Category: 194808-59-8

Nitrile reduction in the presence of Boc-protected amino groups by catalytic hydrogenation over palladium-activated Raney-nickel was written by Klenke, Burkhard;Gilbert, Ian H.. And the article was included in Journal of Organic Chemistry in 2001.Electric Literature of C20H34N4O4 The following contents are mentioned in the article:

Nitriles NCCH₂CH₂NX-R-NXCH₂CH₂CN [R = (CH₂)_n, 1,2-cyclohexyl, 1,4-cyclohexyl, CHMeCH₂, X = Boc, n = 4, 7, 9, 12; R = 1,2-Ph, 1,3-Ph, 1,4-Ph, X = H] are reduced to primary amines in the presence of N-tert-butoxycarbonyl (Boc) groups. E.g., NCCH₂CH₂N(Boc)(CH₂)₄N(Boc)CH₂CH₂CN in absolute ethanol and THF was stirred with a mixture of Pd/C and Raney nickel and sodium hydroxide; the mixture was shaken for 8 h under 45 psi of hydrogen and worked up to give H₂N(CH₂)₃N(Boc)(CH₂)₄N(Boc)(CH₂)₃NH₂ in 84% yield. The reduction can be carried out under atm. H₂ pressure using com. avail. catalysts. Both Boc groups and aromatic moieties present in the starting material are well tolerated under the mild optimized conditions. This study involved multiple reactions and reactants, such as Di-tert-butyl butane-1,4-diylbis((2-cyanoethyl)carbamatE) (cas: 194808-59-8Electric Literature of C20H34N4O4).

Di-tert-butyl butane-1,4-diylbis((2-cyanoethyl)carbamatE) (cas: 194808-59-8) belongs to nitriles. Nitriles are polar, as indicated by high dipole moments. As liquids, they have high relative permittivities, often in the 30s. Nitriles are susceptible to hydrogenation over diverse metal catalysts. The reaction can afford either the primary amine (RCH2NH2) or the tertiary amine ((RCH2)3N), depending on conditions.Electric Literature of C20H34N4O4

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Polyamine functionalized carbon nanotubes: synthesis, characterization, cytotoxicity and siRNA binding was written by Singh, Prabhpreet;Samori, Cristian;Toma, Francesca Maria;Bussy, Cyrill;Nunes, Antonio;Al-Jamal, Khuloud T.;Menard-Moyon, Cecilia;Prato, Maurizio;Kostarelos, Kostas;Bianco, Alberto. And the article was included in Journal of Materials Chemistry in 2011.Computed Properties of C20H34N4O4 The following contents are mentioned in the article:

In this work the authors have synthesized a new series of cationic carbon nanotubes (CNTs) for siRNA binding. Both single- and multi-walled CNTs have been modified by addition or amidation reaction with short linear polyamine chains including putrescine, spermidine and spermine. All the new conjugates have been characterized with several spectroscopic and microscopic techniques. Their cytotoxic effects have been assessed on human lung carcinoma cell line. Finally, the authors have analyzed their capacity to bind siRNA towards the development of new carriers for gene silencing applications. The dispersibility properties and the capacity to complex siRNA of the different conjugates were strongly dependent on the position of the functional groups on CNTs (i.e. mainly at the tips following the amidation reaction or on the sidewalls by direct C-C addition). This study involved multiple reactions and reactants, such as Di-tert-butyl butane-1,4-diylbis((2-cyanoethyl)carbamatE) (cas: 194808-59-8Computed Properties of C20H34N4O4).

Di-tert-butyl butane-1,4-diylbis((2-cyanoethyl)carbamatE) (cas: 194808-59-8) belongs to nitriles. There has been no report on the microbial biosynthesis of nitriles and the physiological function of such enzymes, nor was it not even known whether aliphatic and aromatic nitriles are biological compounds or just petrochemicals. Nitriles are susceptible to hydrogenation over diverse metal catalysts. The reaction can afford either the primary amine (RCH2NH2) or the tertiary amine ((RCH2)3N), depending on conditions.Computed Properties of C20H34N4O4

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts