On January 30, 2004, Yadav, Jhillu S.; Reddy, Basi V. Subba; Basak, Ashok K.; Visali, Boddapati; Narsaiah, Akkirala Venkat; Nagaiah, Kommu published an article.COA of Formula: C12H7N3 The title of the article was Phosphane-catalyzed Knoevenagel condensation: A facile synthesis of 伪-cyanoacrylates and 伪-cyanoacrylonitriles. And the article contained the following:
Triphenylphosphane has been utilized as an efficient catalyst for the Knoevenagel condensation of aldehydes with acidic methylene compounds such as Et cyanoacetate and malononitrile to afford substituted olefins, e.g., I. The reaction proceeded smoothly under solvent-free conditions and the products were obtained in excellent yields with an E-geometry. This method was applied to a wide range of aldehydes including aromatic, aliphatic and heterocyclic substrates. Microwave irradiation has been used to achieve enhanced reaction rates and improved yields. The experimental process involved the reaction of 2-((1H-Indol-3-yl)methylene)malononitrile(cas: 75629-62-8).COA of Formula: C12H7N3
The Article related to arylaldehyde cyanoacetate knoevenagel condensation, arylidene cyanoacetate stereoselective preparation, phosphane knoevenagel condensation catalyst, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Nitriles, Isonitriles, and Acyl Cyanides and other aspects.COA of Formula: C12H7N3
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts