Nitriles are found in many useful compounds. Nitrile rubber is also widely used as automotive and other seals since it is resistant to fuels and oils. Organic compounds containing multiple nitrile groups are known as cyanocarbons. 1835-49-0, formula is C8F4N2, Name is Tetrafluoroterephthalonitrile. Nitriles are found in many useful compounds. One of the most common occurrences of nitriles is in Nitrile rubber. Name: Tetrafluoroterephthalonitrile.
Luo, Da-Yun;Hu, Xing-Mei;Huang, Rong;Cui, Shi-Sheng;Yan, Sheng-Jiao research published 《 Base-promoted relay reaction of heterocyclic ketene aminals with o-difluorobenzene derivatives for the highly site-selective synthesis of functionalized indoles》, the research content is summarized as follows. A novel method was developed for the construction of highly functionalized indole derivatives, including fluorinated indoles I (R = H, F, CN, NO2; R1 = H, F, NO2, CN; R2 = H, F, methoxycarbonyl; R3 = H, F CN; R4 = NO2, benzoyl, (4-chlorophenyl)carbonyl, (thiophen-2-yl)carbonyl, etc.; Z = CH, N), via a site-selective, one-pot, two-step nucleophilic aromatic substitution reaction of o-difluorobenzene derivatives II with heterocyclic ketene aminals (HKAs) III promoted by two different bases (K2CO3 and Cs2CO3). A diverse library of indoles I was generated in good to excellent yields using a conventional base-mediated approach rather than metal catalysts. As a result, the highly functionalized indoles I were easily obtained in an environmentally friendly, rapid, and practical manner, and the products have potential biol. activity.
1835-49-0, Tetrafluoroterephthalonitrile can react with alkyl grignard reagents to form 4-alkyltetraflurorobenzonitriles. It acts as a four electron donor ligand. Tetrafluoroterephthalonitrile can be used to synthesize polymers of intrinsic microporosity. It has been used to study UV rearranged polymers of teh PIM-1 type membrane for the efficient separation of H2 and CO2.
Tetrafluoroterephthalonitrile reacts with alkyl Grignard reagents to form corresponding 4-alkyltetrafluorobenzonitriles. Tetrafluoroterephthalonitrile acts as a four-electron donor ligand and forms tungsten(II)η 2-nitrile complexes.
Tetrafluoroterephthalonitrile is a hydroxyl group-containing organic chemical compound . It has been used in analytical chemistry as a reagent for the determination of peptide binding constants and disulfide bonds. Tetrafluoroterephthalonitrile binds to nucleophilic sites on proteins, such as the pim-1 protein, and can be used to transport other molecules across cell membranes. In addition, it has been used to produce polymers for use in analytical chemistry. This chemical is also able to bind with magnetic particles under constant pressure conditions, which makes it useful for optical sensor applications. , Name: Tetrafluoroterephthalonitrile
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts