Category: 17626-40-3

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 17626-40-3, name is 3,4-Diaminobenzonitrile, A new synthetic method of this compound is introduced below., 17626-40-3

A generic experiment was as follows. In a two-neck roundbottomflask of 10 mL, 1,2-phenylenediamine (1a, 0.5 mmol),1,2-propyleneglycol (2a, 0.6 mmol), 1.5 mL of diethylene glycol dimethylether (diglyme), and an amount of catalyst were added.Subsequently, the reaction mixture was heated at 140 C in a siliconebath that contains a magnetic stirrer and a temperature controller.

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.

Reference:
Article; Climent; Corma; Hernandez; Hungria; Iborra; Martinez-Silvestre; Journal of Catalysis; vol. 292; (2012); p. 118 – 129;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

17626-40-3,Some common heterocyclic compound, 17626-40-3, name is 3,4-Diaminobenzonitrile, molecular formula is C7H7N3, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

Into a 100-mL round-bottom flask, was placed a solution of l,2-bis(4- methoxyphenyl)ethane-l,2-dione (200 mg, 0.74 mmol, 1.00 equiv) in acetic acid (20 mL), 3,4-diaminobenzonitrile (118.2 mg, 0.89 mmol, 1.20 equiv). The resulting solution was stirred for 1 h at reflux in an oil bath. The reaction was then quenched by the addition of water. The solids were collected by filtration and washed with MeOH. This resulted in 205 mg (71%) of 2,3-bis(4-methoxyphenyl)quinoxaline-6- carbonitrile as a yellow solid.LC-MS-PH: (ES, m/z): 368 [M+H]+

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 17626-40-3, its application will become more common.

Reference:
Patent; BIOENERGENIX; MCCALL, John, M.; MCKEARN, John; ROMERO, Donnal, L.; CLAIR, Michael; WO2011/28947; (2011); A2;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

A common compound: 17626-40-3, name is 3,4-Diaminobenzonitrile, belongs to nitriles-buliding-blocks compound, it can change the direction of chemical reaction, and react with certain compounds to generate new functional products. A new synthetic method of this compound is introduced below. 17626-40-3

5.0 g (37.56 mmol) of 3,4-diaminobenzonitrile was dissolved in 20 ml of trifluoroacetic acid, the reaction was refluxed under nitrogen atmosphere for 10 hours, then sinking into water, the filtrate was collected by filtration, washed three times with water, and dried to give 4.91 g (62.0% yield)

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 17626-40-3, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; Chen Yaoteng; Huang Bingzhao; Zheng Zhilong; Chen Siyuan; Wei Anxing; (19 pag.)CN103896849; (2017); B;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts