《Hypervalent Iodine(III)-Catalysed Enantioselective α-Acetoxylation of Ketones》 was published in Chemistry – A European Journal in 2020. These research results belong to Hokamp, Tobias; Wirth, Thomas. Electric Literature of C9H7NO The article mentions the following:
An enantioselective catalytic synthesis of α-acetoxylated ketones through I(I)/I(III) catalysis using a resorcinol/lactamide-based chiral iodoarene was reported. Catalyst turnover by in-situ generation of the active iodine(III) derivative was achieved by oxidation with mCPBA in the presence of acetic acid. The prior transformation of ketones to easily accessible acetyl enol ethers was beneficial and yields up to 97% with enantioselectivities up to 88% ee were obtained using only low catalyst loadings of only 5 mol % under mild reaction conditions. In the experiment, the researchers used many compounds, for example, 3-Oxo-3-phenylpropanenitrile(cas: 614-16-4Electric Literature of C9H7NO)
3-Oxo-3-phenylpropanenitrile(cas: 614-16-4) has been used to produce 2-benzoyl-3-furan-2-yl-acrylonitrile. It is an active methylene compound, useful in heterocyclic synthesis, e.g. polyfunctional pyridines and pyrimidines.Electric Literature of C9H7NO
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts