Category: 62088-13-5

Adding a certain compound to certain chemical reactions, such as: 62088-13-5, name is Ethyl 3-(3-cyanophenyl)-3-oxopropanoate, belongs to nitriles-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 62088-13-5, Application In Synthesis of Ethyl 3-(3-cyanophenyl)-3-oxopropanoate

Example K9 {2-[3-(3-Cyano-phenyl)-3-oxo-propionylamino]-4-furan-3-yl-phenyl}-carbamic Acid tert.-Butyl Ester Prepared from (2-amino-4-furan-3-yl-phenyl)-carbamic acid tert.-butyl ester (Example G11) and 3-(3-cyano-phenyl)-3-oxo-propionic acid ethyl ester (Pol. J. Chem. 1978, 25) according to the general procedure K. Obtained as an orange solid (460 mg). MS (ISP) 446 [(M+H)+], 463 [(M+NH4)+] and 468 [(M+Na)+]

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Reference:
Patent; Hoffmann-La Roche Inc.; US6509328; (2003); B1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 62088-13-5, name is Ethyl 3-(3-cyanophenyl)-3-oxopropanoate, This compound has unique chemical properties. The synthetic route is as follows., Product Details of 62088-13-5

Part A: Preparation of ethyl 5-(3-cyanophenyl)-1-methyl-1H-pyrazole-4-carboxylate A mixture of ethyl-3-cyanobenzoylacetate (1.0 G, 5 mmol) and N,N-dimethylformamide dimethylacetal (2.74 G, 14 mmol) was heated to 100 C. for 24 h. The reaction mixture was concentrated in vacuo and the residue was re-dissolved in methanol (5 Ml), followed by addition of methyl hydrazine (0.3 Ml, 6 mmol). The reaction mixture was stirred at room temperature for 2 h and then concentrated in vaccuo. The residue was partitioned between ethyl acetate-water (60 Ml, 4:1), washed with water, dried over Na2SO4 and concentrated. The crude was purified using silica gel column chromatography (1 to 15% ethyl acetate-dichloromethane) to yield 0.36 G of required regioisomer; ethyl 5-(3-cyanophenyl)-1-methyl-1H-pyrazole-4-carboxylate and 0.3 G of ethyl 3-(3-cyanophenyl)-1-methyl-1H-pyrazole-4-carboxylate. MS m/z 256.3(M+H)

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 62088-13-5.

Reference:
Patent; Purandare, Ashok Vinayak; Chen, Zhong; US2007/60589; (2007); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts