Extended knowledge of C11H8N2

According to the analysis of related databases, 3100-67-2, the application of this compound in the production field has become more and more popular.

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 3100-67-2, name is 1-Amino-2-naphthonitrile, This compound has unique chemical properties. The synthetic route is as follows., name: 1-Amino-2-naphthonitrile

A 2 L reactor was charged with 45.0 g (232 mmol) of intermediate 3-a, 450 mL of tetrahydrofuran was added thereto and stirred. after cooling to 0 C, 3M-phenylmagnesium bromide (88.2 mL, 487 mmol) was added dropwise, and refluxed for 3 hours. after cooling to 0 C, 44.3 g (732 mmol) of ethyl chloroformate was dissolved in 200 mL of tetrahydrofuran, and the mixture was refluxed for 2 hours. after cooling to 0 C, a saturated aqueous ammonium chloride solution was added, and the organic layer was extracted with ethyl acetate and water. The organic layer was concentrated under reduced pressure and then separated by column chromatography to obtain 46.0 g (yield: 80.0%) of a compound represented by [Intermediate 3-b].

According to the analysis of related databases, 3100-67-2, the application of this compound in the production field has become more and more popular.

Reference:
Patent; SFC Co.,Ltd; Sin, Bong Gi; Park, Ji Hee; Park, Boo Bae; Park, Gyung Hwa; (46 pag.)KR2016/36162; (2016); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Share a compound : C11H8N2

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1-Amino-2-naphthonitrile, other downstream synthetic routes, hurry up and to see.

Reference of 3100-67-2, The chemical industry reduces the impact on the environment during synthesis 3100-67-2, name is 1-Amino-2-naphthonitrile, I believe this compound will play a more active role in future production and life.

The mixture was stirred into 200 mL of tetrahydrofuran and <9-a>, obtained from scheme 21, 25.0 g (149 mmol), phenyl magnesium bromide (3.0 M in Et2O) 87.4 mL (297 mmol) was added dropwise at 0 C and refluxed for about one hour. Ethyl chloroformate 19.4 g (179 mmol) was added dropwise and it was refluxed for about 1 hour. Then aqueous solution of ammonium chloride was added and then washed with water and heptane to give <9-b> 32.4 g (80% yield).

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1-Amino-2-naphthonitrile, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; SFC Co. Ltd.,; Yoo, Se Jin; Lee, Se Jin; (64 pag.)KR101554545; (2015); B1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Share a compound : 1-Amino-2-naphthonitrile

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1-Amino-2-naphthonitrile, other downstream synthetic routes, hurry up and to see.

Related Products of 3100-67-2, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 3100-67-2, name is 1-Amino-2-naphthonitrile belongs to nitriles-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.

The [Reaction Scheme 1-1 [Intermediate a-1] 50.0 g (297 mmol), 500 mL of dimethylformamide was stirred obtained from. Then N-bromo-succinimide 55.56 g (312 mmol) was added slowly to the reactor. After raising to room temperature and stirred for 4 hours. When the reaction is completed, distilled water was added dropwise thereto at room temperature saenggimyeon brown crystals Crystals were filtered and separated by column chromatography with [intermediate 1-b] compound 68 g. (Yield: 92.6%).

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1-Amino-2-naphthonitrile, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; SFC CO., LTD.; PARK, PU BAE; PARK, JI HEE; SHIN, PONG KI; YOO, JUNG HO; YANG, BYUNG SOON; LEE, SE JIN; (61 pag.)KR2015/111106; (2015); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

The origin of a common compound about 1-Amino-2-naphthonitrile

The synthetic route of 3100-67-2 has been constantly updated, and we look forward to future research findings.

Synthetic Route of 3100-67-2, A common heterocyclic compound, 3100-67-2, name is 1-Amino-2-naphthonitrile, molecular formula is C11H8N2, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

The dried 1 L reactor was charged with nitrogen and then 50.0 g (297 mmol) of intermediate 13-a,500 mL of dimethylformamide is stirred.55.56 g (312 mmol) of N-bromosuccinimide are slowly added to the reactor.Stir at room temperature for 4 hours.When the reaction was completed, distilled water was added dropwise at room temperature to precipitate brown crystals. The crystals were separated by filtration and separated by column chromatography to obtain 68 g of intermediate 13-b.(Yield: 93%)

The synthetic route of 3100-67-2 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; SFC Ltd.; Choi Yeong-tae; Lee Se-jin; Park Seok-bae; Ryu Tae-jeong; Yang Byeong-seon; Lee Da-jeong; (92 pag.)KR2018/10087; (2018); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Sources of common compounds: 3100-67-2

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 3100-67-2.

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 3100-67-2, name is 1-Amino-2-naphthonitrile, This compound has unique chemical properties. The synthetic route is as follows., Product Details of 3100-67-2

After adding nitrogen to the dry reactor 1 L 6-a 50.0 g (297 mmol), 500 mL of dimethylformamide then put the N-bromo-succinimide 55.56 g (312 mmol) slowly to the reactor. And stirred at room temperature for 4 hours. After the reaction was terminated by dropwise addition of distilled water atroom temperature, filtered, the brown crystals were separated by column chromatography to give the 6-b 68 g. (Yield 93%)

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 3100-67-2.

Reference:
Patent; SFC Co.,Ltd; Yang, Byung Son; Lee, Say Jin; Lee, Bong Hyang; Oh, Hyun Ju; Yu, Jong Ho; Hwang, Mun Chan; (67 pag.)KR2015/130797; (2015); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

The origin of a common compound about 1-Amino-2-naphthonitrile

The synthetic route of 3100-67-2 has been constantly updated, and we look forward to future research findings.

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 3100-67-2, name is 1-Amino-2-naphthonitrile, A new synthetic method of this compound is introduced below., Quality Control of 1-Amino-2-naphthonitrile

A solution of 1-amino-2-naphthonitrile (1.00 g, 5.95 mmol) in anhydrous ether (20 mL) was dropwise added to a solution of 1M 3-methoxyphenylmagnesium bromide-tetrahydrofuran solution (17.8 mL, 17.8 mmol) for 10 minutes. The mixture was heated under reflux for one hour. The reaction mixture was poured into 2N hydrochloric acid (30 mL). After addition of methanol (5 mL), the mixture was stirred for 4 hours at room temperature. The mixture was neutralized by addition of potassium carbonate, and the neutralized ether was subjected to extraction with ether. The ether portion was washed with saturated brine and dried over anhydrous sodium sulfate. The dried mixture was placed under reduced pressure to distill the solvent off. The residue was purified by silica gel column chromatography (chloroform/hexane=4/1), to give the titled compound (1.54 g, yield 93%). 1H NMR (CDCl3, 400 MHz) delta: 3.85 (3H, s), 6.98 (1H, d, J=9Hz), 7.06 (1H, dd, J=2, 8Hz), 7.1-7.2 (2H, m), 7.37 (1H, t, J=8Hz), 7.4-7.6 (4H, m), 7.5-7.6 (1H, m), 7.74 (1H, d, J=8Hz), 7.97 (1H, d, J=8Hz).

The synthetic route of 3100-67-2 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Nippon Chemiphar Co., Ltd.; EP2058304; (2009); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Extended knowledge of 3100-67-2

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 3100-67-2, name is 1-Amino-2-naphthonitrile, A new synthetic method of this compound is introduced below., Safety of 1-Amino-2-naphthonitrile

A solution of [Intermediate 7-a] (18.5 g, 0.11 mol) in dimethyl formamide (200 mL) was stirred at 0 C. Drops of a solution of N-bromosuccinimide (20.1 g, 0.11 mol) in dimethyl formamide (100 mL) were slowly added over 1 hr. The reaction mixture was warmed to room temperature and stirred for 12 hrs. Following filtration with an excess of distilled water, the filtrate was washed with methanol and recrystallized in toluene and methanol to afford [Intermediate 7-b] (18.7 g): yield 69%.

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.

Reference:
Patent; SFC CO., LTD.; LEE, Chang-Hee; SEO, Hyun-JONG; YOON, Seo-Yeon; SHIM, So Young; KIM, Si-In; (214 pag.)US2018/233669; (2018); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts