Category: 3032-92-6

Inorganic compounds containing the −C≡N group are not called nitriles, but cyanides instead.3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Though both nitriles and cyanides can be derived from cyanide salts, most nitriles are not nearly as toxic. Synthetic Route of 3032-92-6.

Lin, Hui-Shu;Pan, Yong-Zhou;Tian, Yu-Hong;Pan, Ying-Ming;Wang, Xu research published 《 Palladium-Catalyzed Tandem Cyclization of 2-(2 Ethynylphenyl)acetonitriles and Isocyanides: Access to Indeno[2,1-b]pyrroles》, the research content is summarized as follows. A palladium-catalyzed tandem cyclization of 2-(2-ethynylphenyl)acetonitriles I (R¹ = Ph, naphthalen-2-yl, thiophen-3-yl, etc.) with isocyanides CNR² (R² = tert-Bu, cyclohexyl, adamantan-1-yl, etc.) has been developed. Various indeno[2,1-b]pyrroles II were prepared in 55%-82% yields under air atm. at 100°C. The key to the success of this protocol is construction of new C-C and C-N bonds via the orderly insertion of isocyanides.

Synthetic Route of 3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Industrially, the main methods for producing nitriles are ammoxidation and hydrocyanation. 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Both routes are green in the sense that they do not generate stoichiometric amounts of salts. Computed Properties of 3032-92-6.

Liu, Siqi;Li, Jianying;Hu, Wenli;Huang, Bin;Cai, Mingzhong research published 《 Recyclable gold(I)-catalyzed hydrohydrazidation of terminal alkynes towards keto-N-acylhydrazones》, the research content is summarized as follows. A facile and highly efficient heterogeneous gold(I)-catalyzed hydrohydrazidation of terminal alkynes with diverse hydrazides was developed in chlorobenzene at 60° by using an MCM-41-immobilized diphenylphosphine gold(I) complex [Ph₂P-MCM-41-AuNTf₂] as the catalyst, providing a novel and practical method for the synthesis of a wide variety of substituted keto-N-acylhydrazones in good to excellent yields. This heterogenized gold(I) catalyst was also easy to recover via filtration of the reaction mixture and was recyclable up to eight times without any apparent loss of catalytic efficiency.

3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., Computed Properties of 3032-92-6

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitriles used to be known as cyanides; the smallest organic nitrile is ethanenitrile, CH3CN, (old name: methyl cyanide or acetonitrile – and sometimes now called ethanonitrile). 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Nitriles are found in many useful compounds, including methyl cyanoacrylate, used in super glue, and nitrile rubber, a nitrile-containing polymer used in latex-free laboratory and medical gloves. Name: 4-Ethynylbenzonitrile.

Liu, Yanyao;Ni, Dongshun;Stevenson, Bernard G.;Tripathy, Vikrant;Braley, Sarah E.;Raghavachari, Krishnan;Swierk, John R.;Brown, M. Kevin research published 《 Photosensitized [2+2]-Cycloadditions of Alkenylboronates and Alkenes》, the research content is summarized as follows. A new strategy for the synthesis of highly versatile cyclobutylboronates via the photosensitized [2+2]-cycloaddition of alkenylboronates and alkenes is presented. The process is mechanistically different from other processes in that energy transfer occurs with the alkenylboronate as opposed to the other alkene. This strategy allows for the synthesis of an array of diverse cyclobutylboronates. The conversion of these adducts to other compounds as well as their utility in the synthesis of melicodenine C is demonstrated.

Name: 4-Ethynylbenzonitrile, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitrile is any organic compound with a −C≡N functional group. 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile.The prefix cyano- is used interchangeably with the term nitrile in literature. Name: 4-Ethynylbenzonitrile.

Liu, Yu-Wen;Li, Ling-Jun;Xu, Hui;Dai, Hui-Xiong research published 《 Palladium-Catalyzed Alkynylation of Enones with Alkynylsilanes via C-C Bond Activation》, the research content is summarized as follows. The synthesis of 1,3-enynes via palladium-catalyzed cross coupling between enone derivatives and alkynylsilanes was reported. The employment of appropriate pyridine-oxazoline ligand is the key to the C-C cleavage and the high E/Z stereoselectivity. This protocol features broad substrate scope and wide functional-group tolerance, affording the desired products in moderate-to-good yields. Late-stage diversification of natural product β-ionone further demonstrated the synthetic utility of this protocol.

Name: 4-Ethynylbenzonitrile, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Inorganic compounds containing the −C≡N group are not called nitriles, but cyanides instead.3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Though both nitriles and cyanides can be derived from cyanide salts, most nitriles are not nearly as toxic. Recommanded Product: 4-Ethynylbenzonitrile.

Lokolkar, Manjunath S.;Mane, Pravin A.;Dey, Sandip;Bhanage, Bhalchandra M. research published 《 Synthesis of 2-Substituted Indoles by Pd-Catalyzed Reductive Cyclization of 1-Halo-2-nitrobenzene with Alkynes》, the research content is summarized as follows. An effective process for synthesizing 2-substituted indoles in a one-pot tandem reaction of 1-halo-2-nitrobenzene and terminal alkynes through addition/reductive cyclization is presented. This protocol involves a Sonogashira-type coupling reaction followed by reductive cyclization employing dppf (1,1′-bis(diphenylphosphino)ferrocene) ligated Pd dithiolate complex as a catalyst and Zn as an inexpensive reductant. This efficient and tandem process tolerates broad functional groups with moderate to good yields. The gram-scale synthesis of 2-substituted indole has also been demonstrated. This protocol provides an alternative route for the synthesis of 2-substituted indoles.

Recommanded Product: 4-Ethynylbenzonitrile, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitriles used to be known as cyanides; the smallest organic nitrile is ethanenitrile, CH3CN, (old name: methyl cyanide or acetonitrile – and sometimes now called ethanonitrile). 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Nitriles are found in many useful compounds, including methyl cyanoacrylate, used in super glue, and nitrile rubber, a nitrile-containing polymer used in latex-free laboratory and medical gloves. Safety of 4-Ethynylbenzonitrile.

Kumaki, Wataru;Kinoshita, Hidenori;Miura, Katsukiyo research published 《 Regio- and stereoselective synthesis of bromoalkenes by homolytic hydrobromination of alkynes with hydrogen bromide》, the research content is summarized as follows. Homolytic hydrobromination of terminal and internal alkynes RCCR¹ (R = n-pentyl, 4-chlorophenyl, naphthalen-1-yl, pyridin-2-yl, etc.; R¹ = H, n-pentyl, Ph, Bu, 4-methylphenyl) with a com. available solution of hydrogen bromide in acetic acid has been investigated for regio- and stereoselective synthesis of bromoalkenes (E)/(Z)-RCH=C(Br)R¹. Under an aerobic atm. at room temperature, the reaction of ethynylarenes with a small excess of HBr efficiently gave (2-bromoethenyl)arenes with good to high E-selectivity. (Alk-1-ynyl)arenes, or internal alkynes bearing both Ph and alkyl groups at the sp-carbons also underwent the air-initiated hydrobromination to exhibit high Z-selectivity under kinetic conditions using a half equivalent of HBr.

Safety of 4-Ethynylbenzonitrile, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Industrially, the main methods for producing nitriles are ammoxidation and hydrocyanation. 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Both routes are green in the sense that they do not generate stoichiometric amounts of salts. Application of C9H5N.

Kumar, Gautam;Bhattacharya, Debkanta;Chatterjee, Indranil research published 《 Lewis Acid-Assisted Transition Metal-Free Aminocyanation of Alkynes with Arylamines and N-Cyanosuccinimide》, the research content is summarized as follows. A transition-metal-free aminocyanation of aryl alkynes has been achieved using indium tribromide, InBr₃ or B(C₆F₅)₃ as a Lewis acid. This aminocyanation protocol features with non-toxic cyanide source, a good substrate scope and potentially valuable aminocyanation products. Mechanistic studies reveal the complex formation between Lewis acid and alkyne to produce in situ alkyne nitrile as a key intermediate. Further hydroamination of alkyne nitrile with arylamines affords the E-selective (E:Z = 70:30 to 90:10) β-aminoacrylonitrile derivatives

Application of C9H5N, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Industrially, the main methods for producing nitriles are ammoxidation and hydrocyanation. 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Both routes are green in the sense that they do not generate stoichiometric amounts of salts. Name: 4-Ethynylbenzonitrile.

Kumar, Manoj;Verma, Shalini;Mishra, Vivek;Reiser, Oliver;Verma, Akhilesh K. research published 《 Visible-light-accelerated copper-catalyzed [3 + 2] cycloaddition of N-tosylcyclopropylamines with alkynes/alkenes》, the research content is summarized as follows. Copper-catalyzed [3 + 2] cycloadditions of N-tosylcyclopropylamine with alkynes and alkenes had been accomplished under visible light irradiation The developed approach was compatible with a range of functionalities and allows the synthesis of diversified aminated cyclopentene I [R = Ph, 4-MeOC₆H₄, 6-methoxy-2-naphthyl, etc.] and cyclopentane derivatives II [R¹ = Ph, 4-MeC₆H₄, Bz, etc.] being relevant for drug synthesis. The protocol was operationally simple and economically affordable as it does not require any ligand, base or additives. As the key step, the one-electron oxidation of the N-tosyl moiety by visible light-induced homolysis of a transient Cu(II)-tosylamide complex was proposed, providing a facile entry for N-centered radicals.

3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., Name: 4-Ethynylbenzonitrile

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitriles are found in many useful compounds. Nitrile rubber is also widely used as automotive and other seals since it is resistant to fuels and oils. Organic compounds containing multiple nitrile groups are known as cyanocarbons. 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Nitriles are found in many useful compounds. One of the most common occurrences of nitriles is in Nitrile rubber. Related Products of 3032-92-6.

Lahtigui, Ouidad;Forster, Dan;Duchemin, Coralie;Cramer, Nicolai research published 《 Enantioselective Access to 3-Azabicyclo[3.1.0]hexanes by Cp^xRh^III Catalyzed C-H Activation and Cp*Ir^III Transfer Hydrogenation》, the research content is summarized as follows. A flexible two-step protocol for efficient and selective access such as 3-azabicyclo[3.1.0]hexanes I [R¹ = cyclopropyl, Ph, 3-thienyl, etc.; R² = Bn, PNB] was disclosed. A tailored Cp^xRhIII catalyst promoted alkenyl C-H functionalization of N-enoxysuccinimides engaging in rare cis-cyclopropanation of acrolein to access disubstituted cis-cyclopropanes in high enantio- and diastereoselectivity. Subsequently, in the presence of a broad range of primary amines, the dicarbonyl cis-cyclopropanes were efficiently and completely diastereoselectively cyclized by a Cp^*IrIII catalyst via an iterative aminative transfer hydrogen to an exquisite set of substituted 3-azabicyclo[3.1.0]hexanes.

3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., Related Products of 3032-92-6

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Inorganic compounds containing the −C≡N group are not called nitriles, but cyanides instead.3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Though both nitriles and cyanides can be derived from cyanide salts, most nitriles are not nearly as toxic. Application In Synthesis of 3032-92-6.

Li, Huan;Wang, Fang;Zhu, Shengqing;Chu, Lingling research published 《 Selective Fluoromethyl Couplings of Alkynes via Nickel Catalysis》, the research content is summarized as follows. A Ni-catalyzed intermol. carbo-fluoromethylation of alkynes with aliphatic halides and fluoromethyl halides (BrCF₂H and ICH₂F) in the presence of zinc was described, enabling the facile and selective access to a diverse range of biol. valuable CF₂H/CH₂F-incorporated alkenes with excellent regio- and stereoselectivity. Notably, merging intramol. radical cyclization with fluoromethyl coupling enabled the expedient constructions of CF₂H/CH₂F-incorporated lactones and lactams with high efficiency and selectivity. Mechanistic studies disclosed that this catalytic protocol proceeded via a radical addition to an alkyne followed by selective coupling with the fluoromethyl unit.

Application In Synthesis of 3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts