Hendrick, Charles E. published the artcileInsertion of Arynes into N-Halo Bonds: A Direct Approach to o-Haloaminoarenes, Quality Control of 204078-32-0, the main research area is haloaminoarene regioselective preparation; insertion aryne nitrogen halo bond.
A new approach to access o-haloaminoarenes has been achieved by insertion of arynes into a nitrogen-halide bond (N-X). This transition-metal-free transformation displays a broad substrate scope of arynes, good compatibility with functional groups, and high regioselectivity. Representative transformations of the o-haloaminoarenes are described to highlight their utility for rapid access to diversely functionalized aminoarene derivatives E.g., treating morpholine with NCS, followed by addition of 2-(trimethylsilyl)phenyl triflate and CsF, gave 67% o-haloaminoarene derivative (I).
Organic Letters published new progress about Amines Role: SPN (Synthetic Preparation), PREP (Preparation) (halo). 204078-32-0 belongs to class nitriles-buliding-blocks, name is 2-Morpholinobenzonitrile, and the molecular formula is C11H12N2O, Quality Control of 204078-32-0.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts