Estruch-Blasco, Manel published the artcileRadical Arylation of Triphenyl Phosphite Catalyzed by Salicylic Acid: Mechanistic Investigations and Synthetic Applications, Formula: C7H6N2, the main research area is phosphonate aryl preparation organocatalytic diazonium arylation triphenyl phosphite; aromatic amine diazotization radical coupling triphenyl phosphite preparation arylphosphonate.
A straightforward and scalable methodol. to synthesize di-Ph arylphosphonates at 20° within 1-2 h is reported using inexpensive salicylic acid as the catalytic promoter of the reaction. Reaction of aromatic amines ArNH2 with P(OPh)3 and Bu nitrite in the presence of 10 mol% of salicylic acid afforded arylphosphonates ArP(O)(OPh)2 with up to 94% yield. Mechanistic investigations suggest that the reaction proceeds via radical-radical coupling, consistent with the so-called persistent radical effect. The reaction tolerated a wide range of functional groups and heteroaromatic moieties. The synthetic usefulness and the unique reactivity of the obtained phosphonates were demonstrated in different one-step transformations.
Journal of Organic Chemistry published new progress about Aromatic amines Role: RCT (Reactant), RACT (Reactant or Reagent). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Formula: C7H6N2.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts