Nitrile is any organic compound with a −C≡N functional group. 31643-49-9, formula is C8H3N3O2, Name is 4-Nitrophthalonitrile.The prefix cyano- is used interchangeably with the term nitrile in literature. Safety of 4-Nitrophthalonitrile.
Yuzeroglu, Murat;Keser Karaoglan, Gulnur;Gumrukcu Kose, Gulsah;Erdogmus, Ali research published 《 Synthesis of new zinc phthalocyanines including schiff base and halogen; photophysical, photochemical, and fluorescence quenching studies》, the research content is summarized as follows. This study reports a series of new sym. tetra substituted zinc phthalocyanines namely {2,9,16,23-Tetra-(4-[4-{[(1E)-(4-fluorophenyl)methylene]amino}phenoxy])-phthalocyaninato} zinc(II) (7), {2,9,16,23-Tetra-(4-[4-{[(1E)-(4-chlorophenyl)methylene]amino}phenoxy])-phthalocyaninato}zinc(II) (8), and {2,9,16,23-Tetra-(4-[4-{[(1E)-(4-bromophenyl)methylene] amino}phenoxy])- phthalocyaninato}zinc(II) (9). The resulting macromols. were characterized using some spectroscopic methods consisting of UV-Vis, FT-IR, 1H NMR, and MALDI-TOF MS spectroscopy, together with elemental anal. The photophysicochem. features of the newly synthesized phthalocyanines includiing fluorescence, photodegradation, and singlet oxygen quantum yields were studied in different solvents such as DMF, DMSO, and THF to explore their potential as suitable photosesitizers. Solvent effect on the photophys. and photochem. parameters of the tetra-substituted phthalocyanines bearing the 4-{[(1E)-(4-fluorophenyl)methylene]amino}phenoxy, 4-{[(1E)-(4-chlorophenyl)methylene]amino}phenoxy, 4-{[(1E)-(4-bromophenyl)methylene]amino}phen-oxy groups were investigated, as well. In comparison to the known Schiff base containing phthalocyanines, the newly synthesized compounds exhibited higher singlet oxygen values. Singlet oxygen yields of the complexes (7–9) were obtained between 0.57 and 0.86. Due to the high singlet oxygen yields of compounds (7–9), they can be listed as photosensitizers in the implementation of photocatalytic applications such as photodynamic therapy (PDT) which is an efficient method for the treatment of cancer.
31643-49-9, 4-Nitrophthalonitrile, also known as 4-Nitrophthalonitrile, is a useful research compound. Its molecular formula is C8H3N3O2 and its molecular weight is 173.13 g/mol. The purity is usually > 95%.
4-Nitrophthalonitrile is a chemical substance that can be synthesized by the reaction of sodium carbonate with 3,4,5-trimethoxybenzyl alcohol. It can also be prepared using nitro phenol and sodium hydroxide. 4-Nitrophthalonitrile has been shown to have high photochemical activity in the presence of light. The frequency shift of its infrared spectrum is indicative of a nucleophilic addition reaction mechanism. 4-Nitrophthalonitrile has been used as an intermediate for producing other chemicals, such as herbicides and pharmaceuticals., Safety of 4-Nitrophthalonitrile
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts