Prieto, Auxiliadora; Halland, Nis; Jorgensen, Karl Anker published the artcile< Novel Imidazolidine-Tetrazole Organocatalyst for Asymmetric Conjugate Addition of Nitroalkanes>, Quality Control of 6136-93-2, the main research area is asym Michael addition nitroalkane unsaturated enone; chiral imidazolidinyltetrazole asym Michael addition catalyst.
The Michael addition of nitroalkanes to α,β-unsaturated enones catalyzed by a novel chiral imidazolidin-2-yltetrazole organocatalyst (I) has been investigated. The new more soluble organocatalyst decreases reaction times and improves enantioselectivities compared to other catalysts. The Michael addition adducts were obtained with up to 92% ee. E.g., addition of Me2CHNO2 to PhCH:CHCOMe in presence of I gave 97% nitro ketone II.
Organic Letters published new progress about Alkanes, nitro Role: RCT (Reactant), RACT (Reactant or Reagent). 6136-93-2 belongs to class nitriles-buliding-blocks, and the molecular formula is C6H11NO2, Quality Control of 6136-93-2.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts