Schmittling, Elisabeth A.; Sawyer, J. Scott published the artcile< Synthesis of diaryl ethers, diaryl thioethers, and diarylamines mediated by potassium fluoride-alumina and 18-crown-6>, Synthetic Route of 94087-40-8, the main research area is coupling phenol benzonitrile; Ullmann phenol benzonitrile crown potassium fluoride; ether synthesis phenol thiophenol benzonitrile; aniline coupling benzonitrile; phenylamine preparation; phenyl sulfide preparation; thioether biaryl preparation; biarylamine preparation.
An efficient alternative to the copper-catalyzed synthesis (Ullmann ether synthesis) of biaryl ethers, biaryl thioethers, and biaryl amines involving the potassium fluoride-alumina-mediated addition of a phenol, thiophenol, or an aniline to 2- or 4-fluorobenzonitriles catalyzed by 18-crown-6 is described. An efficient alternative to the copper-catalyzed synthesis (Ullmann ether synthesis) of biaryl ethers, biaryl thioethers, and biaryl amines involving the potassium fluoride-alumina-mediated addition of a phenol, thiophenol, or an aniline to 2- or 4-fluorobenzonitriles catalyzed by 18-crown-6 is described.
Journal of Organic Chemistry published new progress about Aromatic ethers Role: SPN (Synthetic Preparation), PREP (Preparation). 94087-40-8 belongs to class nitriles-buliding-blocks, and the molecular formula is C7H3ClFN, Synthetic Route of 94087-40-8.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts