Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 3100-67-2, name is 1-Amino-2-naphthonitrile, This compound has unique chemical properties. The synthetic route is as follows., name: 1-Amino-2-naphthonitrile
A 2 L reactor was charged with 45.0 g (232 mmol) of intermediate 3-a, 450 mL of tetrahydrofuran was added thereto and stirred. after cooling to 0 C, 3M-phenylmagnesium bromide (88.2 mL, 487 mmol) was added dropwise, and refluxed for 3 hours. after cooling to 0 C, 44.3 g (732 mmol) of ethyl chloroformate was dissolved in 200 mL of tetrahydrofuran, and the mixture was refluxed for 2 hours. after cooling to 0 C, a saturated aqueous ammonium chloride solution was added, and the organic layer was extracted with ethyl acetate and water. The organic layer was concentrated under reduced pressure and then separated by column chromatography to obtain 46.0 g (yield: 80.0%) of a compound represented by [Intermediate 3-b].
According to the analysis of related databases, 3100-67-2, the application of this compound in the production field has become more and more popular.
Reference:
Patent; SFC Co.,Ltd; Sin, Bong Gi; Park, Ji Hee; Park, Boo Bae; Park, Gyung Hwa; (46 pag.)KR2016/36162; (2016); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts