Category: 170230-87-2

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 170230-87-2, name is 4-Amino-3-ethylbenzonitrile, This compound has unique chemical properties. The synthetic route is as follows., Recommanded Product: 170230-87-2

Description 25; 4-bromo-3-ethylbenzonitrile (D25); A mixture of 4-amino-3-ethylbenzonitrile (3.00 g, 20.5 mmol) and copper (II) bromide (6.88 g, 30.8 mmol) in acetonitrile (115 ml.) was stirred under argon before addition of isoamylnitrite (3.60 g, 30.8 mmol) dropwise through a condenser and the mixture was heated to 60 0C for 2.5 h. The mixture was stood at room temperature overnight under argon before it was concentrated. Diethyl ether was added and the mixture washed with saturated aqueous ammonium chloride followed by 2M sodium hydroxide. The aqueous was extracted with further diethyl ether before the combined organic fractions were dried (phase separator) and evaporated. Purification of the material in three batches was by reverse phase chromatography, eluting 5-100 % acetonitrile in water to give the title compound 787 mg, 3.74 mmol). deltaH (MeOD, 400 MHz): 7.74 (1 H, d), 7.67 (1 H, d), 7.45 (1 H, dd), 2.82 (2H, q), 1.24 (3H, t) ppm

According to the analysis of related databases, 170230-87-2, the application of this compound in the production field has become more and more popular.

Reference:
Patent; GLAXO GROUP LIMITED; WO2008/74820; (2008); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts