Ram, Vishnu Ji et al. published their research in Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry in 1997 |CAS: 75629-62-8

The Article related to diheteroarylmethane preparation, methane diheteroaryl preparation, nitrile condensation cyclization, Heterocyclic Compounds (More Than One Hetero Atom): General and other aspects.SDS of cas: 75629-62-8

On May 31, 1997, Ram, Vishnu Ji; Nath, Mahendra published an article.SDS of cas: 75629-62-8 The title of the article was Synthesis of diheteroarylmethanes from activated nitriles. And the article contained the following:

Novel procedures for the preparation of diheteroarylmethanes, e.g., the pyrimidinylindolylmethanes I (R = H, benzyl; R1 = amino, Me, Ph, pyridyl, morpholino), were developed from the base-catalyzed condensation-cyclization of indolylmethylmalononitrile II (R = H, R1 = H, benzyl) with amidine, dicyandiamide, hydroxylamine, hydrazine, and thioglycolic acid. The acid catalyzed reaction of II (R2 = bond) with thiosemicarbazide affords thiadiazole III. Base-catalyzed reaction of 3-indolylacetonitrile with dicyandiamide gives sym. triazine IV. The experimental process involved the reaction of 2-((1H-Indol-3-yl)methylene)malononitrile(cas: 75629-62-8).SDS of cas: 75629-62-8

The Article related to diheteroarylmethane preparation, methane diheteroaryl preparation, nitrile condensation cyclization, Heterocyclic Compounds (More Than One Hetero Atom): General and other aspects.SDS of cas: 75629-62-8

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts