In 2022,Kunj M. Trivedi; Patel, Unnati P.; Dabhi, Ranjit C.; Maru, Jayesh J. published an article in Russian Journal of Bioorganic Chemistry. The title of the article was 《Synthesis, Computational Insights and Anticancer Activity of Novel Indole-Schiff Base Derivatives》.Name: 4-Cyanobenzyl bromide The author mentioned the following in the article:
This paper described computational insights and synthesis of novel indole clubbed Schiff base derivatives I [R = Ph, 3-pyridyl, 4-MeC6H4, etc.] with improved biol. profile. The prepared derivatives I were evaluated for their in vitro anticancer activity against A549 cell line using MTT assay. Results revealed significant potential of the synthesized compounds, especially I [R = 2-furyl] which exhibited high anticancer activity. The experimental part of the paper was very detailed, including the reaction process of 4-Cyanobenzyl bromide(cas: 17201-43-3Name: 4-Cyanobenzyl bromide)
4-Cyanobenzyl bromide(cas: 17201-43-3) is a white solid. Its melting point is 113-117°C, and flash point is 125.1°C. It is insoluble in water at 20°C. It is stable under normal temperatures and pressures. It should be stored at 0-5°C.Name: 4-Cyanobenzyl bromide
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts