Category: 1953-99-7

Electric Literature of 1953-99-7, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 1953-99-7, name is 3,4,5,6-Tetrachlorobenzene-1,2-dicarbonitrile belongs to nitriles-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.

Tetrachlorophthalonitrile (26.6 parts by weight),m-mercaptobenzoic acid (15.4 parts by weight),To a solution of dimethylformamide (200 parts by weight),Add potassium carbonate (15 parts by weight)The reaction was allowed to proceed for 1 hour at room temperature.Subsequently, thionyl chloride (50 parts by weight) was added and reacted at 70 C. for 1 hour. After cooling to room temperature, 1-methoxy-2-propanol (10 parts by weight) was added, and the mixture was further heated to reflux for 4 hours. .After completion of the reaction, liquid separation with ethyl acetate and 1N aqueous hydrochloric acid was performed.The organic layer was concentrated and purified by silica gel column chromatography. Subsequently, sodium tungstate for the purified sample(5 parts by weight), hydrogen peroxide (30%, 6.8 parts by weight) acetic acid(5 parts by weight) and ethanol (50 parts by weight) were added and stirred at 50 C. for 5 hours. After completion of the reaction, separation and purification by silica gel column chromatography gave Intermediate A-103 (10 parts by weight).

The synthetic route of 3,4,5,6-Tetrachlorobenzene-1,2-dicarbonitrile has been constantly updated, and we look forward to future research findings.

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 1953-99-7, name is 3,4,5,6-Tetrachlorobenzene-1,2-dicarbonitrile, This compound has unique chemical properties. The synthetic route is as follows., Computed Properties of C8Cl4N2

Under nitrogen gas, 4,5-dichlorophthalonitrile (5.0 mmol), Ethyl vanillate (7.5 mmol), K2CO3 (50.0 mmol) was dissolved in 30 ml of anhydrous DMF and refluxed at 100 for 12 hours. When the reaction was complete, the reaction solution was slowly dropped on ice-water in a dropwise manner. The precipitate was filtered off under reduced pressure, washed with distilled water, and the dried crude product was purified by column chromatography (eluent: MC: MeOH = 15: 1)

According to the analysis of related databases, 1953-99-7, the application of this compound in the production field has become more and more popular.

Reference of 1953-99-7,Some common heterocyclic compound, 1953-99-7, name is 3,4,5,6-Tetrachlorobenzene-1,2-dicarbonitrile, molecular formula is C8Cl4N2, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

With molar ratio: tetrachlorophthalonitrile, anhydrous potassium fluoride, N, N-dimethylformamide = 1.0: 4.0: 20.Tetrachlorophthalic phthalonitrile, anhydrous potassium fluoride, N, N-dimethylformamide into chemical reactor, with stirring by increasing the temperature tetrachloro phthalonitrile, anhydrous potassium fluoride was dissolved in N, N-dimethylformamide and the temperature was raised to 110 , maintaining this temperature for 7 hours the stirring was stopped after the reaction, cooling to room temperature, to obtain a liquid mixture; chemical reactor a liquid mixture in a distillation column, the distillate is tetrafluorophthalonitrile, forthwith fed into the dryer, drying at a temperature of 60 for 2.0 hours and then was fed into the drying mill, pulverized into a powder that is finished.

The synthetic route of 1953-99-7 has been constantly updated, and we look forward to future research findings.

Application of 1953-99-7,Some common heterocyclic compound, 1953-99-7, name is 3,4,5,6-Tetrachlorobenzene-1,2-dicarbonitrile, molecular formula is C8Cl4N2, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

3,4,5,6-tetrachlorophthalonitrile (5 g), 2-isopropylphenol (2.5608 g), K2CO3 (3.898 g), and N,N-dimethylformamide (50 ml) are put in a 100 ml flask and then stirred while heated at 50¡ã C. When a reaction is complete, an extraction is performed with EA (ethyl acetate). After the extraction, a liquid column-purified through column chromatography with EA/hexane is concentrated to obtain a solid, and the solid is vacuum-dried, obtaining a compound according to Synthesis Example 6.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 3,4,5,6-Tetrachlorobenzene-1,2-dicarbonitrile, its application will become more common.

Reference:
Patent; Samsung SDI Co., Ltd.; PAK, Chae Won; SEO, Hye Won; SHIN, Myoung Youp; JEONG, Eui Soo; CHOI, Seung Jib; (35 pag.)US2017/107224; (2017); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Adding a certain compound to certain chemical reactions, such as: 1953-99-7, name is 3,4,5,6-Tetrachlorobenzene-1,2-dicarbonitrile, belongs to nitriles-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 1953-99-7, Application In Synthesis of 3,4,5,6-Tetrachlorobenzene-1,2-dicarbonitrile

To a 100 ml flask were added 3,4,5,6-tetrachlorophthalonitrile (5 g), 2,6-dibromophenol (2.45 g), K2CO3 (3.9 g) and N,N-dimethylformamide And the mixture was stirred while heating to 70 ¡ã C. After completion of the reaction, the reaction mixture is extracted with EA (ethyl acetate). After extraction and concentration, a solid can be obtained. The resulting solid is dissolved in a small amount of dichloromethane, washed several times with hexane, filtered and vacuum dried to obtain 3,4,6-trichloro-5-(2,6-dibromo-phenoxy)-phthalonitrile.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 3,4,5,6-Tetrachlorobenzene-1,2-dicarbonitrile, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; Samsung SDI Co., Ltd; Seo Hye-won; Shin Myeong-yeop; Jeong Ui-su; Han Gyu-seok; (56 pag.)KR2019/11995; (2019); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 1953-99-7, name is 3,4,5,6-Tetrachlorobenzene-1,2-dicarbonitrile, This compound has unique chemical properties. The synthetic route is as follows., category: nitriles-buliding-blocks

Into a boiling solution of 0.2 g of lithium in 50 mL of anhydrous 1-hexanol was added 1.0 g (2.6 mmol) of compound 3, 0.70 g (2.6 mmol) of compound 4, the mixture was maintained for 4 h, 1.4 g (2.0 mmol) of complex 1 was added, and the mixture was maintained for 2 h more. The solvent was distilled off, the reaction mass was dispersed in 50 mL of 10percent solution of acetic cid in acetone, the precipitate was filtered off, washed with 20 mL of 10percent ammonia solution, 100 mL of acetonitrile, 50 mL of water, and dried. Complexes 5?7 were treated with dichloromethane in a Soxhlet extractor, the extract was chromatographed on a column packed with silica gel Kieselgel 60 (Merck) (eluent dichloromethane?THF, 50 : 1 v/v). There with the mixture divided in three zones containing complexes 5?7 respectively. The complexes are dark-green powders well soluble in toluene, chloroform, dichloromethane, sparingly soluble in acetone, DMF.

According to the analysis of related databases, 1953-99-7, the application of this compound in the production field has become more and more popular.

Reference:
Article; Galanin; Shaposhnikov; Russian Journal of Organic Chemistry; vol. 51; 5; (2015); p. 727 – 732; Zh. Org. Khim.; vol. 51; 5; (2015); p. 727 – 732,6;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Electric Literature of 1953-99-7, A common heterocyclic compound, 1953-99-7, name is 3,4,5,6-Tetrachlorobenzene-1,2-dicarbonitrile, molecular formula is C8Cl4N2, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

Synthesis Example 6: Synthesis of 3,4,6-trichloro-5-(2-bromo-phenoxy)-phthalonitrile 5 g of 3,4,5,6-tetrachlorophthalonitrile, 3.25 g of 2-bromophenol, 3.9 g of K2CO3, and 25 ml of N,N-dimethyl formamide were put in a 100 ml flask, and then stirred while heated at 70¡ã C. When the reaction was complete, EA (ethyl acetate) was used for an extraction. After the extraction, the resultant was concentrated to obtain a solid. Herein, the obtained solid was dissolved in an small amount of dichloromethane, several times washed with hexane, filtered, and vacuum-dried to obtain 3,4,6-trichloro-5-(2-bromo-phenoxy)-phthalonitrile.

The synthetic route of 1953-99-7 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; SAMSUNG SDI CO., LTD.; JEONG, Euisoo; SEO, Hyewon; SHIN, Myoungyoup; SHIN, Sunwoong; JUNG, Juho; HAN, Gyuseok; (25 pag.)US2018/335547; (2018); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Synthetic Route of 1953-99-7, The chemical industry reduces the impact on the environment during synthesis 1953-99-7, name is 3,4,5,6-Tetrachlorobenzene-1,2-dicarbonitrile, I believe this compound will play a more active role in future production and life.

To a 100 mL flask was added the solid (4- (biphenyl-2-ylamino) -3,5,6-trichlorophthalonitrile) (1.0 g), 3,4,5,6-tetrachlorophthalonitrile (2.0 g), 1,8-Diazabicycloundec- -ene (3.0 g), and 1-pentanol (30 mL), and dissolve by heating. Then, zinc acetate (0.46 g) is added and refluxed with heating. After completion of the reaction, the solvent was removed, and the residue was purified by column chromatography. Dichloromethane was appropriately added to the obtained solid to dissolve the solid, and hexane was added to crystallize. At this time, the obtained solid was filtered and dried under vacuum to obtain a compound represented by the following general formula (7).

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 3,4,5,6-Tetrachlorobenzene-1,2-dicarbonitrile, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; Cheil Industries Co., Ltd.; Choe, Say Young; Kwon, JaeYoung; Park, Uhn B; Lee, Jong Son; Lee, Chang Ryul; Jong, Ju Ho; Choe, Mi Jin; Choe, Sung Gip; Hyung, Gyung Hee; (28 pag.)KR2015/130131; (2015); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 1953-99-7, name is 3,4,5,6-Tetrachlorobenzene-1,2-dicarbonitrile, A new synthetic method of this compound is introduced below., Recommanded Product: 3,4,5,6-Tetrachlorobenzene-1,2-dicarbonitrile

To a 100 mL flask2,4-Bis (alpha,alpha-dimethylbenzyl) -2-yloxy) -3,5,6-trichloro-phthalonitrile (1 g), 3,4,6-Trichloro-5-pentoxy-phthalonitrile (0.7 g),1,8-Diazabicycloundec-7-ene (0.8 g), 1-pentanol (7 g) and zinc acetate (0.3 g) were added and stirred while heating to 140 ¡ã C. After completion of the reaction, the mixture is concentrated and purified by column chromatography. The liquid obtained after purification is concentrated to obtain a solid. The crystallized solid is vacuum-dried to obtain a compound represented by the following general formula (9).

The synthetic route of 1953-99-7 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Samsung SDI Co., Ltd; Jeong Ui-su; Seo Hye-won; Shin Myeong-yeop; Han Gyu-seok; (40 pag.)KR2019/13136; (2019); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Related Products of 1953-99-7, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 1953-99-7 name is 3,4,5,6-Tetrachlorobenzene-1,2-dicarbonitrile, This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.

In a 100 ml flask, 3,4,5,6-tetrachlorophthalonitrile (5 g), 2-butylphenol (4.75 g), K2CO3 (3.9 g) N,N-dimethylformamide (25 ml) was added and stirred while heating to 70 ¡ã C. After completion of the reaction, the reaction mixture is extracted with EA (ethyl acetate). After extraction and concentration, a solid can be obtained. The solid thus obtained is dissolved in a small amount of dichloromethane, washed with hexane several times, filtered and vacuum dried to obtain 3,4,6-trichloro-5-(2-butyl-phenoxy)-phthalonitrile.

At the same time, in my other blogs, there are other synthetic methods of this type of compound, 3,4,5,6-Tetrachlorobenzene-1,2-dicarbonitrile, and friends who are interested can also refer to it.

Reference:
Patent; Samsung SDI Co., Ltd; Seo Hye-won; Shin Myeong-yeop; Jeong Ui-su; Han Gyu-seok; (56 pag.)KR2019/11995; (2019); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts