Category: 1019607-55-6

Wang, Qile; Zheng, Nan published their research in Organic Letters on December 20 ,2019. The article was titled 《Difunctionalization of Cyclopropyl Amines with N-Iodosuccinimide (NIS) or in Situ Formed Cyanogen Iodide (ICN)》.Application of 1019607-55-6 The article contains the following contents:

Herein, a 1,3-difunctionalization of cyclopropylamines that serve as a π nucleophile in a two-electron (2e) SN2-like ring opening pathway is described. N-Iodosuccinimide (NIS) or in situ generated cyanogen iodide (ICN) is employed as electrophilic iodinating reagents in conjunction with TMSCN or succinimide to furnish multiple pairs of functional groups disposed in a 1,3-manner. This 2e ring opening manifold overcomes the constraint of previously reported 1e protocol as demonstrated by successful activation of monocyclic tertiary cyclopropylamines. In the experiment, the researchers used many compounds, for example, 4-(Cyclopropylamino)benzonitrile(cas: 1019607-55-6Application of 1019607-55-6)

4-(Cyclopropylamino)benzonitrile(cas: 1019607-55-6) belongs to anime. Many important products require amines as part of their syntheses. Methylamine is utilized in the production of the analgesic meperidine (trade name Demerol) and the photographic developer Metol (trademark), and dimethylamine is used in the synthesis of the antihistamine diphenhydramine (trade name Benadryl), the solvent dimethylformamide (DMF), and the rocket propellant 1,1-dimethylhydrazine. The synthesis of the insect repellent N,N-diethyl-m-toluamide (DEET) incorporates diethylamine while that of the synthetic fibre Kevlar requires aromatic amines.Application of 1019607-55-6

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Zhang, Mingkai; Xu, Peilin; Vendola, Alex J.; Allais, Christophe; Dechert Schmitt, Anne-Marie; Singer, Robert A.; Morken, James P. published an article in Angewandte Chemie, International Edition. The title of the article was 《Stereocontrolled Pericyclic and Radical Cycloaddition Reactions of Readily Accessible Chiral Alkenyl Diazaborolidines》.SDS of cas: 1019607-55-6 The author mentioned the following in the article:

In this paper is described an easily synthesized chiral diazaborolidine that is inexpensive, stable, and provides excellent stereoselection across a number of reaction classes. These versatile compounds possess utility in four different classes of cycloaddition reactions, offering good yield and stereoselectivity. X-ray structure anal. provides insight about the origin of stereocontrol. In the experiment, the researchers used 4-(Cyclopropylamino)benzonitrile(cas: 1019607-55-6SDS of cas: 1019607-55-6)

4-(Cyclopropylamino)benzonitrile(cas: 1019607-55-6) belongs to anime. Amines can be classified according to the nature and number of substituents on nitrogen. Aliphatic amines contain only H and alkyl substituents. Aromatic amines have the nitrogen atom connected to an aromatic ring.Important amines include amino acids, biogenic amines, trimethylamine, and aniline. Inorganic derivatives of ammonia are also called amines, such as monochloramine (NClH2).SDS of cas: 1019607-55-6

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts