Category: 1129-35-7

Adding a certain compound to certain chemical reactions, such as: 1129-35-7, name is Methyl 4-cyanobenzoate, belongs to nitriles-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 1129-35-7, SDS of cas: 1129-35-7

To a stirred solution of methyl 4-cyanobenzoate (0.9 g, 5.6 mmol) in methanol (12 mL), sodium bicarbonate (0.5 g, 6.1 mmol) and hydroxylamine hydrochloride (0.4 g, 5.6 mmol) were added. The resulting reaction mixture was heated to reflux for 4 h. After completion of the reaction, the reaction mixture was cooled to 25 oC and filtered. The filtrate was concentrated under reduced pressure to obtain methyl-4-(N’-hydroxycarbamimidoyl)benzoate (0.9 g, 4.6 mmol, 83 % yield).

At the same time, in my other blogs, there are other synthetic methods of this type of compound, Methyl 4-cyanobenzoate, and friends who are interested can also refer to it.

Reference:
Patent; PI INDUSTRIES LTD.; BHUJADE, Paras Raybhan; PAWAR, Rajesh; NAIK, Maruti N; POTLAPALLY, Rajender Kumar; TEMBHARE, Nitin Ramesh; AUTKAR, Santosh Shridhar; GARG, Ruchi; VENKATESHA, Hagalavadi M; KLAUSENER, Alexander G.M.; RAMAKRISHNA, Visannagari; ADHAV, Nilesh Bharat; TRIVEDI, Pooja; (138 pag.)WO2019/150219; (2019); A2;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Related Products of 1129-35-7, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 1129-35-7, name is Methyl 4-cyanobenzoate, This compound has unique chemical properties. The synthetic route is as follows.

General procedure: Hydrazine hydrate 64% (v/v) (30.0 mL, 0.33 mol) was heated up to 50-60 C. The methyl ester 3 (0.01 mol) was added and the mixture was heated at reflux for 10 min. The cooling was performed sequentially in water bath, followed by ice bath and dry ice-ethanol bath. The precipitate was filtered and washed with cold water.

The chemical industry reduces the impact on the environment during synthesis Methyl 4-cyanobenzoate. I believe this compound will play a more active role in future production and life.

Electric Literature of 1129-35-7,Some common heterocyclic compound, 1129-35-7, name is Methyl 4-cyanobenzoate, molecular formula is C9H7NO2, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

A mixture OF METHYL-4-CYANOBENZOATE (5.0 g, 0. 031 MOL) and diethyl dithiophosphate (11.5 g, 0.062 mol) in water (100 mL) was stirred overnight at 80C under a nitrogen atmosphere. The reaction mixture was allowed to cool to ambient temperatures and the solid was filtered and washed with water (100 mL). The solid was then dried in vacuo at 40C to give the crude product (4.74 g, 78%).

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route Methyl 4-cyanobenzoate, its application will become more common.

Reference:
Patent; APPLIED RESEARCH SYSTEMS ARS HOLDING N.V.; WO2005/11685; (2005); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Adding a certain compound to certain chemical reactions, such as: 1129-35-7, name is Methyl 4-cyanobenzoate, belongs to nitriles-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 1129-35-7, 1129-35-7

A mixture of methyl 4- cyanobenzoate (5.0 g, 31.0 mmol) and Omicron,Omicron-diethyl hydrogen dithiophosphate (10.41 g, 62 mmol) in water (100 mL) was stirred at 80 C for 16 h under N2. The mixture was cooled to 20 C and filtered. The precipitate was washed with water (50 mL) and dried under vacuum to give crude methyl 4-(aminocarbothioyl)benzoate (5.93 g, 98%) as a yellow powder: mp (water) 181-184 C; 1H NMR delta 10.04 (br s, 1 H, NH2), 9.65 (br s, 1 H, NH2), 7.83-8.00 (m, 4 H, H-2, H-3, H-5, H-6), 3.88 (s, 3 H, OCH3); MS m/z 196.5 (MH+, 100%).

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Methyl 4-cyanobenzoate, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY; AUCKLAND UNISERVICES LIMITED; RUGA CORPORATION; GIACCA, Amato; LAI, Edwin; RAZORENOVA, Olga; CHAN, Denise; HAY, Michael, Patrick; BONNET, Muriel; SUN, Connie; TABIBIAZAR, Ray; YUEN, Po-wai; WO2013/155338; (2013); A2;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts