The author of 《An Eco-friendly Synthesis and Biological Screening of Fused Heterocyclic Compounds Containing a Thiophene Moiety via Gewald Reaction》 were El-Borai, Mohamed A.; Rizk, Hala F.; Ibrahim, Seham A.; Fares, Amira K.. And the article was published in Journal of Heterocyclic Chemistry in 2019. Recommanded Product: 3-Oxo-3-phenylpropanenitrile The author mentioned the following in the article:
5-Amino-3-phenyl-1-(2,4,6-trichlorophenyl)-1H-thieno[3,2-c]pyrazole-6-carbonitrile was designed and synthesized by one-pot multicomponent reaction. Compound 5-amino-3-phenyl-1-(2,4,6-trichlorophenyl)-1H-thieno[3,2-c]pyrazole-6-carbonitrile was reacted with different reagents to obtain new condensed moieties with our thienopyrazole skeleton. The compounds e.g., I were prepared by using environmentally benign techniques as microwave irradiation, ultrasonic irradiation and ball-milling. The new compounds e.g., I were evaluated for their in vitro antibacterial and antifungal potentialities. In the experiment, the researchers used many compounds, for example, 3-Oxo-3-phenylpropanenitrile(cas: 614-16-4Recommanded Product: 3-Oxo-3-phenylpropanenitrile)
3-Oxo-3-phenylpropanenitrile(cas: 614-16-4) has been used to produce 2-benzoyl-3-furan-2-yl-acrylonitrile. It is an active methylene compound, useful in heterocyclic synthesis, e.g. polyfunctional pyridines and pyrimidines.Recommanded Product: 3-Oxo-3-phenylpropanenitrile
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts