Category: 26830-96-6

Introduction of a new synthetic route about 26830-96-6

The synthetic route of 26830-96-6 has been constantly updated, and we look forward to future research findings.

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 26830-96-6, name is 2-Amino-4-methylbenzonitrile belongs to nitriles-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. Product Details of 26830-96-6

Combine [L-FLUORO-2-NITRO-BENZENE] (5.34 g, 37.83 mmol), 2-amino-4-methyl- benzonitrile (5.00 g, [37.] 83 [MMOL),] lithium hydroxide monohydrate (3.17 g, 75.66 mmol) and DMSO (70.0 ml) and stir at [55 C. AFER] 16 hours, cool to ambient temperature, pour the mixture onto ice chips and stir. After 1 hour, remove the resulting yellow precipitate by vacuum filtration. Dry the precipitate under vacuum, recrystallize in ethanol to give 5.15 g (54%) of fine, amber colored needles: mp 162-164 C ; mass spectrum (ion spray): m/z = 254.0 (M+1).

The synthetic route of 26830-96-6 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; ELI LILLY AND COMPANY; WO2004/14895; (2004); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Analyzing the synthesis route of 26830-96-6

The chemical industry reduces the impact on the environment during synthesis 2-Amino-4-methylbenzonitrile. I believe this compound will play a more active role in future production and life.

Reference of 26830-96-6, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 26830-96-6, name is 2-Amino-4-methylbenzonitrile, This compound has unique chemical properties. The synthetic route is as follows.

EXAMPLE 120 4-(2-Cyano-5-methylanilino)-2-(3-pyridinyl)-6-(trifluoromethyl)pyrimidine The title compound was prepared from a mixture of 4-chloro-2-(3-pyridinyl)-6-(trifluoromethyl)pyrimidine (50 mg, 0.193 mmol) and 2-cyano-5-methylaniline (38 mg, 0.290 mmol) similar to Example 117 and isolated as a yellow solid (8 mg, 12%). 1H NMR (CDCl3): 9.62-9.61 (m, 1H), 8.75-8.69 (m, 2H), 8.08 (s, 1H), 7.62 (s, 1H), 7.60 (d, J=8.1 Hz, 1H), 7.46-7.41 (m, 1H), 7.12 (dd, J=0.9, 8.1 Hz, 1H), 7.00 (s, 1H), 2.52 (s, 3H).

The chemical industry reduces the impact on the environment during synthesis 2-Amino-4-methylbenzonitrile. I believe this compound will play a more active role in future production and life.

Reference:
Patent; Cytovia, Inc.; US2003/69239; (2003); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts