Liu, Renshuai’s team published research in Bioorganic Chemistry in 2019 | CAS: 17201-43-3

4-Cyanobenzyl bromide(cas: 17201-43-3) is an important intermediate for pharmaceutical production. It can be used for the synthesis of a series of piperidine-linked aromatic diimidazolines, which have been synthesized as conformationally restricted congeners of the anti-Pneumocystis carinii (PCP) drug, Pentamidine.Computed Properties of C8H6BrN

The author of 《Discovery and development of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid derivatives as Bcl-2/Mcl-1 inhibitors》 were Liu, Renshuai; Liu, Lulu; Yang, Xinying; Fang, Hao. And the article was published in Bioorganic Chemistry in 2019. Computed Properties of C8H6BrN The author mentioned the following in the article:

Bcl-2 family proteins play a vital role for cancer cell in escaping apoptosis, and small-mol. anti-apoptotic Bcl-2 protein inhibitors have been developed as new anticancer therapies. In current study, a series of substituted 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid derivatives were developed based on the lead compound 1 (Ki = 5.2 μM against Bcl-2 protein). The fluorescence polarization assays suggested that active compounds possessed potent binding affinities to both Bcl-2 and Mcl-1 protein, but had minor or no binding affinities to Bcl-XL protein. MTT assays showed that these compounds had certain anti-proliferative activities against cancer cells. Furthermore, it was found that active compound 11t(I) could induce cell apoptosis and caspase-3 activation in a dose-dependent manner in Jurkat cells. In addition to this study using 4-Cyanobenzyl bromide, there are many other studies that have used 4-Cyanobenzyl bromide(cas: 17201-43-3Computed Properties of C8H6BrN) was used in this study.

4-Cyanobenzyl bromide(cas: 17201-43-3) is an important intermediate for pharmaceutical production. It can be used for the synthesis of a series of piperidine-linked aromatic diimidazolines, which have been synthesized as conformationally restricted congeners of the anti-Pneumocystis carinii (PCP) drug, Pentamidine.Computed Properties of C8H6BrN

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Akunuri, Ravikumar’s team published research in ChemistrySelect in 2022 | CAS: 17201-43-3

4-Cyanobenzyl bromide(cas: 17201-43-3) is a white solid. Its melting point is 113-117°C, and flash point is 125.1°C. It is insoluble in water at 20°C. It is stable under normal temperatures and pressures. It should be stored at 0-5°C.COA of Formula: C8H6BrN

In 2022,Akunuri, Ravikumar; Vadakattu, Manasa; Kaul, Grace; Akhir, Abdul; Saxena, Deepanshi; Ahmad, Mohammad Naiyaz; Bujji, Sushmitha; Joshi, Swanand Vinayak; Dasgupta, Arunava; Yaddanapudi, Venkata Madhavi; Chopra, Sidharth; Nanduri, Srinivas published an article in ChemistrySelect. The title of the article was 《Synthesis and Antibacterial Evaluation of 3,4-Dihydro-1H-benzo[b]azepine-2,5-dione Derivatives》.COA of Formula: C8H6BrN The author mentioned the following in the article:

Fused-azepinones are interesting heterocyclic scaffolds present in various natural products and synthetic derivatives with potent kinase inhibition, anti-cancer, anti-inflammatory, anti-HIV, neuroprotective, anti-fouling and other biol. activities. These fused-azepinones are also known for their antimicrobial activity against the Plasmodium falciparum, Leishmania, Escherichia coli, and Streptococcus pneumonia. In the present work, author synthesized a library of 3,4-dihydro-1H-benzo[b]azepine-2,5-dione derivatives and evaluated them for their antibacterial potential against a panel of bacterial pathogens. The Structure-activity relationship studies revealed the essential structural features for the promising antibacterial properties against Staphylococcus aureus and Mycobacterium tuberculosis with MIC 4-64μg/mL. In addition, these compounds exhibited favorable selectivity index (SI≥10) in cytotoxicity studies. With the interesting antibacterial properties exhibited and good selectivity index, these compounds have emerged as promising candidates for further development. In the experiment, the researchers used many compounds, for example, 4-Cyanobenzyl bromide(cas: 17201-43-3COA of Formula: C8H6BrN)

4-Cyanobenzyl bromide(cas: 17201-43-3) is a white solid. Its melting point is 113-117°C, and flash point is 125.1°C. It is insoluble in water at 20°C. It is stable under normal temperatures and pressures. It should be stored at 0-5°C.COA of Formula: C8H6BrN

Referemce:
Nitrile – Wikipedia,
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Guo, Ruotao’s team published research in Journal of Luminescence in 2020 | CAS: 17201-43-3

4-Cyanobenzyl bromide(cas: 17201-43-3) is used in the synthesis of ligands containing a chelating pyrazolyl-pyridine group with a pendant aromatic nitrile. It is also useful in the preparation of 4-[(2H-tetra-zol-2-yl)methyl]benzonitrile by reaction with 2H-tetrazole in the presence of potassium hydroxide.Electric Literature of C8H6BrN

《Fluorinated/non-fluorinated bisphenoxy benzyl ether zinc(II) phthalocyanine: Synthesis, photoinduced intramolecular electron transfer and intermolecular energy transfer》 was published in Journal of Luminescence in 2020. These research results belong to Guo, Ruotao; Chen, Kuizhi; Yu, Zhiqiang; Ye, Qiuhao; Xiao, Wenling; Huang, Bingcheng; Guan, Xinqiao; Peng, Yiru. Electric Literature of C8H6BrN The article mentions the following:

Two novel series of fluorinated and non-fluorinated bisphenoxy benzyl ether with cyano/pentyl terminal groups zinc(II) phthalocyanines were synthesized. Their structures were characterized by elemental anal., IR, 1H NMR, 13C NMR, ESI-MS and MALDI-TOF-MS methods. The photophys. properties, photoinduced intramol. electron transfer, and photoinduced intramol. energy transfer of fluorinated and non-fluorinated phthalocyanines were compared by UV-Vis and fluorescence spectroscopic methods. These properties exhibited fluorinated substituents and terminal groups nature dependence. Fluorinated zinc(II) phthalocyanine with pentyl ester terminal groups had the highest molar absorption coefficient, fluorescence intensity and fluorescence lifetime. Non-fluorinated zinc(II) phthalocyanine with cyano terminal groups exhibited the highest energy transfer efficiency. In addition to this study using 4-Cyanobenzyl bromide, there are many other studies that have used 4-Cyanobenzyl bromide(cas: 17201-43-3Electric Literature of C8H6BrN) was used in this study.

4-Cyanobenzyl bromide(cas: 17201-43-3) is used in the synthesis of ligands containing a chelating pyrazolyl-pyridine group with a pendant aromatic nitrile. It is also useful in the preparation of 4-[(2H-tetra-zol-2-yl)methyl]benzonitrile by reaction with 2H-tetrazole in the presence of potassium hydroxide.Electric Literature of C8H6BrN

Referemce:
Nitrile – Wikipedia,
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Klunda, Tomas’s team published research in Bioorganic Chemistry in 2019 | CAS: 17201-43-3

4-Cyanobenzyl bromide(cas: 17201-43-3) can reacts with 2H-tetrazole in the presence of KOH to yield 4-[(2H-tetra-zol-2-yl)methyl]benzonitrile. And it may be used in the synthesis of ligands containing a chelating pyrazolyl-pyridine group with a pendant aromatic nitrile.COA of Formula: C8H6BrN

COA of Formula: C8H6BrNIn 2019 ,《Synthesis of N-benzyl substituted 1,4-imino-L-lyxitols with a basic functional group as selective inhibitors of Golgi α-mannosidase IIb》 appeared in Bioorganic Chemistry. The author of the article were Klunda, Tomas; Sestak, Sergej; Kona, Juraj; Polakova, Monika. The article conveys some information:

Inhibition of the biosynthesis of complex N-glycans in the Golgi apparatus is one of alternative ways to suppress growth of tumor tissue. Eight N-benzyl substituted 1,4-imino-L-lyxitols with basic functional groups (amine, amidine, guanidine), hydroxyl and fluoro groups were prepared, optimized their syntheses and tested for their ability to inhibit several α-mannosides from the GH family 38 (GMIIb, LManII and JBMan) as models for human Golgi and lysosomal α-mannoside II. All compounds were found to be selective inhibitors of GMIIb. The most potent structure bearing guanidine group, inhibited GMIIb at the micromolar level (Ki = 19 ± 2 μM) while no significant inhibition (>2 mM) of LManII and JBMan was observed Based on mol. docking and pKa calculations this structure may form two salt bridges with aspartate dyad of the target enzyme improving its inhibitory potency compared with other N-benzyl substituted derivatives published in this and previous studies. The results came from multiple reactions, including the reaction of 4-Cyanobenzyl bromide(cas: 17201-43-3COA of Formula: C8H6BrN)

4-Cyanobenzyl bromide(cas: 17201-43-3) can reacts with 2H-tetrazole in the presence of KOH to yield 4-[(2H-tetra-zol-2-yl)methyl]benzonitrile. And it may be used in the synthesis of ligands containing a chelating pyrazolyl-pyridine group with a pendant aromatic nitrile.COA of Formula: C8H6BrN

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Yatam, Satyanarayana’s team published research in ChemistrySelect in 2019 | CAS: 17201-43-3

4-Cyanobenzyl bromide(cas: 17201-43-3) is an important intermediate for pharmaceutical production. It can be used for the synthesis of a series of piperidine-linked aromatic diimidazolines, which have been synthesized as conformationally restricted congeners of the anti-Pneumocystis carinii (PCP) drug, Pentamidine.Recommanded Product: 4-Cyanobenzyl bromide

The author of 《2-Mercapto Benzthiazole Coupled Benzyl Triazoles as New COX-2 Inhibitors: Design, Synthesis, Biological Testing and Molecular Modeling Studies》 were Yatam, Satyanarayana; Jadav, Surender Singh; Gundla, Krishna Prasadh; Paidikondala, Kalyani; Ankireddy, Ashok Reddy; Babu, Bathini Nagendra; Ahsan, Mohamed Jawed; Gundla, Rambabu. And the article was published in ChemistrySelect in 2019. Recommanded Product: 4-Cyanobenzyl bromide The author mentioned the following in the article:

A series of 2-mercapto benzothiazole linked with triazoles I (R = 4-tert-butylphenyl, naphthalen-2-yl, 3,4-dichlorolphenyl, etc.) was designed based on our previous exptl. evaluation of benzothiazole allied oxadiazoles and synthesized in two step starting from the 2-mercaptan precursor. The insilico binding mode interpretations in both COX-1/COX-2 was investigated, and their probable binding energies were predicted and ADMET properties were calculated The mol. level interactions of the designed library indicated, the aryl ring united with triazole was occupying as mefenamic acid in COX-2 active site. All the benzothiazoles were evaluated for their COX inhibitory activities as per the standard protocol reported elsewhere. The compounds I (R = 2-chlorophenyl (A), 4-carboxyphenyl and 4-carbamoylphenyl) based benzothiazoles showed the most significant COX-2 inhibitory activity with an IC50 of 4.1, 4.3 and 5.4 μM resp. The time dependant increase in inhibition of inflammation of above COX-2 inhibitors in invivo anti-inflammatory evaluation was noticed. Addnl., I (R = 3-fluorophenyl) expressed the significant DPPH scavenging activity with 80.45 percent inhibition at 100 μM and an IC50 of 27.8 μM. Furthermore, the 50 ns mol. dynamic simulations of (A) to interpret the constant residue interactions that might liable for the COX selectivity were presented. Later, they also have been tested for cancer lines at NCI and the obtained data were provided. In the part of experimental materials, we found many familiar compounds, such as 4-Cyanobenzyl bromide(cas: 17201-43-3Recommanded Product: 4-Cyanobenzyl bromide)

4-Cyanobenzyl bromide(cas: 17201-43-3) is an important intermediate for pharmaceutical production. It can be used for the synthesis of a series of piperidine-linked aromatic diimidazolines, which have been synthesized as conformationally restricted congeners of the anti-Pneumocystis carinii (PCP) drug, Pentamidine.Recommanded Product: 4-Cyanobenzyl bromide

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Zeng, Qing-Xuan’s team published research in Bioorganic Chemistry in 2021 | CAS: 17201-43-3

4-Cyanobenzyl bromide(cas: 17201-43-3) is used in the synthesis of ligands containing a chelating pyrazolyl-pyridine group with a pendant aromatic nitrile. It is also useful in the preparation of 4-[(2H-tetra-zol-2-yl)methyl]benzonitrile by reaction with 2H-tetrazole in the presence of potassium hydroxide.Reference of 4-Cyanobenzyl bromide

Zeng, Qing-Xuan; Wang, Kun; Zhang, Xin; Shi, Yu-Long; Dou, Yue-Ying; Guo, Zhi-Hao; Zhang, Xin-Tong; Zhang, Na; Deng, Hong-Bin; Li, Ying-Hong; Song, Dan-Qing published their research in Bioorganic Chemistry in 2021. The article was titled 《Structure-activity relationship and biological evaluation of 12 N-substituted aloperine derivatives as PD-L1 down-regulatory agents through proteasome pathway》.Reference of 4-Cyanobenzyl bromide The article contains the following contents:

Twenty-nine 12 N-substituted aloperine derivatives were synthesized and screened for suppression on PD-L1 expression in H460 cells, as a continuation of our work. Systematic structural modifications led to the identification of compound I as the most active PD-L1 modulator. Compound I could significantly down-regulate both constitutive and inductive PD-L1 expression in NSCLC cells, and successively enhance the cytotoxicity of co-cultured T cells against tumor cells at the concentration of 20μM. Also, it exhibited a moderate in vivo anticancer efficacy against Lewis tumor xenograft with a stable PK and safety profile. The mechanism study indicated that I mediated the degradation of PD-L1 through a proteasome pathway, rather than a lysosome route. These results provided the powerful information for cancer immunotherapy of aloperine derivatives with unique endocyclic skeleton by targeting PD-L1 to activate immune cells to kill cancer cells. The experimental part of the paper was very detailed, including the reaction process of 4-Cyanobenzyl bromide(cas: 17201-43-3Reference of 4-Cyanobenzyl bromide)

4-Cyanobenzyl bromide(cas: 17201-43-3) is used in the synthesis of ligands containing a chelating pyrazolyl-pyridine group with a pendant aromatic nitrile. It is also useful in the preparation of 4-[(2H-tetra-zol-2-yl)methyl]benzonitrile by reaction with 2H-tetrazole in the presence of potassium hydroxide.Reference of 4-Cyanobenzyl bromide

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Shi, Jianyi’s team published research in Chinese Chemical Letters in 2022 | CAS: 17201-43-3

4-Cyanobenzyl bromide(cas: 17201-43-3) is an important intermediate for pharmaceutical production. It can be used for the synthesis of a series of piperidine-linked aromatic diimidazolines, which have been synthesized as conformationally restricted congeners of the anti-Pneumocystis carinii (PCP) drug, Pentamidine.Application In Synthesis of 4-Cyanobenzyl bromide

In 2022,Shi, Jianyi; Zeng, Zheng; Xu, Shengting; Cai, Zechun; Luo, Yuehua; Fan, Yongbo; Zhu, Zhongzhi; Wen, Tingting; Chen, Xiuwen published an article in Chinese Chemical Letters. The title of the article was 《Cross-coupling of 2-methylquinolines and in-situ activated isoquinolines: Construction of 1,2-disubstituted isoquinolinones》.Application In Synthesis of 4-Cyanobenzyl bromide The author mentioned the following in the article:

In this study, a method was developed to form C(sp3)-C(sp2) bonds via copper catalyst-promoted cross coupling of 2-methylquinolines I (R1 = H, 6-Me, 7-Cl, etc.) and in-situ-activated 3-haloisoquinolines II (R2 = H, 5-Br, 4-Br; X = Br, Cl) under mild conditions. The multi-component tandem reaction was used to construct new C-N, C=O and C-C bonds in one pot via sequential functionalization of the N1, C3 and C1 positions of 3-haloisoquinolines. This method can be used to efficiently access 1,2-disubstituted isoquinolinones III (R4 = H, 6-Br, 7-Br) by the three-component reaction of 3-halogen isoquinolines, alkyl halides R3CH2Y (R3 = Ph, 2,4-difluorophenyl, 2-naphthyl, etc.; Y = Br, Cl), and 2-methylquinolines. In the part of experimental materials, we found many familiar compounds, such as 4-Cyanobenzyl bromide(cas: 17201-43-3Application In Synthesis of 4-Cyanobenzyl bromide)

4-Cyanobenzyl bromide(cas: 17201-43-3) is an important intermediate for pharmaceutical production. It can be used for the synthesis of a series of piperidine-linked aromatic diimidazolines, which have been synthesized as conformationally restricted congeners of the anti-Pneumocystis carinii (PCP) drug, Pentamidine.Application In Synthesis of 4-Cyanobenzyl bromide

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Nambo, Masakazu’s team published research in Nature Communications in 2019 | CAS: 17201-43-3

4-Cyanobenzyl bromide(cas: 17201-43-3) is used in the synthesis of ligands containing a chelating pyrazolyl-pyridine group with a pendant aromatic nitrile. It is also useful in the preparation of 4-[(2H-tetra-zol-2-yl)methyl]benzonitrile by reaction with 2H-tetrazole in the presence of potassium hydroxide.Related Products of 17201-43-3

In 2019,Nature Communications included an article by Nambo, Masakazu; Yim, Jacky C.-H.; Freitas, Luiza B. O.; Tahara, Yasuyo; Ariki, Zachary T.; Maekawa, Yuuki; Yokogawa, Daisuke; Crudden, Cathleen M.. Related Products of 17201-43-3. The article was titled 《Modular synthesis of α-fluorinated arylmethanes via desulfonylative cross-coupling》. The information in the text is summarized as follows:

Herein, Pd-catalyzed Suzuki-Miyaura cross-coupling of α-fluorinated benzylic triflones with arylboronic acids affording structurally diverse α-fluorinated diarylmethanes Ar1C(X)(F)Ar2 [Ar1 = 4-t-BuC6H4, 4-O2NC6H4, 4-CO2MeC6H4, etc.; Ar2 = Ph, 2-MeC6H4, 1-naphthyl, etc.] was reported. The ease of synthesis of fluorinated triflones as the key starting materials enabled powerful late-stage transformations of known biol. active compounds into fluorinated analogs. The experimental part of the paper was very detailed, including the reaction process of 4-Cyanobenzyl bromide(cas: 17201-43-3Related Products of 17201-43-3)

4-Cyanobenzyl bromide(cas: 17201-43-3) is used in the synthesis of ligands containing a chelating pyrazolyl-pyridine group with a pendant aromatic nitrile. It is also useful in the preparation of 4-[(2H-tetra-zol-2-yl)methyl]benzonitrile by reaction with 2H-tetrazole in the presence of potassium hydroxide.Related Products of 17201-43-3

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Reddyrajula, Rajkumar’s team published research in ChemistrySelect in 2019 | CAS: 17201-43-3

4-Cyanobenzyl bromide(cas: 17201-43-3) can reacts with 2H-tetrazole in the presence of KOH to yield 4-[(2H-tetra-zol-2-yl)methyl]benzonitrile. And it may be used in the synthesis of ligands containing a chelating pyrazolyl-pyridine group with a pendant aromatic nitrile.Recommanded Product: 17201-43-3

Recommanded Product: 17201-43-3In 2019 ,《Quinoline-1,2,3-triazole Hybrids: Design and Synthesis through Click Reaction, Evaluation of Anti-Tubercular Activity, Molecular Docking and In Silico ADME Studies》 appeared in ChemistrySelect. The author of the article were Reddyrajula, Rajkumar; Dalimba, Udayakumar. The article conveys some information:

A new series of quinoline-1,2,3-triazole derivatives I (R = benzyl, phenacyl, 4-methoxy phenacyl, etc.), II were designed based on the mol. hybridization concept and the mols. were synthesized by employing a click chem. approach. The pharmacophoric units (quinoline and 1,2,3-triazole) are linked through either an ether or an amide functionality; such a simple structural modification of the linker group significantly enhanced the anti-tubercular activity of the mols. and all the amide derivatives showed better inhibition activity as compared to their ether analogs. However, these compounds did not inhibit significantly the growth of tested bacterial strains: the activity profile is similar to that observed for standard anti-TB drugs indicating the specificity of these compounds towards the M.tuberculosis strain. The mol. docking studies of the active compounds with two target enzymes (Inh A and CYP121) of M.tuberculosis revealed the strong binding interactions, mainly through hydrogen bonding, between the mols. and the target receptors. Furthermore, prediction of in silico-ADME (A: absorption, D: distribution, M: metabolism and E: excretion) parameters indicated that these compounds have an excellent oral bioavailability. The results suggest that these quinoline-1,2,3-triazole hybrids are a promising class of mol. entities for the development of new anti-tubercular leads.4-Cyanobenzyl bromide(cas: 17201-43-3Recommanded Product: 17201-43-3) was used in this study.

4-Cyanobenzyl bromide(cas: 17201-43-3) can reacts with 2H-tetrazole in the presence of KOH to yield 4-[(2H-tetra-zol-2-yl)methyl]benzonitrile. And it may be used in the synthesis of ligands containing a chelating pyrazolyl-pyridine group with a pendant aromatic nitrile.Recommanded Product: 17201-43-3

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Eldehna, Wagdy M.’s team published research in Bioorganic Chemistry in 2021 | CAS: 17201-43-3

4-Cyanobenzyl bromide(cas: 17201-43-3) is an important intermediate for pharmaceutical production. It can be used for the synthesis of a series of piperidine-linked aromatic diimidazolines, which have been synthesized as conformationally restricted congeners of the anti-Pneumocystis carinii (PCP) drug, Pentamidine.HPLC of Formula: 17201-43-3

Eldehna, Wagdy M.; El Hassab, Mahmoud A.; Abo-Ashour, Mahmoud F.; Al-Warhi, Tarfah; Elaasser, Mahmoud M.; Safwat, Nesreen A.; Suliman, Howayda; Ahmed, Marwa F.; Al-Rashood, Sara T.; Abdel-Aziz, Hatem A.; El-Haggar, Radwan published an article in 2021. The article was titled 《Development of isatin-thiazolo[3,2-a]benzimidazole hybrids as novel CDK2 inhibitors with potent in vitro apoptotic anti-proliferative activity: Synthesis, biological and molecular dynamics investigations》, and you may find the article in Bioorganic Chemistry.HPLC of Formula: 17201-43-3 The information in the text is summarized as follows:

The present work aims at developing a new set of small mols. featuring the privileged isatin scaffold conjugated with a thiazolo[3,2-a]benzimidazole (TBI) motif through a cleavable hydrazide linker I (R = H, F, Br, OMe and NO2) and II (R = H, Br; R1 = Me, allyl, Bn, etc.) as potential anticancer CDK2 inhibitors. The growth of the two examined cell lines was significantly inhibited by most the prepared hybrids with IC50 ranges; (2.60 +/- 1.47-20.90 +/- 1.17μM, against MDA-MB-231) and (1.27 +/- 0.06-16.83 +/- 0.95μM, against MCF-7). They exerted a significance alteration in the cell cycle progression, in addition to an apoptosis induction within both MDA-MB-231 and MCF-7 cells. Furthermore, I (R = H), I (R = OMe) and II (R = H; R1 = Me) displayed potent CDK2 inhibitory action (IC50 = 96.46 +/- 5.3, 26.24 +/- 1.4 and 42.95 +/- 2.3 nM, resp.). Interestingly, the most potent CDK2 inhibitor I (R = OMe) achieved the best binding score (-11.2 Kcal/mol) and formed the most stable complex with CDK2 enzyme (RMSD = 1.24 Å ) in a 100 ns MD simulation. In addition, the MM-PBSA calculations ascribed the lowest binding free energy to the I (R = OMe)-CDK2 complex (-323.69 +/- 15.17 kJ/mol). Finally, these results suggested hybrid I (R = OMe) as a good candidate for further optimization as promising breast cancer antitumor agent and CDK2 inhibitor. The experimental process involved the reaction of 4-Cyanobenzyl bromide(cas: 17201-43-3HPLC of Formula: 17201-43-3)

4-Cyanobenzyl bromide(cas: 17201-43-3) is an important intermediate for pharmaceutical production. It can be used for the synthesis of a series of piperidine-linked aromatic diimidazolines, which have been synthesized as conformationally restricted congeners of the anti-Pneumocystis carinii (PCP) drug, Pentamidine.HPLC of Formula: 17201-43-3

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts