54202-05-0, name is Methyl 4-cyanobicyclo[2.2.2]octane-1-carboxylate, belongs to nitriles-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. HPLC of Formula: C11H15NO2
Methyl 4-cyanobicyclo[2.2.2]octane-l-carboxylate (0.83 g, 4.3 mmol) was taken up in methanol (86 mL), H2O (35 mL) and 1 N HCl (8.6 mL) along with PtO2 H2O (430 mg). The resulting reaction was stirred at room temperature under 35 psi of H2 for 5 h. TLC indicated that the reaction was complete (elution: petroleum ethcr/EtOAc=3:l , I2 visualization). The reaction mixture was concentrated under reduced pressure. Saturated
The synthetic route of 54202-05-0 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; SIRTRIS PHARMACEUTICALS, INC.; WO2008/100423; (2008); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts