Category: 5653-62-3

V., Bhavadhaarani published the artcileCombined treatment of synthetic textile effluent using mixed azo dye by phyto and phycoremediation, Recommanded Product: 2,3-Dimethoxybenzonitrile, the main research area is azo dye textile effluent phytoremediation bioadsorptive wastewater treatment; Phycoremediation; phytoremediation; textile effluent.

Phytoremediation is one of the biol. approaches for remediating textile dyeing effluents. The objective of this study is the use of Pistia stratiotes, an aquatic macrophyte, which was found to degrade the maximum of 83% of mixed azo dye. A phytoreactor was designed and constructed to scale up the process of phytoremediation by P. stratiotes to treat 40mg/l of synthetic textile effluent. Continuous flow phytoreactor fed with 40mg/l (cycle 1) which showed maximum decolorization of 84%, COD removal was about 61%, BOD which was reduced up to 71.9%, and TDS removal was about 72% resp. Further to remove the residual color and toxic effects of the dyes, Phycoremediation was followed for the mixed azo dyes using the microalgae Chlorella vulgaris which showed a maximum decolorization of 99% in the batch study and 74% in the scale-up study where the treated effluent was at the most minimal discharge. Phytotoxicity tests showed 80% of germination in treated effluent, and the plants in untreated wastewater had inhibited growth that indicates only 30% of germination. Such combined biol. treatment techniques were put forward to be the most eco-friendly technol., which is cost-effective and attain zero discharge of the textile effluent.

International Journal of Phytoremediation published new progress about Azo dyes. 5653-62-3 belongs to class nitriles-buliding-blocks, name is 2,3-Dimethoxybenzonitrile, and the molecular formula is C9H9NO2, Recommanded Product: 2,3-Dimethoxybenzonitrile.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Islam, Sk Manirul published the artcilePolymer-anchored Ru(II) complex as an efficient catalyst for the synthesis of primary amides from nitriles and of secondary amides from alcohols and amines, Formula: C9H9NO2, the main research area is nitrile polymer anchored ruthenium complex hydration catalyst; primary amide preparation green chem; alc amine polymer anchored ruthenium complex oxidative coupling catalyst; secondary amide preparation green chem; polymer anchored ruthenium complex preparation hydration oxidative amidation catalyst.

A polymer-anchored ruthenium(II) catalyst was synthesized and characterized. Its catalytic activity was evaluated for the preparation of primary amides from aqueous hydration of nitriles in neutral condition. A range of nitriles were successfully converted to their corresponding amides in good to excellent yields. The catalyst was also effective in the preparation of secondary amides from the coupling of alcs. and amines. The catalyst can be facilely recovered and reused six times without a significant decrease in its activity.

Applied Organometallic Chemistry published new progress about Amidation. 5653-62-3 belongs to class nitriles-buliding-blocks, name is 2,3-Dimethoxybenzonitrile, and the molecular formula is C9H9NO2, Formula: C9H9NO2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nelson, Derek W. published the artcileStructure-Activity Relationship Studies on a Series of Novel, Substituted 1-Benzyl-5-phenyltetrazole P2X7 Antagonists, Name: 2,3-Dimethoxybenzonitrile, the main research area is enzylphenyltetrazole derivative SAR preparation P2X7 receptor antagonist.

1-Benzyl-5-aryltetrazoles were discovered to be novel antagonists for the P2X7 receptor. Structure-activity relationship (SAR) studies were conducted around both the benzyl and Ph moieties. In addition, the importance of the regiochem. substitution on the tetrazole was examined Compounds were evaluated for activity to inhibit calcium flux in both human and rat recombinant P2X7 cell lines using fluorometric imaging plate reader technol. Analogs were also assayed for their ability to inhibit IL-1β release and to inhibit P2X7-mediated pore formation in human THP-1 cells. Compound 15d was advanced to efficacy studies in a model of neuropathic pain where significant reversal of mech. allodynia was observed at doses that did not affect motor coordination.

Journal of Medicinal Chemistry published new progress about Allodynia. 5653-62-3 belongs to class nitriles-buliding-blocks, name is 2,3-Dimethoxybenzonitrile, and the molecular formula is C9H9NO2, Name: 2,3-Dimethoxybenzonitrile.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Campaigne, E. published the artcileCyclization of ylidenemalononitriles. VIII. Synthesis of coumarins from o-methoxybenzylidenemalonitriles, Formula: C9H9NO2, the main research area is coumarin; malononitrile benzylidene cyclization; cyclization benzylidenemalononitrile.

The coumarins I (R = H, Cl; R1 = H, 6-,7-,8-MeO) were prepared by direct cyclization of α-cyano-o-methoxycinnamates (II) in H2SO4. Alkoxy groups other than the o-methoxy group involved in lactone formation are not hydrolyzed during the reaction. The 3-cyano group on the resulting coumarin is not hydrated in concentrated H2SO4, but can be converted to the carbamido group in 90% sulfuric acid. In certain cases these conditions do cleave methoxy substituents on the coumarins. The indenones III can be obtained by cyclizing the II with BF3.Et2O.

Journal of Heterocyclic Chemistry published new progress about Cyclization. 5653-62-3 belongs to class nitriles-buliding-blocks, name is 2,3-Dimethoxybenzonitrile, and the molecular formula is C9H9NO2, Formula: C9H9NO2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Campaigne, E. published the artcileCyclization of ylidenemalononitriles. VIII. Synthesis of coumarins from o-methoxybenzylidenemalonitriles, Formula: C9H9NO2, the main research area is coumarin; malononitrile benzylidene cyclization; cyclization benzylidenemalononitrile.

The coumarins I (R = H, Cl; R1 = H, 6-,7-,8-MeO) were prepared by direct cyclization of α-cyano-o-methoxycinnamates (II) in H2SO4. Alkoxy groups other than the o-methoxy group involved in lactone formation are not hydrolyzed during the reaction. The 3-cyano group on the resulting coumarin is not hydrated in concentrated H2SO4, but can be converted to the carbamido group in 90% sulfuric acid. In certain cases these conditions do cleave methoxy substituents on the coumarins. The indenones III can be obtained by cyclizing the II with BF3.Et2O.

Journal of Heterocyclic Chemistry published new progress about Cyclization. 5653-62-3 belongs to class nitriles-buliding-blocks, name is 2,3-Dimethoxybenzonitrile, and the molecular formula is C9H9NO2, Formula: C9H9NO2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Rajagopal, Krishnamurthy published the artcileKerr effect of some new organic Kerr solutions, Computed Properties of 5653-62-3, the main research area is electrooptical Kerr effect organic solution.

The electro optic Kerr constant of many new organic solutions comprising of the substituted aromatic carbonyl and nitrile compounds as solutes in nitrobenzene, for various molar concentrations of the solutes has been measured. We found several solutions having Kerr constants greater than that of nitrobenzene. The interactions between the components in these solutions have been established to be dipole-dipole in nature for the first time by conducting experiments and measuring the dipole moments for solutions of various molar concentrations The variations of the dipole moment with concentration in many solutions have been found to follow the same trend of variations of Kerr constant with molar concentration

Journal of the Physical Society of Japan published new progress about Dipole moment. 5653-62-3 belongs to class nitriles-buliding-blocks, name is 2,3-Dimethoxybenzonitrile, and the molecular formula is C9H9NO2, Computed Properties of 5653-62-3.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Jie, Zhou published the artcileDiethyl Chlorophosphite: A Versatile Reagent, Recommanded Product: 2,3-Dimethoxybenzonitrile, the main research area is diethyl chlorophosphite reaction oxygenated functional group.

Di-Et chlorophosphite (DECP) was previously described as a reducing agent for nitro compounds to amines (B. Fischer and L. Sheihet, J. Organic Chem. 1998, 63, 393). Here, the utility of this reagent was extended to chem. conversions of other oxygenated functional groups. In this paper we report on the scope of the reaction of DECP with N-oxides, epoxides, sulfones, sulfoxides, hydroxylamines, ketoximes, and aldoximes. The chemoselectivity of DECP is described, and conditions for a stepwise multiple conversion of functional groups on the same mol. with this reagent are provided.

Journal of Organic Chemistry published new progress about diethyl chlorophosphite reaction oxygenated functional group. 5653-62-3 belongs to class nitriles-buliding-blocks, name is 2,3-Dimethoxybenzonitrile, and the molecular formula is C9H9NO2, Recommanded Product: 2,3-Dimethoxybenzonitrile.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Al-Rubaie, Ali Z. published the artcilePalladium-catalyzed formation of 3,5-diaryl-1,2,4-selenadiazoles from arylselenocarboxamide, COA of Formula: C9H9NO2, the main research area is diarylselenadiazole preparation; arylselenocarboxamide preparation cyclization; selenadiazole diaryl preparation.

A number of new and known arylselenocarboxamides RC(:Se)NH2 [R = Ph, 4-BrC6H4, 2-MeOC6H4, 4-MeOC6H4, 4-MeSC6H4, 4-EtOC6H4, 2,3-(MeO)2C6H3, 3,4-(MeO)2C6H3, 3,5-(MeO)2C6H3, 4-PhC6H4, 6-MeOC10H6, 4-MeOC10H6] have been prepared in high yields by the reaction of RCN with NaHSe. Treatment of RC(:Se)NH2 (4 mmol) with aqueous Na2PdCl4 (1 mmol) in acetone at room temperature resulted in the formation of 3,5-diaryl-1,2,4-selenadiazoles (L) as unexpected products together with palladium(II) complexes [PdCl2L]2.2H2O. Treatment of RC(:Se)NH2 (4 mmol) with catalytic amounts of Na2PdCl4 (10-3 mmol) gave only 3,5-diaryl-1,2,4-selenadiazoles in good yields. 3,5-Diaryl-1,2,4-selenodiazoles were also prepared by oxidation of arylselenocarboxamides with iodine for comparison.

Journal of Organometallic Chemistry published new progress about diarylselenadiazole preparation; arylselenocarboxamide preparation cyclization; selenadiazole diaryl preparation. 5653-62-3 belongs to class nitriles-buliding-blocks, name is 2,3-Dimethoxybenzonitrile, and the molecular formula is C9H9NO2, COA of Formula: C9H9NO2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

V., Bhavadhaarani published the artcileCombined treatment of synthetic textile effluent using mixed azo dye by phyto and phycoremediation, Recommanded Product: 2,3-Dimethoxybenzonitrile, the main research area is azo dye textile effluent phytoremediation bioadsorptive wastewater treatment; Phycoremediation; phytoremediation; textile effluent.

Phytoremediation is one of the biol. approaches for remediating textile dyeing effluents. The objective of this study is the use of Pistia stratiotes, an aquatic macrophyte, which was found to degrade the maximum of 83% of mixed azo dye. A phytoreactor was designed and constructed to scale up the process of phytoremediation by P. stratiotes to treat 40mg/l of synthetic textile effluent. Continuous flow phytoreactor fed with 40mg/l (cycle 1) which showed maximum decolorization of 84%, COD removal was about 61%, BOD which was reduced up to 71.9%, and TDS removal was about 72% resp. Further to remove the residual color and toxic effects of the dyes, Phycoremediation was followed for the mixed azo dyes using the microalgae Chlorella vulgaris which showed a maximum decolorization of 99% in the batch study and 74% in the scale-up study where the treated effluent was at the most minimal discharge. Phytotoxicity tests showed 80% of germination in treated effluent, and the plants in untreated wastewater had inhibited growth that indicates only 30% of germination. Such combined biol. treatment techniques were put forward to be the most eco-friendly technol., which is cost-effective and attain zero discharge of the textile effluent.

International Journal of Phytoremediation published new progress about Azo dyes. 5653-62-3 belongs to class nitriles-buliding-blocks, name is 2,3-Dimethoxybenzonitrile, and the molecular formula is C9H9NO2, Recommanded Product: 2,3-Dimethoxybenzonitrile.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Kanaoka, Yuichi published the artcilePolyphosphate ester as a synthetic agent. XII. Convenient synthesis of nitriles by the dehydration of amides with PPE, Application of 2,3-Dimethoxybenzonitrile, the main research area is polyphosphate ester synthesis benzonitrile; benzonitrile polyphosphate ester synthesis; naphthonitrile polyphosphate ester synthesis; furonitrile polyphosphate ester synthesis; nicotinonitrile polyphosphate ester synthesis; cyano cyclohexane polyphosphate ester synthesis; cyclopentane cyano polyphosphate ester synthesis; nitrile benzo polyphosphate ester synthesis.

Nitriles were prepared in improved yields by the dehydration of amides with PPE, prepared from P2O5 and Et2O. Thus, a solution of BzNH2 and PPE in CHCl3 was refluxed 2 hr to give 87% PhCN. m-Nitrobenzonitrile, p-nitrobenzonitrile, o-chlorobenzonitrile, m-hydroxybenzonitrile, p-hydroxybenzonitrile, m-methoxybenzonitrile, p-methoxybenzonitrile, 2,3-dimethoxybenzonitrile, β-naphthonitrile, cyclopentanecarbonitrile, cyclohexanecarbonitrile, phenylacetonitrile, 2-furonitrile, nicotinonitrile, and isonicoinonitrile, were similarly prepared, but 2-furancarboxamide resisted dehydration. The primary amides were prepared by ammonolysis of the corresponding acid chlorides.

Chemical & Pharmaceutical Bulletin published new progress about Nitriles. 5653-62-3 belongs to class nitriles-buliding-blocks, name is 2,3-Dimethoxybenzonitrile, and the molecular formula is C9H9NO2, Application of 2,3-Dimethoxybenzonitrile.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts