Category: 3032-92-6

Nitriles are found in many useful compounds. Nitrile rubber is also widely used as automotive and other seals since it is resistant to fuels and oils. Organic compounds containing multiple nitrile groups are known as cyanocarbons. 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Nitriles are found in many useful compounds. One of the most common occurrences of nitriles is in Nitrile rubber. COA of Formula: C9H5N.

Fang, Fang;Zheng, Haolin;Mao, Guojiang;Chen, Shanping;Deng, Guo-Jun research published 《 Metal- and Solvent-Free Synthesis of Tetrahydrobenzo[c]carbazolones through NaI-Catalyzed Formal [4+2] Annulation》, the research content is summarized as follows. A novel strategy for the preparation of functional carbazoles through NaI-catalyzed formal [4+2] annulation of 2-(indol-3-yl)cyclohexanones and alkynes/alkenes was developed. The present approach started from easily available raw materials and provided a variety of tetrahydrobenzo[c]carbazolones in satisfactory yields under metal- and solvent-free conditions. The products could be further transformed into structurally valuable carbazole-based conjugated derivatives

COA of Formula: C9H5N, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Inorganic compounds containing the −C≡N group are not called nitriles, but cyanides instead.3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Though both nitriles and cyanides can be derived from cyanide salts, most nitriles are not nearly as toxic. Name: 4-Ethynylbenzonitrile.

Cui, Jian-Fang;Yu, Qiong;O, Wa-Yi;Huang, Li-Wu;Yang, Bin;Wong, Man-Kin research published 《 Synthesis of 1H-isoindoliums by electrophile-mediated cascade cyclization/iodination of propargylamine-based 1,6-diynes》, the research content is summarized as follows. A highly regio- and chemoselective synthesis of 1H-isoindoliums I [R¹ = Ph, 3-MeC₆H₄, 3-thienyl, etc.; R² = CH₂, CH(Me), O; R³ = H, 6-Me, 5-Cl, 6-Cl, 6-MeO, 6-CF₃] through a facile and novel cascade cyclization reaction of propargylamine-based 1,6-diynes under mild conditions had been developed. Different functional groups were compatible under the optimized reaction conditions, giving the corresponding products in up to 94% yields. Upon treatment with a base, the alkyne moiety of 1H-isoindoliums could be further transformed to allenes II [R⁴ =CH₂, O; R⁵ = Ph, 4-FC₅H₄, 4-NCC₆H₄; R⁶ = H] in excellent yields.

Name: 4-Ethynylbenzonitrile, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitriles are found in many useful compounds. Nitrile rubber is also widely used as automotive and other seals since it is resistant to fuels and oils. Organic compounds containing multiple nitrile groups are known as cyanocarbons. 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Nitriles are found in many useful compounds. One of the most common occurrences of nitriles is in Nitrile rubber. Computed Properties of 3032-92-6.

Ding, Ding;Xu, Liang;Wei, Yu research published 《 The Synthesis of α-Keto Acetals from Terminal Alkynes and Alcohols via Synergistic Interaction of Organoselenium Catalysis and Electrochemical Oxidation》, the research content is summarized as follows. Herein, an unprecedented electrochem. approach for the synthesis of α-keto acetals R¹C(O)CH(OR)₂ [R¹ = C₆H₅, 3-MeC₆H₄, 3,5-di-FC₆H₃, etc.; R² = Me, Et, n-Pr] was established, from readily available terminal alkynes and alcs. By merging the electrochem. and organoselenium-catalyzed processes, the desired products were obtained at room temperature in the absence of basic or metallic additives, with carbonyl and acetal motifs incorporated simultaneously across the triple bonds in a single operation.

3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., Computed Properties of 3032-92-6

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitriles are found in many useful compounds. Nitrile rubber is also widely used as automotive and other seals since it is resistant to fuels and oils. Organic compounds containing multiple nitrile groups are known as cyanocarbons. 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Nitriles are found in many useful compounds. One of the most common occurrences of nitriles is in Nitrile rubber. SDS of cas: 3032-92-6.

Duan, Yongjie;Liang, Kun;Yin, Hongquan;Chen, Fu-Xue research published 《 Dithiocyanation of Alkynes with N-Thiocyanato-dibenzenesulfonimide and Ammonium Thiocyanate》, the research content is summarized as follows. An efficient dithiocyanation of alkynes with N-thiocyanato-dibenzenesulfonimide (NTSI) as the SCN+ cation and ammonium thiocyanate as the SCN- anion sources to form 1-(1,2-Dithiocyanato-2-(aryl)vinyl)-benzenes I [R¹ = Me, H, F, etc.; R² = t-Bu, 4-MeC₆H₄, 3-MeOC₆H₄, etc.] was developed. Highly active electrophilic reagent NTSI could react with various types of alkynes to build C(sp²)-SCN bond to provide a variety of dithiocyanato olefin compounds under simple and mild conditions. Trace amount of water was beneficial to the dissociation of ammonium thiocyanate, which makes the SCN- anion easier to participate in the reaction. The protocol owned a broad substrates scope including terminal and internal, alkyl and aryl alkynes, excellent functional group tolerance and good regioselectivity.

SDS of cas: 3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Inorganic compounds containing the −C≡N group are not called nitriles, but cyanides instead.3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Though both nitriles and cyanides can be derived from cyanide salts, most nitriles are not nearly as toxic. Recommanded Product: 4-Ethynylbenzonitrile.

Chen, Peng;Wang, Zhi-Yong;Wang, Jia-Xin;Peng, Xiao-Shui;Wong, Henry N. C. research published 《 Remote C(sp³)-H activation: palladium-catalyzed intermolecular arylation and alkynylation with organolithiums and terminal alkynes》, the research content is summarized as follows. A 1,4-palladium shift is regarded as one of the solutions towards the challenging remote C(sp³)-H activation. Herein, authors report two efficient remote C(sp³)-H activation protocols involving palladium-catalyzed C(sp³)-C(sp²) and C(sp³)-C(sp) cross-coupling with aryllithium reagents and terminal alkynes as key coupling partners, resp. More than 50 examples with acceptable to high yields, good functional group tolerance, and high regioselectivities are presented. The practicality of the reaction is demonstrated in a gram-scale manner.

3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., Recommanded Product: 4-Ethynylbenzonitrile

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitrile is any organic compound with a −C≡N functional group. 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile.The prefix cyano- is used interchangeably with the term nitrile in literature. Reference of 3032-92-6.

Cleemann, Felix;Kum-Cheung, Wendy Loa;Karuso, Peter research published 《 Combinatorial synthesis of new fluorescent scaffolds using click chemistry》, the research content is summarized as follows. Azides and acetylenes are bio-orthogonal functional groups that can be readily coupled using copper(I)- or ruthenium(II)- catalyzed 1,3-dipolar cycloaddition reactions. Using non-fluorescent aromatic azides and aromatic acetylenes, covering a range of electron rich and poor building blocks, the Huisgen cycloaddition afford 1,4-disubstituted or 1,5-disubstituted 1,2,3-triazoles. Using a combinatorial approach by running reaction in parallel in polypropylene 96-well plates we discovered several new fluorescent 1,2,3-triazoles scaffolds. These compounds show diverse interactions with biomols. that could find applications in biol. in, for example, fluorescence microscopy or biomol. quantification.

Reference of 3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Industrially, the main methods for producing nitriles are ammoxidation and hydrocyanation. 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Both routes are green in the sense that they do not generate stoichiometric amounts of salts. Application In Synthesis of 3032-92-6.

Cai, Chen;Lu, Yi;Yuan, Chengcheng;Fang, Zheng;Yang, Xiaobing;Liu, Chengkou;Guo, Kai research published 《 Metal-Free C-C Cross Coupling: Electrosynthesis of Azaheterocycles through Anodic Oxidation Cyclization of 1,6-Enynes》, the research content is summarized as follows. A straightforward synthesis of azaheterocycles has been developed through electrochem. aerobic oxidation cyclization using a user-friendly undivided electrolytic cell at room temperature under catalyst-free conditions. This green and practical electrosynthesis strategy features good functional group, diverse electronic and steric properties tolerance. Based on a series of mechanistic investigation, including isotope labeling, singlet oxygen inhibiting, superoxide radical anion inhibiting, radical-trapping, cyclic voltammetry and controlled potential electrolysis experiments, a possible N-centered radical-initiated mechanism was proposed.

Application In Synthesis of 3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitrile groups in organic compounds can undergo a variety of reactions depending on the reactants or conditions. 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. A nitrile group can be hydrolyzed, reduced, or ejected from a molecule as a cyanide ion. Product Details of C9H5N.

Chatterjee, Shrestha;Acharyya, Ranjan Kumar;Pal, Pratik;Nanda, Samik research published 《 Synthetic studies towards naturally occurring γ-(Z)/(E)-alkylidenebutenolides through bimetallic cascade cyclization and an adventitious photoisomerization method》, the research content is summarized as follows. A general and flexible visible light-induced photoisomerization method of γ-(Z)-alkylidenebutenolides to their corresponding E-components was reported in this article. Initially, a series of naturally occurring enantiopure γ-(Z)-alkylidenebutenolides was synthesized by employing a “Pd-Cu” bimetallic cascade cyclization protocol. In the later part, the synthesized γ-(Z)-alkylidenebutenolides were photoisomerized in the presence of a triplet photosensitizer to γ-(E)-alkylidenebutenolides in reasonably acceptable yields. Total synthesis of goniobutenolides, hygrophorones, ramariolide D, melodorinols/acetyl-melodorinols, versicolactones, and phomopsolidones was achieved by employing the developed methods.

3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., Product Details of C9H5N

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Electric Literature of 3032-92-6,Some common heterocyclic compound, 3032-92-6, name is 4-Ethynylbenzonitrile, molecular formula is C9H5N, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

General procedure: Polymer supported metal catalyst (25mg, 21×10-3mmol) in water (5mL) was taken in a 50mL round bottom flask. Then phenylacetylene (1mmol), sodium azide (1.2mmol) and benzyl bromide (1mmol) were added and stirred at room temperature for 180 min. After the completion of the reaction, the catalyst was filtered off and washed with water followed by acetone and dried in oven. The filtrate was extracted with ethyl acetate (3×20ml) and the combined organic layers were dried with anhydrous Na2SO4 by vacuum. All the prepared compounds were confirmed by 1H and 13C NMR.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 4-Ethynylbenzonitrile, its application will become more common.

Reference:
Article; Molla, Rostam Ali; Roy, Anupam Singha; Ghosh, Kajari; Salam, Noor; Iqubal, Md Asif; Tuhina; Islam, Sk Manirul; Journal of Organometallic Chemistry; vol. 776; (2015); p. 170 – 179;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 3032-92-6, name is 4-Ethynylbenzonitrile, This compound has unique chemical properties. The synthetic route is as follows., HPLC of Formula: C9H5N

Sequentially adding a catalyst in the reaction bottle (14.0 mg, 0.025 millimole, 5mol %), cesium carbonate (32.6 mg, 1.0 mmol), 4-ethynyl phenyl nitrile (63.6 mg, 0.5 mmol),N,N-dimethylformamide(3 ml), into the carbon dioxide, in the 50 C, reaction under normal pressure 16 hours. Reaction cooling to room temperature, diluted with water, acidified with hydrochloric acid, diethyl ether extraction, washing with saturated sodium chloride for ether level, dry anhydrous sodium sulfate, obtained product is vacuum to remove the solvent, the yield is 93%

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 3032-92-6.

Reference:
Patent; Suzhou University; Sun, Hongmei; Zhu, Fan; Lu, Bing; (10 pag.)CN105585473; (2016); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts