Zafari, Parvin; Saatluo, Bahman Ebrahimi; Rashidi, Ahmad; Baradarani, Mehdi M.; Joule, John A. published their research in ARKIVOC (Gainesville, FL, United States) in 2021. The article was titled 《Three-component synthesis of novel spiro[4H-pyran-3,3′-oxindoles] using 5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinoline-1,2-dione》.SDS of cas: 614-16-4 The article contains the following contents:
One-pot, three-component reactions of the tricyclic isatin 5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinoline-1,2-dione with variously substituted aryl cyanomethyl ketones and malononitrile, or Et cyanoacetate, generated spiro[4H-pyran-3,3′-oxindoles] I [X = CN, COOEt; R = H, 4-Me, 4-Cl, etc.] such as, 2-amino-2′-oxo-6-(phenyl)-5′,6′-dihydro-2’H,4’H-spiro[pyran-4,1′-pyrrolo[3,2,1-ij]quinoline]-3,5-dicarbonitrile. The experimental part of the paper was very detailed, including the reaction process of 3-Oxo-3-phenylpropanenitrile(cas: 614-16-4SDS of cas: 614-16-4)
3-Oxo-3-phenylpropanenitrile(cas: 614-16-4) has been used to produce 2-benzoyl-3-furan-2-yl-acrylonitrile. It is an active methylene compound, useful in heterocyclic synthesis, e.g. polyfunctional pyridines and pyrimidines.SDS of cas: 614-16-4
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts