Adding a certain compound to certain chemical reactions, such as: 5724-56-1, name is 2,3-Dimethylbenzonitrile, belongs to nitriles-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 5724-56-1, Safety of 2,3-Dimethylbenzonitrile
Description 1: 2,3-Bis(bromomethyl)benzonitrile. A mixture of 2,3-dimethylbenzonitrile (available from Fluorochem, 5g, 38.1 mmol), N- bromosuccinimide (13.6g, 76.2mmol) and benzoyl peroxide (460mg, 1.9mmol) in carbon tetrachloride (270ml) was stirred and heated at 800C for 20 hours then cooled and washed with 4x60ml of water. The organic phase was dried (magnesium sulphate), evaporated and purified by flash chromatography eluting with ethyl acetate/iso-hexane (1 :9) to give a yellow solid which was 58% pure by LC/MS. 1H NMR (CDCI3) delta : 4.63 (2H, s), 4.82 (2H, s), 7.43 (1 H, t), 7.64 (2H, m).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2,3-Dimethylbenzonitrile, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; GLAXO GROUP LIMITED; WO2009/80729; (2009); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts