Category: 3032-92-6

Industrially, the main methods for producing nitriles are ammoxidation and hydrocyanation. 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Both routes are green in the sense that they do not generate stoichiometric amounts of salts. Safety of 4-Ethynylbenzonitrile.

Xu, Tianhao;Zhou, Xiangbing;Han, Yuhui;Zhang, Liangwei;Liu, Long;Huang, Tianzeng;Li, Chunya;Tang, Zhi;Wan, Shungang;Chen, Tieqiao research published 《 Palladium-catalyzed stereo-selective three-component cis-1,2-arylalkynylation of bicyclic alkenes with aryltriflates and terminal alkynes》, the research content is summarized as follows. Synthesis of (1S,2R,3S,4R)-2-(arylethynyl)-3-(aryl)bicyclo[2.2.1]heptanes I [R = Ph, 4-MeC₆H₄, 4-FC₆H₄, etc.; Ar = Ph, 2-MeC₆H₄, 4-MeOC₆H₄, etc.; R¹ = H, C(O)Me] via a palladium-catalyzed stereo-selective cis-1,2-arylalkynylation of bicyclic alkenes with aryl triflates and terminal alkynes was developed. This reaction showed high functional group tolerance and could be applied to the modification of bioactive mols. This three-component reaction provided a practical method for preparing the value-added bicyclo[2.2.1]heptanes derivatives

Safety of 4-Ethynylbenzonitrile, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Inorganic compounds containing the −C≡N group are not called nitriles, but cyanides instead.3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Though both nitriles and cyanides can be derived from cyanide salts, most nitriles are not nearly as toxic. HPLC of Formula: 3032-92-6.

Wang, Qiuzhu;Wang, Mengning;Wu, Qianhui;Ma, Mengtao;Zhao, Binlin research published 《 Synthesis of β-Polychlorinated Alkynes Enabled by Copper-Catalyzed Multicomponent Reaction》, the research content is summarized as follows. Functional mols. bearing polychlorinated moieties usually play versatile roles in organic synthesis and biochem. A copper-catalyzed multicomponent polychloro-carboalkynylation of alkenes presents an efficient and operationally simple approach for the synthesis of β-polychlorinated alkynes. Mechanistic experiments were conducted demonstrating that an in situ generated copper acetylide complex was the real catalyst and reactive intermediate during the copper-catalytic cycle. And enantioselective exploration demonstrated potential application for the synthesis of chiral β-polychlorinated alkynes.

HPLC of Formula: 3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Inorganic compounds containing the −C≡N group are not called nitriles, but cyanides instead.3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Though both nitriles and cyanides can be derived from cyanide salts, most nitriles are not nearly as toxic. Reference of 3032-92-6.

Wang, Xiaoshuang;Sun, Lei;Wang, Miaomiao;Maestri, Giovanni;Malacria, Max;Liu, Xiang;Wang, Yanlan;Wu, Lingang research published 《 C-I Selective Sonogashira and Heck Coupling Reactions Catalyzed by Aromatic Triangular Tri-palladium》, the research content is summarized as follows. Aromatic triangular tri-palladium cations, abbreviated as [Pd₃]⁺, have shown interesting photoelec. properties, Lewis basic character, and excellent activities in catalytic hydrogenation. Herein, authors report the highly efficient and C-I selective Sonogashira and Heck coupling reactions catalyzed by these tri-palladium complexes. Benefiting from the moderate C-I bond association energy, these tri-palladiums presented exclusive reactivities to aryl iodides over the brominated aromatics in coupling reactions. In the Sonogashira pathway, good to excellent isolated yields (71-95%) were achieved. Gram-scale reaction reached 93% of yield with palladium loading as few as 0.06 mol %. Authors also explored the electronic and steric effects for Ph alkynes and aryl iodides including heteroaromatics like thiophene, pyridine, pyrazole, and pyrazine. Similarly, yields of 71-96% were obtained for palladium loading of 1.5 mol% through catalyzed Heck coupling of aryl iodides and alkenes. The HRMS monitoring revealed that [Pd₃]⁺ maintained as whole entity during the catalytic process due to its robusness.

Reference of 3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Industrially, the main methods for producing nitriles are ammoxidation and hydrocyanation. 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Both routes are green in the sense that they do not generate stoichiometric amounts of salts. Recommanded Product: 4-Ethynylbenzonitrile.

Wang, Xuemei;Zhou, Liang;Zhang, Hongkui;Ren, Xiaoyu;Gao, Guowei;Wang, Tianli research published 《 Enantioselective γ-Addition-Driven Cascade of β,γ-Unsaturated Ketones by Ion-Pair Catalysis: Access to Chiral 1,3-Dioxolochroman Scaffolds》, the research content is summarized as follows. A highly enantioselective γ-addition-driven cascade of β,γ-unsaturated carbonyl compounds by bifunctional ion-pair catalysis was developed. With this protocol, a range of functionalized chiral 1,3-dioxolochroman derivatives I [Ar¹ = Ph, 3-FC₆H₄, 2-naphthyl, etc.; Ar² = Ph, 4-MeOC₆H₄, 3-FC₆H₄, etc.; Ar³ = Ph, 2-ClC₆H₄, 4-MeOC₆H₄, etc.] were prepared in high yields with superior stereoselectivities (>99% ee and >20:1 dr). The utility of this method was demonstrated by one-pot synthesis, scaled-up preparation, and facile transformation. Moreover, mechanistic investigations provided insights into reaction pathway and origin of chiral induction.

3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., Recommanded Product: 4-Ethynylbenzonitrile

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitriles used to be known as cyanides; the smallest organic nitrile is ethanenitrile, CH3CN, (old name: methyl cyanide or acetonitrile – and sometimes now called ethanonitrile). 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Nitriles are found in many useful compounds, including methyl cyanoacrylate, used in super glue, and nitrile rubber, a nitrile-containing polymer used in latex-free laboratory and medical gloves. Recommanded Product: 4-Ethynylbenzonitrile.

Wang, Zhenyu;Cao, Chengyao Kimmy;Tretyakov, Evgeny;Liu, Wei;Chen, Chao research published 《 A Facile Stereoselective Bis-Trifluoromethylselenolation Reaction of Alkynes with AgSeCF₃ and N-Bromosuccinimide》, the research content is summarized as follows. A facile stereoselective bis-trifluoromethylselenolation reaction of alkyne derivatives was realized for the first time. The reaction of alkyne derivatives and AgSeCF₃ was found to proceed in the presence of N-bromosuccinimide and water in THF and afforded bis-trifluoromethylselenolated products in moderate-to-excellent yields. The new methodol. enables one-pot synthesis with a broad substrate range.

3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., Recommanded Product: 4-Ethynylbenzonitrile

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Inorganic compounds containing the −C≡N group are not called nitriles, but cyanides instead.3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Though both nitriles and cyanides can be derived from cyanide salts, most nitriles are not nearly as toxic. HPLC of Formula: 3032-92-6.

Wang, Qiuzhu;Wang, Mengning;Wu, Qianhui;Ma, Mengtao;Zhao, Binlin research published 《 Synthesis of β-Polychlorinated Alkynes Enabled by Copper-Catalyzed Multicomponent Reaction》, the research content is summarized as follows. Functional mols. bearing polychlorinated moieties usually play versatile roles in organic synthesis and biochem. A copper-catalyzed multicomponent polychloro-carboalkynylation of alkenes presents an efficient and operationally simple approach for the synthesis of β-polychlorinated alkynes. Mechanistic experiments were conducted demonstrating that an in situ generated copper acetylide complex was the real catalyst and reactive intermediate during the copper-catalytic cycle. And enantioselective exploration demonstrated potential application for the synthesis of chiral β-polychlorinated alkynes.

HPLC of Formula: 3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitriles used to be known as cyanides; the smallest organic nitrile is ethanenitrile, CH3CN, (old name: methyl cyanide or acetonitrile – and sometimes now called ethanonitrile). 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Nitriles are found in many useful compounds, including methyl cyanoacrylate, used in super glue, and nitrile rubber, a nitrile-containing polymer used in latex-free laboratory and medical gloves. Formula: C9H5N.

Uchikura, Tatsuhiro;Aruga, Kureha;Suzuki, Riku;Akiyama, Takahiko research published 《 Enantioselective Friedel-Crafts Alkylation Reaction of Pyrroles with N-Unprotected Alkynyl Trifluoromethyl Ketimines》, the research content is summarized as follows. Developed herein is an enantioselective Friedel-Crafts alkylation reaction of N-unprotected alkynyl trifluoromethyl ketimines with pyrroles catalyzed by chiral phosphoric acid to furnish chiral primary α-trifluoromethyl-α-(2-pyrrolyl)propargylamines with high enantioselectivity. Transformation of the alkynyl group of the adducts afforded optically active α-trifluoromethylated amines bearing various substituents such as alkyl, alkenyl, enyne, and triazole without loss of optical purity.

Formula: C9H5N, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Inorganic compounds containing the −C≡N group are not called nitriles, but cyanides instead.3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Though both nitriles and cyanides can be derived from cyanide salts, most nitriles are not nearly as toxic. Electric Literature of 3032-92-6.

Uema, Seiya;Saito, Kodai;Yamada, Tohru research published 《 Silver-Catalyzed Carbon Dioxide Fixation on Alkynylindoles》, the research content is summarized as follows. A silver-catalyzed carbon dioxide fixation reaction into 2-alkynylindole derivatives I [R¹ = cyclohexyl, Ph, thiophen-2-yl, etc.; R² = H, Me; R³ = H, F, OMe, etc.; R⁴ = H, OMe; -R³R⁴– = -OCH₂O-] was developed to afford tricyclic indoles II. Carbon dioxide was selectively fixed on the N atom of the indole, and only 6-endo-dig cyclization proceeded under mild reaction conditions. Carboxylation on C3 of the indole was not observed This method was applicable for a variety of 2-alkynylindoles I, and the corresponding products II were obtained in high yields without the production of side products.

3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., Electric Literature of 3032-92-6

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitriles are found in many useful compounds. Nitrile rubber is also widely used as automotive and other seals since it is resistant to fuels and oils. Organic compounds containing multiple nitrile groups are known as cyanocarbons. 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Nitriles are found in many useful compounds. One of the most common occurrences of nitriles is in Nitrile rubber. Quality Control of 3032-92-6.

Wang, Fu-Li;Yang, Chang-Jiang;Liu, Ji-Ren;Yang, Ning-Yuan;Dong, Xiao-Yang;Jiang, Ruo-Qi;Chang, Xiao-Yong;Li, Zhong-Liang;Xu, Guo-Xiong;Yuan, Dai-Lei;Zhang, Yu-Shuai;Gu, Qiang-Shuai;Hong, Xin;Liu, Xin-Yuan research published 《 Mechanism-based ligand design for copper-catalysed enantioconvergent C(sp³)-C(sp) cross-coupling of tertiary electrophiles with alkynes》, the research content is summarized as follows. A general copper-catalyzed enantioconvergent C(sp³)-C(sp) cross-coupling of diverse racemic tertiary alkyl halides RX [R = 1-cyclohexyl-1-[(naphthalen-1-yl)carbamoyl]ethyl, 1-phenyl-1-(phenylcarbamoyl)propyl, 1-[(4-bromophenyl)carbamoyl]-1-phenylpropyl, etc.; X = Cl, Br] and I (R¹ = Et, cyclopropyl, benzyl, etc.; R² = Et, Ph, 3-bromophenyl, etc.) with terminal alkynes R³CCH (R³ = Ph, cyclohexen-1-yl, thiophen-2-yl, etc.) (87 examples) was demonstrated. Key to the success is the rational design of chiral anionic N,N,N-ligands, e.g., II (R⁴ = t-butylphenyl) tailor-made for the computationally predicted outer-sphere radical group transfer pathway. This protocol provides a practical platform for the construction of chiral C(sp³)-C(sp/sp²/sp³) bonds, allowing for expedient access to an array of synthetically challenging quaternary carbon building blocks of interest in organic synthesis and related areas.

Quality Control of 3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Inorganic compounds containing the −C≡N group are not called nitriles, but cyanides instead.3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Though both nitriles and cyanides can be derived from cyanide salts, most nitriles are not nearly as toxic. Product Details of C9H5N.

Skrodzki, Maciej;Ortega Garrido, Victor;Csaky, Aurelio G.;Pawluc, Piotr research published 《 Searching for highly active cobalt catalysts bearing Schiff base ligands for Markovnikov-selective hydrosilylation of alkynes with tertiary silanes》, the research content is summarized as follows. The search for simple and easy-to-synthesize ligands for bench stable cobalt (pre)catalysts that would ensure high activity and selectivity in alkyne hydrosilylation reactions is an interesting current challenge. Herein, we report that a cobalt(II) complex bearing pyrimidine-imine-2H-imidazole ligand activated by LiHBEt₃ exhibits not only high catalytic activity, but also unprecedented tolerance towards tertiary silanes in highly regioselective Markovnikov hydrosilylation of aliphatic and aromatic terminal alkynes to give α-vinylsilanes. In addition, a variety of 1-aryl-2-(trimethylsilyl)acetylenes have been hydrosilylated efficiently by diphenylsilane in the presence of [Co(L)Cl₂]/LiHBEt₃ catalytic system to yield (E)-1-aryl-1,2-bis(silyl)ethenes with high selectivity. Such selectivity is very rarely observed for cobalt-catalyzed hydrosilylation of silylacetylenes.

Product Details of C9H5N, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts