In 2019,Inorganic Chemistry included an article by Hiscock, Lana K.; Joekar, Delara; Balonova, Barbora; Tomas Piqueras, Marta; Schroeder, Zachary W.; Jarvis, Victoria; Maly, Kenneth E.; Blight, Barry A.; Dawe, Louise N.. HPLC of Formula: 614-16-4. The article was titled 《Structures, Phase Behavior, and Fluorescent Properties of 3-Phenyl-1-(pyridin-2-yl)-1H-pyrazol-5-amine and Its ZnCl2 Complex》. The information in the text is summarized as follows:
The synthesis of the asym. ligand 3-phenyl-1-(pyridin-2-yl)-1H-pyrazol-5-amine (L1) and its single-crystal X-ray structure are reported. L1 displays crystallog. symmetry (orthorhombic, Pccn) higher than its mol. symmetry (point group C1) and also displays supercooling, with a difference in the melting and solidification points of over 100°C. Upon complexation with ZnCl2, L1 engages in both primary cation and secondary anion coordination via hydrogen bonding, and the complex exhibits a room-to-low-temperature single crystal-to-crystal phase transition. The ZnCl2 complex becomes a birefringent fluid mixed with crystalline domains at high temperatures, as detected by polarized optical microscopy. Examination of the photoluminescence properties showed that the emission intensity increased and a pronounced bathochromic shift was observed in the emission maximum upon going from solution to the solid state, for both the ligand and complex, consistent with aggregation-induced emission behavior. The syntheses and single-crystal structures of 3-phenyl-1-(pyridin-2-yl)-1H-pyrazol-5-amine (L1) and its complex with ZnCl2 are reported. L1 exhibits supercooling, with a difference in the melting and solidification points of over 100°C. The complex [L1ZnCl2] has a room-to-low-temperature single crystal-to-crystal phase transition in the solid state, while a birefringent fluid phase mixed with crystalline domains is present at high temperatures Significant fluorescence enhancement is observed upon formation of the ZnCl2 complex. The experimental part of the paper was very detailed, including the reaction process of 3-Oxo-3-phenylpropanenitrile(cas: 614-16-4HPLC of Formula: 614-16-4)
3-Oxo-3-phenylpropanenitrile(cas: 614-16-4) has been used to produce 2-benzoyl-3-furan-2-yl-acrylonitrile. It is an active methylene compound, useful in heterocyclic synthesis, e.g. polyfunctional pyridines and pyrimidines.HPLC of Formula: 614-16-4
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts