Category: 38791-62-7

Simple exploration of C14H8N2O

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 4-Phenoxyphthalonitrile, other downstream synthetic routes, hurry up and to see.

Synthetic Route of 38791-62-7, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 38791-62-7, name is 4-Phenoxyphthalonitrile belongs to nitriles-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.

General procedure: 1,2-Diisocyano-4-phenoxy benzene (8) (0.300 g, 1.36 ×10-3 mol) and phenol (0.356 g, 0.0375 mol) in THF was refluxed. The resultant product (9), 1,2-diisocyano-3,4-diphenoxy benzene,(0.300 g, 1.36 × 10-3 mol) was refluxed in 1-pentanol (14 mL)and 1 mol 1,8-diazabicyclo[5.4.0]-undec-7-ene (0.21 g, 1.36× 10-3 mol) for 16 h. Methanol (20 mL) was there after added and the precipitate (2a) filtered off, Soxhlet extracted with methanol and acetone and dried at 60 C. Yield = 0.294 g and yield (%) 43, Rf = 0.23 (ethyl acetate:hexane, 3:8). (KBr, numax,cm-1): 3620 (N-H), 2848 (C-H) aromatic, 1685 (C=C), 1163(C-H), 743 (C-H). UV-visible lambdamax (nm): 337, 606, 640, 661,702. 1H NMR (300 MHz, CDCl3) delta 2.01 (s, 2H, NH), 3.66 (m,4H, CH), 6.99 (m, 4H, ArH), 7.23 (m, 4H, ArH), 7.50 (m, 4H,ArH) 8.04 (m, 4H, ArH), 8.99 (m, 4H, ArH), 9.23 (m, 4H,ArH), 13C NMR (300 MHz, CDCl3) delta 71.01, 76.57, 76.99,77.41, 117.45, 119.69, 119.92, 126.95, 127.48, 127.63, 128.53,128.85, 128.94, 134.43, 135.20. Anal. calcd. C, 76.21; H, 4.19;N, 9.03. Found: C, 76.21; H, 4.18; N, 9.11.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 4-Phenoxyphthalonitrile, other downstream synthetic routes, hurry up and to see.

Reference:
Article; Isabirye, David A.; Seheri, Naledi H.; Aiyelabola, Temitayo O.; Asian Journal of Chemistry; vol. 29; 3; (2017); p. 489 – 495;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

New learning discoveries about 4-Phenoxyphthalonitrile

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 4-Phenoxyphthalonitrile, other downstream synthetic routes, hurry up and to see.

Synthetic Route of 38791-62-7, The chemical industry reduces the impact on the environment during synthesis 38791-62-7, name is 4-Phenoxyphthalonitrile, I believe this compound will play a more active role in future production and life.

11.3 g of compound 1 was dissolved in 30 ml of methanol, added to 25 ml of 50% sodium hydroxide solution, heated to reflux for 48 h. After completion of the reaction, the pH was adjusted to about 3 with concentrated hydrochloric acid, precipitated by precipitation, filtered and dried to give 10.5 g of compound 2.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 4-Phenoxyphthalonitrile, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; BEIJING BETA PHARMA, INC.; (43 pag.)TWI582078; (2017); B;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts