Chen, Chen published the artcilePalladium-Catalyzed Carbamoyl-Carbamoylation/ Carboxylation/Thioesterification of Alkene-Tethered Carbamoyl Chlorides Using Mo(CO)6 as the Carbonyl Source, Safety of 2-Aminobenzonitrile(Flakes or Chunks), the main research area is aryl oxindole preparation; alkene tethered carbamoyl chloride carbamoylation palladium catalyst.
A palladium-catalyzed carbamoyl-carbamoylation/carboxylation/thioesterification of alkene-tethered carbamoyl chlorides such as I [R1 = H, 5-Cl, 7-Me, etc.; R2 = Bn, PMB; R3 = Me, n-Bu, Ph, etc.] using Mo(CO)6 as the carbonyl source was reported. The reactions were typically performed with good functional group compatibility and tolerated different nucleophiles (amines, alcs., phenols, thiols and water), which provided amidated/esterificated/thioesterificated/carboxylated oxindoles or lactams such as II [R4 = Ph, 2-tolyl, 1-naphthyl, etc.; R5 = H, Me] bearing an all-carbon quaternary stereocenter under CO gas-free conditions. Furthermore, natural product mutation and divergent late-stage derivatization were the important practical features.
Advanced Synthesis & Catalysis published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Safety of 2-Aminobenzonitrile(Flakes or Chunks).
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts