Alizadeh, Abdolali; Sedighian, Hadi; Yasub Hosseini, Seyed; Zhu, Long-Guan published an article in 2015, the title of the article was Synthesis of Polysubstituted Benzenes via the Vinylogous Michael Addition of Alkylidenemalononitriles to 2-(1,3-Dioxo-1H-inden-2(3H)-ylidene)malononitrile.Product Details of 2510-01-2 And the article contains the following content:
An efficient synthesis for polysubstituted benzenes I [R1 = H; R1R2 = CH2CH2CH2, CH2CH2CH2CH2, etc.; R2 = C6H5, 4-H3CC6H4, chromen-2-one-3yl, etc.; R3 = CH3, CH2CH3] were successfully developed by the reaction of ninhydrin (2,2-dihydroxyindane-1,3-dione), malononitrile (propanedinitrile) and alkylidenemalononitrile. The method involves vinylogous Michael addition of alkylidenemalononitrile to 2-(1,3-dioxo-1H-inden-2(3H)-ylidene)malononitrile, which formed by condensation of malononitrile and ninhydrin in the presence of Et3N, and the alc. solvent has participated in the reaction as a reagent. The method has the advantages of good yields and of not requiring a metal catalyst. The structures were confirmed spectroscopically and in the case of compound I [R1R2 = -CH2CH2CH2CH2-; R3 = CH3], by X-ray crystallog. A plausible mechanism for this reaction is proposed. The experimental process involved the reaction of 2-(2,3-Dihydro-1H-inden-1-ylidene)malononitrile(cas: 2510-01-2).Product Details of 2510-01-2
The Article related to malononitrile ninhydrin condensation triethylamine catalyst, dioxo indenylidene malononitrile preparation alkylidenemalononitrile vinylogous michael addition, polysubstituted benzene preparation and other aspects.Product Details of 2510-01-2
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts