Category: 622-75-3

Electric Literature of 622-75-3, A common heterocyclic compound, 622-75-3, name is 2,2′-(1,4-Phenylene)diacetonitrile, molecular formula is C10H8N2, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

Ag(CF3SO3) (0.0231g, 0.090mmol) and p-phda (0.0281g, 0.180mmol) were dissolved in 10mL benzene. After stirring for 30min, the resultant solution were transformed to a Teflon-lined stainless steel vessel (25mL) and heated at 120C for 2h, and then cooled to room temperature naturally. The resulting colorless crystals of 2 were isolated by slow evaporation the solution in air. Yield: 69.80% (based on Ag). Anal. Calc. for C21H16AgF3N4O3S C, 44.30; N, 9.84; H, 2.83; Found: C, 44.03; N, 9.74; H, 2.70%. IR:(KBr, nu/cm-1): 2960(w), 2918(w), 2258(w), 1521(m), 1427(m), 1410(m), 1288(s), 1255(s), 1224(m), 1174(s), 1031(s), 933(m), 785(m), 761(m), 629(s), 519(m).

The synthetic route of 622-75-3 has been constantly updated, and we look forward to future research findings.

Reference:
Article; Han, Jing; Yang, Jian; Yu, Zhong; Wang, Quan-jiu; Inorganica Chimica Acta; vol. 469; (2018); p. 318 – 324;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 622-75-3, name is 2,2′-(1,4-Phenylene)diacetonitrile, This compound has unique chemical properties. The synthetic route is as follows., Formula: C10H8N2

Add p-hydroxybenzaldehyde (0.01 mol, 1.22 g) and epichlorohydrin (0.10 mol, 9.25 g) to a 250 mL single-necked bottle with magnets, heat up to 68 C, and add tetrabutyl dibutyl ether after the raw materials are dissolved. Ammonium bromide (0.001mol, 0.322g). After 8 hours of reaction, terephthalonitrile (0.0045mol, 0.7000g) and 150mL of ethanol were added. After stirring for 10 minutes, solid sodium hydroxide (0.03mol, 1.20g) was added. , Continue the reaction for 4 to 6 hours and stop the reaction.After the temperature of the reaction system dropped to room temperature, suction filtration was performed to collect the solid product, washed with water, and dried to obtain a crude product. The crude product was recrystallized from a mixed solvent of DMF and ethanol (V: V = 3: 1) to obtain a pure yellow product 1.95. g, yield 93%.

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 622-75-3.

Reference:
Patent; Xiangtan University; Zhang Hailiang; Tan Huiping; Yuan Yongjie; Yang Bohao; (15 pag.)CN110407772; (2019); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 622-75-3, name is 2,2′-(1,4-Phenylene)diacetonitrile, This compound has unique chemical properties. The synthetic route is as follows., Recommanded Product: 2,2′-(1,4-Phenylene)diacetonitrile

Add 3,4-bis (2-oxiranylmethoxy) benzaldehyde (0.01mol, 0.25g), terephthalonitrile (0.0045mol, 0.7000g), and 150mL of ethanol to a 250mL single-necked bottle in this order. After stirring for about 10 minutes, solid sodium hydroxide (0.02 mol, 0.80 g) was added, and the reaction was stopped after about 5-6 hours.After the reaction system was cooled to room temperature, suction filtration was performed to collect the solid product, washed with water, and dried to obtain a crude product. The crude product was recrystallized from a mixed solvent of DMF and ethanol (V: V = 3: 1) to obtain 2.65 g of a pure product. The yield was 94%.

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 622-75-3.

Reference:
Patent; Xiangtan University; Zhang Hailiang; Tan Huiping; Yuan Yongjie; Yang Bohao; (15 pag.)CN110407772; (2019); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 622-75-3, name is 2,2′-(1,4-Phenylene)diacetonitrile, This compound has unique chemical properties. The synthetic route is as follows., Formula: C10H8N2

A mixture of 2,2′-(1,4-phenylene)diacetonitrile, 1-bromopyrrolidine- 2,5-dione (2.6 g, 14.73 mmol) benzoic peroxyanhydride (0.36 g, 1.47 mmol) in CCl4 (30 mL) was stirred at 75-80 C for 4 hours. A second reaction mixture of 2,2′-(1,4- phenylene)diacetonitrile (2.0 g, 12.81 mmol) 1-bromopyrrolidine-2,5-dione (2.279 g, 12.81 mmol) benzoic peroxyanhydride (0.310 g, 1.281 mmol) in CCl4 (30 mL) was stirred at 75- 80 C for 4 hours. The mixtures were combined, then concentrated. The residue was purified by flash chromatography (eluted by petroleum ether:ethyl acetate = 20:1 – 1:1) to afford 2-bromo-2-(4-(cyanomethyl)phenyl)acetonitrile (2.6 g, 11.1 mmol).1H NMR (400 MHz, CDCl3) delta ppm 7.32 (d, J = 8.2 Hz, 2H), 7.17 (d, J = 8.1 Hz, 2H), 5.23 (s, 1H), 3.51 (s, 2H).

According to the analysis of related databases, 622-75-3, the application of this compound in the production field has become more and more popular.

Reference:
Patent; GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED; ADAMS, Nicholas David; BENOWITZ, Andrew B.; RUEDA BENEDE, Maria Lourdes; EVANS, Karen Anderson; FOSBENNER, David T.; KING, Bryan Wayne; LI, Mei; MILLER, William Henry; REIF, Alexander Joseph; ROMERIL, Stuart Paul; SCHMIDT, Stanley J.; WIGGALL, Kenneth; (1283 pag.)WO2017/216726; (2017); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Application of 622-75-3, A common heterocyclic compound, 622-75-3, name is 2,2′-(1,4-Phenylene)diacetonitrile, molecular formula is C10H8N2, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

Scheme I, step A: Into a 250 ML single neck flask was placed sodium hydride 60% (5.4 g, 134.5 mmol) in DMF (100 ML) at -15 C. 1,4-Phenyldiacetonitrile (5 g, 32 mmol) was added to the solution slowly and the mixture was stirred for 1/2 hour.The reaction mixture was treated with methyl iodide (8.4 ML, 134.5 mmol).The mixture was warmed up to RT while stirring for 12 hours.The reaction mixture was poured into ice water (600 ML) until product was precipitated out.The precipitate was filtered off and washed with cold water to provide the intermediate title compound, 2-[4-(1-cyano-isopropyl)phenyl]-2-methylpropanenitrile, (6.8 g, 100%) as a white solid.Electron spray M.S. 230 (M*+H2O).

The synthetic route of 622-75-3 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Knobelsdorf, James Allen; Shepherd, Timothy Alan; Tromiczak, Eric George; Zarrinmayeh, Hamideh; Zimmerman, Dennis Michael; US2003/229102; (2003); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Application of 622-75-3, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 622-75-3, name is 2,2′-(1,4-Phenylene)diacetonitrile, This compound has unique chemical properties. The synthetic route is as follows.

1,4-Benzene diacetonitrile solid (0.312 g, 2 mmol) and pyridine-4-carbaldehyde liquid (0.45 mL, 4.4 mmol) were added to a round bottom flask containing dichloromethane (40 mL). When the solid is completely dissolved, the solution is brownish yellow. The mixture was heated and stirred at 50 C in a water bath, and 0.45 mL of tetrabutylammonium hydroxide (TBAH, 40% methanol solution) was added by a syringe, and the solution was changed from brownish yellow to dark green. The reaction was stirred with a water bath at 50 C for 2 h, and TLC showed the reaction was completed. The solvent was evaporated to dryness with a rotary evaporator, and the solid was washed with water, filtered, and filtered, and then filtered, and then filtered and washed with EtOAc. The solid was 0.49 g. The yield was 73.5%.

The chemical industry reduces the impact on the environment during synthesis 2,2′-(1,4-Phenylene)diacetonitrile. I believe this compound will play a more active role in future production and life.

Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 622-75-3, Name is 2,2′-(1,4-Phenylene)diacetonitrile, SMILES is N#CCC1=CC=C(CC#N)C=C1, belongs to nitriles-buliding-blocks compound. In a document, author is Tuzen, Mustafa, introduce the new discover, Category: nitriles-buliding-blocks.

Poly(styrene)-co-2-vinylpyridine copolymer as a novel solid-phase adsorbent for determination of manganese and zinc in foods and vegetables by FAAS

The aim of this study is to extract zinc and manganese from foods and vegetables using an amphiphilic copolymer adsorbent, poly(styrene)-co-2-vinylpyridine which was synthesized via reversible addition fragmentation chain transfer (RAFT) polymerization from styrene and 2-vinyl pyridine in the presence of a trithiocarbonate and 2,2 ‘-azo-bis isobutyro nitrile (AIBN) in toluene solution under argon at 80 degrees C. Fourier Transform Infrared (FTIR) and proton nuclear magnetic resonance (H-1 NMR) spectroscopy were used in the characterization of the obtained copolymer. Under the optimum conditions, several validation variables such as uncertainty measurement, selectivity, robustness, precisions, matrix effects and accuracy were investigated. Taking an adsorption time of 15 min, detection limits of 0.04 mu g L-1 and 0.2 mu g L-1 and 7.9 mu g L-1 and enrichment factors of 145 and 110 were obtained for Mn(II) and Zn(II), respectively. The method was successfully applied to the analysis of Mn(II) and Zn(II) in foods and vegetables.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 622-75-3 is helpful to your research. Category: nitriles-buliding-blocks.

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, such as the rate of change in the concentration of reactants or products with time. 622-75-3, Name is 2,2′-(1,4-Phenylene)diacetonitrile, formurla is C10H8N2. In a document, author is Ogunsona, Emmanuel, introducing its new discovery. Computed Properties of C10H8N2.

Nanocellulose-triggered structural and property changes of acrylonitrile-butadiene rubber films

In this study, the effect of cellulose nanocrystals (CNCs) incorporation on the structure-properties of acrylonitrile-butadiene rubber (NBR films), with particular focus on curing enhancement and reinforcing potential, was investigated. The NBR crosslinking efficiency, observed from nuclear magnetic resonance analysis, increased with successive CNC concentration increases due to better dispersion of ZnO from Zn-cellulose complex formation. Energy dispersive X-ray and transmission electron microscope analysis of the films revealed increasingly well-dispersed ZnO with increasing CNC. The increase in the crosslinking density in conjuncture with the reinforcing capability of CNCs resulted in increases in the tensile strength, stiffness, toughness, tear strength and elongation by 203, 8300, 664, 179, and 14%, respectively for films containing 3 phr CNC compared to the neat NBR. The incorporation of 0.5 phr CNC reduced the water absorption of neat CNC by 250%. Overall, water absorption of the nanocomposite films was considerably lower than that of the neat NBR through CNC consolidation of the rubber particles by reducing free volume in the NBR structure. The nanocomposite films show promise for glove and other dipped product applications where improved tear resistance and overall physical properties improvement are needed without compromising the integrity. (C) 2020 Elsevier B.V. All rights reserved.

If you are hungry for even more, make sure to check my other article about 622-75-3, Computed Properties of C10H8N2.

In an article, author is Jin, Lei, once mentioned the application of 622-75-3, Name is 2,2′-(1,4-Phenylene)diacetonitrile, molecular formula is C10H8N2, molecular weight is 156.18, MDL number is MFCD00001923, category is nitriles-buliding-blocks. Now introduce a scientific discovery about this category, Recommanded Product: 2,2′-(1,4-Phenylene)diacetonitrile.

Highly Proton Conductive Sulfonyl Imide Based Polymer Blended from Poly(arylene ether sulfone) and Parmax-1200 for Fuel Cells

Thermally and chemically stable, sulfonyl imide-based polymer blends have been prepared from sulfonimide poly(arylene ether sulfone) (SI-PAES) and sulfonimide Parmax-1200 (SI-Parmax-1200) using the solvent casting method. Initially, sulfonimide poly(arylene ether sulfone) (SI-PAES) polymers have typically been synthesized via direct polymerization of bis(4-chlorophenyl) sulfonyl imide (SI-DCDPS) and bis(4-fluorophenyl) sulfone (DFDPS) with bisphenol A (BPA). Subsequently, SI-Parmax-1200 has been synthesized via post-modification of the existing Parmax-1200 polymer followed by sulfonation and imidization. The SI-PAES/SI-Parmax-1200 blend membranes show high ion exchange capacity ranging from 1.65 to 1.97 meq/g, water uptake ranging from 22.8 to 65.4% and proton conductivity from 25,9 to 78.5 mS/cm. Markedly, the SI-PAES-40/SI-Parmax-1200 membrane (blended-40) exhibits the highest proton conductivity (78.5 mS/cm), which is almost similar to Nafion 117 (R) (84.73 mS/cm). The thermogravimetric analysis (TGA) and Fenton’s test confirm the excellent thermal and chemical stability of the synthetic polymer blends. Furthermore, the scanning electron microscopy (SEM) study shows a distinct phase separation at the hydrophobic/hydrophilic segments, which facilitate proton conduction throughout the ionic channel of the blend polymers. Therefore, the synthetic polymer blends represent an alternative to Nafion 117 (R) as proton exchangers for fuel cells.

Do you like my blog? If you like, you can also browse other articles about this kind. Thanks for taking the time to read the blog about 622-75-3, Recommanded Product: 2,2′-(1,4-Phenylene)diacetonitrile.

Chemistry can be defined as the study of matter and the changes it undergoes. You¡¯ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology. 622-75-3, Name is 2,2′-(1,4-Phenylene)diacetonitrile, molecular formula is , belongs to nitriles-buliding-blocks compound. In a document, author is Lin, Guo, Application In Synthesis of 2,2′-(1,4-Phenylene)diacetonitrile.

Tungstophosphoric acid-doped sulfonated poly(arylene ether nitriles) composite membranes with improved proton conductivity and excellent long-term stability

A series of composite membranes based on sulfonated poly(arylene ether nitriles) (SPEN) with embedded tungstophosphoric acid (TPA) were prepared. The effect of TPA concentration on morphology, structure, thermal stability, mechanical strength, ion-exchange capacity and proton conductivity of SPEN-TPA composite membranes was studied in detailed. SEM images indicated the TPA were uniformly distributed throughout the SPEN membranes matrix, which is due to the hydrogen bonding networks and the electrostatic interactions in the composites. The existence of hydrogen bonds was also confirmed by FTIR. Benefiting from these, the composite membranes showed higher IEC, mechanical strength, and higher water uptake compared to pristine SPEN. The proton conductivity of the SPEN-TPA composite membranes were dominated by the TPA concentration. The proton conductivity of SPEN-50TPA achieved the highest value of 0.107 S/cm at 80 degrees C, which is 4.4 times as high as that of pristine SPEN. Moreover, it also showed excellent long-term stability, as the TPA did not show any leakage after 120 h at 80 degrees C. Furthermore, activation energy of proton conductivity imply coexistence of Grotthuss and vehicle mechanisms in the composite membranes. These results indicate that SPEN-TPA composite membrane have great potential as proton exchange membrane with high performance.

If you are hungry for even more, make sure to check my other article about 622-75-3, Application In Synthesis of 2,2′-(1,4-Phenylene)diacetonitrile.