Category: 3032-92-6

Inorganic compounds containing the −C≡N group are not called nitriles, but cyanides instead.3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Though both nitriles and cyanides can be derived from cyanide salts, most nitriles are not nearly as toxic. Recommanded Product: 4-Ethynylbenzonitrile.

Zhang, Zhansong;Song, Qingmin;Feng, Chengjie;Wang, Zikun;Zhao, Wanjun;Ning, Yongquan;Wu, Yong research published 《 The sulfinylsulfonation of alkynes for β-sulfinyl alkenylsulfone》, the research content is summarized as follows. Here the sulfinylsulfonation of alkynes to afford β-sulfinyl alkenylsulfone products RS(O)C(R¹)=C(R²)SO₂R [R = Me, Ph, 4-MeC₆H₄, etc.; R¹ = n-Bu, cyclohexyl, Ph, etc.; R² = H, Me, Br, etc.] with a broad substrate scope, excellent functional group compatibility and high yield was reported. Moreover, the sulfinylsulfonation reaction of enyne could also be realized for constructing functionalized carbo- and heterocycles, e.g., I through a radical cascade cyclization process.

Recommanded Product: 4-Ethynylbenzonitrile, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitriles are found in many useful compounds. Nitrile rubber is also widely used as automotive and other seals since it is resistant to fuels and oils. Organic compounds containing multiple nitrile groups are known as cyanocarbons. 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Nitriles are found in many useful compounds. One of the most common occurrences of nitriles is in Nitrile rubber. Application of C9H5N.

Zhang, Zhen;Li, Jie;Chen, Hao;Huang, Jing;Song, Xiaojuan;Tu, Zheng-Chao;Zhang, Zhang;Peng, Lijie;Zhou, Yang;Ding, Ke research published 《 Design, Synthesis, and Biological Evaluation of 2-Formyl Tetrahydronaphthyridine Urea Derivatives as New Selective Covalently Reversible FGFR4 Inhibitors》, the research content is summarized as follows. Aberrant FGF19/FGFR4 signaling is an oncogenic driver force for the development of human hepatocellular carcinoma (HCC). A series of 2-formyl tetrahydronaphthyridine urea derivatives I (R = 2-phenylethynyl, 2-(pyridin-2-yl)ethynyl, 2-(3-methoxyphenyl)ethyl, etc.; R¹ = F, propan-2-yloxidanyl, cyclopentylaminyl, etc.) and II was designed and synthesized as new covalently reversible inhibitors of FGFR4. The representative compound II (R = 2-(pyridin-3-yl)ethynyl) (III) exhibited an IC₅₀ value of 5.4 nM against FGFR4 and demonstrated extraordinary kinome selectivity. Compound III also exhibited good oral pharmacokinetic properties with an AUC_(0-t) value of 38 950.06 h*ng/mL, a T_1/2 value of 3.06 h, and an oral bioavailability of 50.97%, at an oral dose of 25 mg/kg in Sprague-Dawley (SD) rats. Furthermore, compound III induced significant tumor regressions in a xenograft mouse model of Hep3B2.1-7 HCC cancer cells without an obvious sign of toxicity upon 30 mg/kg oral administration. Compound III may serve as a promising lead compound for further anticancer drug development.

3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., Application of C9H5N

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitrile is any organic compound with a −C≡N functional group. 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile.The prefix cyano- is used interchangeably with the term nitrile in literature. Reference of 3032-92-6.

Zheng, Changge;Ma, Mingyu;Huang, Shuai;Jiang, Chao;Liu, Yang;Fu, Yingying;Zhao, Kui;Feng, Ruilong;Hong, Jianquan research published 《 Stereoretentive trifluoromethylthiolation of (E)-styrylboronic acid with AgSCF₃ or N-trifluoromethylthiosuccinimide》, the research content is summarized as follows. A stereoretentive trifluoromethylthiolation of styrylboronic acids with AgSCF₃ or N-trifluoromethylthiosuccinimide has been developed under mild reaction conditions. This synthetic method for vinyl trifluoromethyl thioethers possesses good functional group tolerance, high yield and excellent stereoselectivity with AgSCF₃ as the SCF₃ source. The stereospecificity of the reaction could been achieved through the trifluoromethylthiolation of β-styrylboronic acids with N-trifluoromethylthiosuccinimide.

Reference of 3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Industrially, the main methods for producing nitriles are ammoxidation and hydrocyanation. 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Both routes are green in the sense that they do not generate stoichiometric amounts of salts. Formula: C9H5N.

Zheng, Zhipeng;He, Jiali;Ma, Qianru;Zhang, Yumeng;Liu, Yan;Tang, Guo;Zhao, Yufen research published 《 Photoredox/copper-catalyzed coupling of terminal alkynes with P(O)SH compounds leading to alkynyl phosphorothioates》, the research content is summarized as follows. The direct construction of a C(sp.)-S-P(O) moiety from unactivated terminal alkynes remains highly challenging. Alkynyl phosphorothioates are obtained by coupling terminal alkynes and P(O)SH. Using com. available and inexpensive Ru(bpy)₃Cl₂ and copper as a catalyst, this cross dehydrogenative coupling reaction is first performed under photoirradiation Direct use of stable P(O)SH and terminal alkynes without the need to prepare unstable S-X and P-X derivatives represents a prominent advantage of this method. More attractively, this operationally simple reaction avoids the use of odorous thiols and poisonous alkynyl bromides.

3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., Formula: C9H5N

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitriles used to be known as cyanides; the smallest organic nitrile is ethanenitrile, CH3CN, (old name: methyl cyanide or acetonitrile – and sometimes now called ethanonitrile). 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Nitriles are found in many useful compounds, including methyl cyanoacrylate, used in super glue, and nitrile rubber, a nitrile-containing polymer used in latex-free laboratory and medical gloves. Formula: C9H5N.

Yusuf, Mohammad;Hira, Shamim Ahmed;Park, Kang Hyun research published 《 Light-Harvesting Novel Hierarchical Porous Cu₉S₅-MnWO₄ Hybrid Structures in Photocatalytic Oxidative Homocoupling of Alkynes and Amines》, the research content is summarized as follows. The discovery of light-harvesting materials for use in photocatalytic organic reactions has recently attracted attention, indicating the potential for utilizing renewable energy sources. A hybrid semiconductor (SC)-SC structure, Cu₉S₅-MnWO₄, was synthesized using a simple, efficient method. The novel hierarchical porous Cu₉S₅-MnWO₄ hybrid structures were then applied in the photocatalysis of oxidative homocoupling of alkynes and amines. The design of a heterogeneous catalyst based on a porous, SC-SC hybrid structure and low-cost Cu should generate interest in the fabrication and modification of photocatalysts for a wide range of applications.

Formula: C9H5N, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitrile is any organic compound with a −C≡N functional group. 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile.The prefix cyano- is used interchangeably with the term nitrile in literature. Electric Literature of 3032-92-6.

Zeng, Jiajun;Li, Jianying;Huang, Bin;Li, Jiajia;Cai, Mingzhong research published 《 A practical access to 1,2-dicarbonyls via oxidation of alkynes catalyzed by gold(I) immobilized on MCM-41》, the research content is summarized as follows. The heterogeneous gold(I)-catalyzed oxidation of alkynes was achieved by using 2,3-dichloropyridine N-oxide as oxidant and MCM-41-anchored diphenylphosphine-gold(I) complex [MCM-41-Ph₂P-AuNTf₂] as the catalyst under mild and acid-free conditions, yielding diverse 1,2-dicarbonyls in good to excellent yields with easy recycling of the gold catalyst. The developed method is applicable to a wide variety of alkynes including internal or terminal alkynes, alkynyl ethers or thioethers and ynamides, and can tolerate a wide range of functional groups.

Electric Literature of 3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Industrially, the main methods for producing nitriles are ammoxidation and hydrocyanation. 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Both routes are green in the sense that they do not generate stoichiometric amounts of salts. Electric Literature of 3032-92-6.

Zeng, Meng-Qiang;Feng, Ke-Xin;Hu, Bo-Lun;Tu, Hai-Yong;Zhang, Xing-Guo research published 《 Ni-Catalyzed Reductive Arylalkenylation of Alkynes for the Selective Synthesis of Polysubstituted Naphthalenes》, the research content is summarized as follows. A Ni-catalyzed reductive arylalkenylation of alkynes with 1-bromo-2-(2-chlorovinyl)arenes in the presence of zinc powder has been developed. This base-free cyclization provides a novel protocol for the selective synthesis of 2-trifluoromethyl naphthalenes and Et 2-naphthoates from simple starting materials in moderate to good yields with excellent tolerance of functional groups.

Electric Literature of 3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitrile is any organic compound with a −C≡N functional group. 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile.The prefix cyano- is used interchangeably with the term nitrile in literature. Application of C9H5N.

Zhang, Xitao;Zhang, Sheng;Li, Shihong;Feng, Xiujuan;Yamamoto, Yoshinori;Bao, Ming research published 《 Three-component addition of terminal alkynes, carboxylic acids, and tert-butyl hypochlorite》, the research content is summarized as follows. This paper described the unprecedented three-component addition of terminal alkynes, carboxylic acids, and tert-Bu hypochlorite. This new type of addition proceeds smoothly to produce gem-dichloroalkane derivatives in satisfactory to excellent yields via successive two-time additions under mild conditions. The synthetically useful functional groups, such as Cl, Br, CN, and NO₂, remained intact in the final products.

3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., Application of C9H5N

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nitriles used to be known as cyanides; the smallest organic nitrile is ethanenitrile, CH3CN, (old name: methyl cyanide or acetonitrile – and sometimes now called ethanonitrile). 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Nitriles are found in many useful compounds, including methyl cyanoacrylate, used in super glue, and nitrile rubber, a nitrile-containing polymer used in latex-free laboratory and medical gloves. Recommanded Product: 4-Ethynylbenzonitrile.

Yang, Bin;Yang, Junfeng;Zhang, Junliang research published 《 Synthesis of Axially Chiral Anilides Enabled by a Palladium/ Ming-Phos-Catalyzed Desymmetric Sonogashira Reaction》, the research content is summarized as follows. Atropisomeric anilides are one of important C-N axially chiral compounds Compared with the N-terminal functionalization to prepare such compounds, C-terminal functionalization strategies have been rarely reported. Authors describe herein an efficient synthesis of axially chiral anilides enabled by Pd-catalyzed desym. Sonogashira cross-coupling reactions with the use of a newly identified Ming-Phos. Moderate to high yields with high enantioselectivities (up to 98% ee) were obtained.

3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., Recommanded Product: 4-Ethynylbenzonitrile

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Industrially, the main methods for producing nitriles are ammoxidation and hydrocyanation. 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Both routes are green in the sense that they do not generate stoichiometric amounts of salts. Product Details of C9H5N.

Wu, Jianglong;Wang, Chenyu;Wang, Zhongjie;Li, Hongjun;Liu, Ruyan;Wang, Yan;Zhou, Pengsheng;Li, Dianjun;Yang, Jinhui research published 《 Base/B₂pin₂-Mediated Iodofluoroalkylation of Alkynes and Alkenes》, the research content is summarized as follows. A base/B₂pin₂-mediated iodofluoroalkylation of alkynes and a part of alkenes, using Et difluoroiodoacetate (ICF₂CO₂Et) or IC_nF_2n+1(n = 3, 4, 6) as difluoroacetylating or perfluoroalkylating reagent, is disclosed. The reaction proceeds under mild conditions, and iododifluoroalkylation, hydrodifluoroalkylation and several perfluoroalkylation products were generated from alkynes or alkenes. Notably, this methodol. provides a simple access to difluoroalkylated and perfluoroalkylated organic compounds starting from simple alkynes or alkenes.

Product Details of C9H5N, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts