Wei, Yueting; Liu, Ping; Liu, Yali; He, Jing; Li, Xuezhen; Li, Shiwu; Zhao, Jixing published their research in Organic & Biomolecular Chemistry in 2021. The article was titled 《NIS-promoted three-component reaction of 3-oxo-3-arylpropanenitriles with arylsulfonyl hydrazides》.Related Products of 614-16-4 The article contains the following contents:
A new three-component reaction of 3-oxo-3-arylpropanenitriles with arylsulfonyl hydrazides was established and an expanded inventory of 3-aryl-4-(arylthio)-1H-pyrazol-5-amines were synthesized by sequential cyclization and sulfenylation reactions under the action of NIS. In addition to the attractive features of multicomponent reactions, the protocol presented broad substrate scope, good functional group tolerance and mild reaction conditions. The utility of this procedure was further established by gram-scale synthesis as well as the diversified transformations of the products to useful compounds After reading the article, we found that the author used 3-Oxo-3-phenylpropanenitrile(cas: 614-16-4Related Products of 614-16-4)
3-Oxo-3-phenylpropanenitrile(cas: 614-16-4) has been used to produce 2-benzoyl-3-furan-2-yl-acrylonitrile. It is an active methylene compound, useful in heterocyclic synthesis, e.g. polyfunctional pyridines and pyrimidines.Related Products of 614-16-4
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts