Finkelstein iodination reaction.Formula: C7H4BrN It can also be used as an aryl halide test compound in developing greener reaction conditions for Suzuki cross-coupling between aryl halides and phenyl boronic acid.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

The author of 《Efficient cyanation of aryl halides with K4[Fe(CN)6] catalyzed by encapsulated palladium nanoparticles in biguanidine-chitosan matrix as core-shell recyclable heterogeneous nanocatalyst》 were Veisi, Hojat. And the article was published in Polyhedron in 2019. SDS of cas: 623-00-7 The author mentioned the following in the article:

Palladium nanoparticles encapsulated in biguanidine-functionalized chitosan matrix (Pd@CS-biguanidine) was applied as a reusable and core-shell nanocatalyst for cyanation of aryl iodides and bromides with K4[Fe(CN)6] as the cyanating agent. The nitriles were generated in good to excellent yield and the catalyst can be recycled and reapplied up to seven times with no significant change in its catalytic performance. The experimental process involved the reaction of 4-Bromobenzonitrile(cas: 623-00-7SDS of cas: 623-00-7)

4-Bromobenzonitrile(cas: 623-00-7) has been used in the synthesis of 4-iodobenzonitrile via photo-induced aromatic Finkelstein iodination reaction.SDS of cas: 623-00-7 It can also be used as an aryl halide test compound in developing greener reaction conditions for Suzuki cross-coupling between aryl halides and phenyl boronic acid.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

《Merging electrolysis and nickel catalysis in redox neutral cross-coupling reactions: Experiment and computation for electrochemically induced C-P and C-Se bonds formation》 was published in CCS Chemistry in 2020. These research results belong to Zhu, Chen; Yue, Huifeng; Nikolaienko, Pavlo; Rueping, Magnus. Name: 4-Bromobenzonitrile The article mentions the following:

The authors have achieved a nickel-catalyzed cross-coupling reaction via concerted paired electrolysis under mild reaction conditions. In this electrochem. transformation, the anodic oxidation of Ni(II) to Ni(III) and cathodic reduction of Ni(I) to Ni(0) occurred simultaneously, resulting in an economical and sustainable cross-coupling protocol. Moreover, mechanistic investigations were performed utilizing experiments and d. functional theory (DFT) calculations for different C-heteroatom bond formations to reveal the catalytic cycle in more detail. In the experiment, the researchers used 4-Bromobenzonitrile(cas: 623-00-7Name: 4-Bromobenzonitrile)

4-Bromobenzonitrile(cas: 623-00-7) is classified as organic nitriles, which are commonly use solvents and are reacted further for various applications such as manufacture of polymers and intermediates for pharmaceuticals and other organic chemicals,Name: 4-Bromobenzonitrile It can also be used as an aryl halide test compound in developing greener reaction conditions for Suzuki cross-coupling between aryl halides and phenyl boronic acid.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

《Nickel-Catalyzed Cyanation of Aryl Halides and Hydrocyanation of Alkynes via C-CN Bond Cleavage and Cyano Transfer》 was written by Chen, Hui; Sun, Shuhao; Liu, Yahu A.; Liao, Xuebin. Reference of 4-Bromobenzonitrile And the article was included in ACS Catalysis in 2020. The article conveys some information:

We report nickel-catalyzed cyanation and hydrocyanation methods to prepare aryl nitriles and vinyl nitriles from aryl halides and alkynes, resp. Using inexpensive and nontoxic 4-cyanopyridine N-oxide as the cyano shuttle, the methods provide an efficient approach to prepare aryl cyanides and vinyl nitriles under mild and operationally simple reaction conditions with a broad range of functional group tolerances. In hydrocyanation of alkynes, the method demonstrated good regioselectivity, producing predominantly E- or Z-alkenyl nitriles in a controlled manner and exclusively Markovnikov vinyl nitriles when internal diaryl alkynes and terminal alkynes were applied as the substrates, resp. The preliminary mechanistic investigation indicated that the C-CN bond cleavage process is promoted by oxidative addition to the nickel(I) complex in the cyanation of aryl halides, and further studies via a series of deuterium exchange experiments indicated that water serves as the hydrogen source for the hydrocyanation of alkynes. In the experiment, the researchers used many compounds, for example, 4-Bromobenzonitrile(cas: 623-00-7Reference of 4-Bromobenzonitrile)

4-Bromobenzonitrile(cas: 623-00-7) has been used in the synthesis of 4-iodobenzonitrile via photo-induced aromatic Finkelstein iodination reaction.Reference of 4-Bromobenzonitrile It can also be used as an aryl halide test compound in developing greener reaction conditions for Suzuki cross-coupling between aryl halides and phenyl boronic acid.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

The author of 《Tuning the porosity and photocatalytic performance of triazine-based graphdiyne polymers through polymorphism》 were Schwarz, Dana; Acharjya, Amitava; Ichangi, Arun; Kochergin, Yaroslav S.; Lyu, Pengbo; Opanasenko, Maksym V.; Tarabek, Jan; Vacek Chocholousova, Jana; Vacek, Jaroslav; Schmidt, Johannes; Cejka, Jiri; Nachtigall, Petr; Thomas, Arne; Bojdys, Michael J.. And the article was published in ChemSusChem in 2019. Application of 623-00-7 The author mentioned the following in the article:

Crystalline and amorphous organic materials are an emergent class of heterogeneous photocatalysts for the generation of hydrogen from water, but a direct correlation between their structures and the resulting properties has not been achieved so far. To make a meaningful comparison between structurally different, yet chem. similar porous polymers, two porous polymorphs of a triazine-based graphdiyne (TzG) framework are synthesized by a simple, one-pot homocoupling polymerization reaction using as catalysts CuI for TzGCu and PdII/CuI for TzGPd/Cu. The polymers form through irreversible coupling reactions and give rise to a crystalline (TzGCu) and an amorphous (TzGPd/Cu) polymorph. Notably, the crystalline and amorphous polymorphs are narrow-gap semiconductors with permanent surface areas of 660 m2 g-1 and 392 m2 g-1, resp. Hence, both polymers are ideal heterogeneous photocatalysts for water splitting with some of the highest hydrogen evolution rates reported to date (up to 972 μmol h-1 g-1 with and 276 μmol h-1 g-1 without Pt cocatalyst). Crystalline order is found to improve delocalization, whereas the amorphous polymorph requires a cocatalyst for efficient charge transfer. This will need to be considered in future rational design of polymer catalysts and organic electronics. After reading the article, we found that the author used 4-Bromobenzonitrile(cas: 623-00-7Application of 623-00-7)

4-Bromobenzonitrile(cas: 623-00-7) has been used in the synthesis of 4-iodobenzonitrile via photo-induced aromatic Finkelstein iodination reaction.Application of 623-00-7 It can also be used as an aryl halide test compound in developing greener reaction conditions for Suzuki cross-coupling between aryl halides and phenyl boronic acid.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

In 2019,Nature Catalysis included an article by Zhu, Chen; Yue, Huifeng; Maity, Bholanath; Atodiresei, Iuliana; Cavallo, Luigi; Rueping, Magnus. Computed Properties of C7H4BrN. The article was titled 《A multicomponent synthesis of stereodefined olefins via nickel catalysis and single electron/triplet energy transfer》. The information in the text is summarized as follows:

Herein, a one-pot difunctionalization of alkynes via a photoredox/nickel dual-catalyzed three-component cross-coupling reaction under mild conditions, providing access to a series of highly important tri-substituted alkenes. Notably, in contrast to traditional methods that are based on the steric hindrance of the substrates to control the reaction selectivity, both E- and Z-isomers of tri-substituted alkenes, which are often energetically close, can be obtained by choosing an appropriate photocatalyst with a suitable triplet state energy. Beyond the immediate practicality of this transformation, this newly developed methodol. might inspire the development of diverse and important one-pot functionalizations of carbon-carbon multiple bonds via photoredox and transition-metal dual-catalyzed multicomponent reactions. In the experimental materials used by the author, we found 4-Bromobenzonitrile(cas: 623-00-7Computed Properties of C7H4BrN)

4-Bromobenzonitrile(cas: 623-00-7) is classified as organic nitriles, which are commonly use solvents and are reacted further for various applications such as manufacture of polymers and intermediates for pharmaceuticals and other organic chemicals,Computed Properties of C7H4BrN It can also be used as an aryl halide test compound in developing greener reaction conditions for Suzuki cross-coupling between aryl halides and phenyl boronic acid.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

In 2019,Organic Letters included an article by Liao, Jennie; Basch, Corey H.; Hoerrner, Megan E.; Talley, Michael R.; Boscoe, Brian P.; Tucker, Joseph W.; Garnsey, Michelle R.; Watson, Mary P.. Quality Control of 4-Bromobenzonitrile. The article was titled 《Deaminative Reductive Cross-Electrophile Couplings of Alkylpyridinium Salts and Aryl Bromides》. The information in the text is summarized as follows:

A nickel-catalyzed reductive cross-coupling of alkylpyridinium salts and aryl bromides has been developed using Mn as the reductant. Both primary and secondary alkylpyridinium salts can be used, and high functional group and heterocycle tolerance is observed, including for protic groups. Mechanistic studies indicate the formation of an alkyl radical, and controlling its fate was key to the success of this reaction. In the experiment, the researchers used 4-Bromobenzonitrile(cas: 623-00-7Quality Control of 4-Bromobenzonitrile)

4-Bromobenzonitrile(cas: 623-00-7) is classified as organic nitriles, which are commonly use solvents and are reacted further for various applications such as manufacture of polymers and intermediates for pharmaceuticals and other organic chemicals,Quality Control of 4-Bromobenzonitrile It can also be used as an aryl halide test compound in developing greener reaction conditions for Suzuki cross-coupling between aryl halides and phenyl boronic acid.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts