Inami, Kaoru; Shiba, Tetsuo published the artcile< Total synthesis of antibiotic althiomycin>, HPLC of Formula: 6136-93-2, the main research area is total synthesis althiomycin antibiotic.
Total synthesis of antibiotic althiomycin (I) was achieved staring from D-cysteine. The imide bond between thiazoline and the pyrrolinone part was constructed by coupling reaction of sodium salt of pyrrolinone with cysteine active ester or by photoreaction with diketene. The hydroxymethyl group attached on the carbon adjacent to C-2 of the thiazoline ring, was introduced by aldol condensation posterior to the thiazoline ring formation. The thiazole part was introduced in a final step in whole process of the total synthesis of the antibiotic. The synthetic althiomycin was identical with the natural antibiotic in all respects.
Bulletin of the Chemical Society of Japan published new progress about 6136-93-2. 6136-93-2 belongs to class nitriles-buliding-blocks, and the molecular formula is C6H11NO2, HPLC of Formula: 6136-93-2.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts