In 2013,Lee, Sunggi; Lee, Hyelee; Tan, Kian L. published 《Meta-Selective C-H Functionalization Using a Nitrile-Based Directing Group and Cleavable Si-Tether》.Journal of the American Chemical Society published the findings.Recommanded Product: 31938-07-5 The information in the text is summarized as follows:
A nitrile-based template that enables meta-selective C-H bond alkenylation of benzylic alcs. was developed. The template is applicable to a range of substituted arenes and tolerates a variety of functional groups. The directing group uses a silicon atom for attachment, allowing for a facile introduction/deprotection strategy increasing the synthetic practicality of this template. In the experimental materials used by the author, we found 2-(3-Bromophenyl)acetonitrile(cas: 31938-07-5Recommanded Product: 31938-07-5)
2-(3-Bromophenyl)acetonitrile(cas: 31938-07-5) has been used in the synthesis of 2-(1-cyano-1-(3-bromophenyl))methylidene-3-phenylthiazolidine-4,5-dione or a series of aminoethylbiphenyls, novel 5-HT7 receptor ligands.Recommanded Product: 31938-07-5
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts