Shiba, Tetsuo’s team published research in Heterocycles in 1979-12-30 | 6136-93-2

Heterocycles published new progress about Configuration. 6136-93-2 belongs to class nitriles-buliding-blocks, and the molecular formula is C6H11NO2, Application of C6H11NO2.

Shiba, Tetsuo; Inami, Kaoru; Sawada, Kozo; Hirotsu, Yoshihiro published the artcile< Synthesis and geometric configuration of 2-(hydroxyiminomethyl)thiazole-4-carboxylic acid in antibiotic althiomycin>, Application of C6H11NO2, the main research area is althiomycin configuration; hydroxyiminomethylthiazole preparation configuration.

Isomeric oximes I (R = Et) were prepared from (EtO)2CHCO2Et in 6 steps. The isomers were separated and their configuration determined by nuclear Overhauser enhancement. These assignments were used to established that I (R = H) in althiomycin have the syn configuration and it isomerized on purification on acid ion exchange resin. Althiomycin has the syn configuration II.

Heterocycles published new progress about Configuration. 6136-93-2 belongs to class nitriles-buliding-blocks, and the molecular formula is C6H11NO2, Application of C6H11NO2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts