Nitriles are found in many useful compounds. Nitrile rubber is also widely used as automotive and other seals since it is resistant to fuels and oils. Organic compounds containing multiple nitrile groups are known as cyanocarbons. 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Nitriles are found in many useful compounds. One of the most common occurrences of nitriles is in Nitrile rubber. Quality Control of 3032-92-6.
Wang, Fu-Li;Yang, Chang-Jiang;Liu, Ji-Ren;Yang, Ning-Yuan;Dong, Xiao-Yang;Jiang, Ruo-Qi;Chang, Xiao-Yong;Li, Zhong-Liang;Xu, Guo-Xiong;Yuan, Dai-Lei;Zhang, Yu-Shuai;Gu, Qiang-Shuai;Hong, Xin;Liu, Xin-Yuan research published 《 Mechanism-based ligand design for copper-catalysed enantioconvergent C(sp3)-C(sp) cross-coupling of tertiary electrophiles with alkynes》, the research content is summarized as follows. A general copper-catalyzed enantioconvergent C(sp3)-C(sp) cross-coupling of diverse racemic tertiary alkyl halides RX [R = 1-cyclohexyl-1-[(naphthalen-1-yl)carbamoyl]ethyl, 1-phenyl-1-(phenylcarbamoyl)propyl, 1-[(4-bromophenyl)carbamoyl]-1-phenylpropyl, etc.; X = Cl, Br] and I (R1 = Et, cyclopropyl, benzyl, etc.; R2 = Et, Ph, 3-bromophenyl, etc.) with terminal alkynes R3CCH (R3 = Ph, cyclohexen-1-yl, thiophen-2-yl, etc.) (87 examples) was demonstrated. Key to the success is the rational design of chiral anionic N,N,N-ligands, e.g., II (R4 = t-butylphenyl) tailor-made for the computationally predicted outer-sphere radical group transfer pathway. This protocol provides a practical platform for the construction of chiral C(sp3)-C(sp/sp2/sp3) bonds, allowing for expedient access to an array of synthetically challenging quaternary carbon building blocks of interest in organic synthesis and related areas.
Quality Control of 3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.
4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., 3032-92-6.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts