Chen, Weiqiang; Yang, Qin; Zhou, Tian; Tian, Qingshan; Zhang, Guozhu published the artcile< Enantioselective Synthesis of α-exo-Methylene γ-Butyrolactones via Chromium Catalysis>, SDS of cas: 94087-40-8, the main research area is aldehyde ethyl acrylate bromomethyl chromium allylation alkoxycarbonyl lactonization catalyst; butyrolactone methylene stereoselective preparation.
Enantioenriched α-exo-methylene γ-butyrolactones I [R = (CH2)2Ph, cyclohexyl, n-hexyl, cyclopropyl, Ph, 4-BrC6H4, 2-thienyl, etc.] have been obtained via a two-step sequence consisting of a highly enantioselective chromium-catalyzed carbonyl 2-(alkoxycarbonyl)allylation and lactonization. A variety of functional groups are compatible under the mild reaction conditions. The synthetic utility of this methodol. was demonstrated by two short derivatization transformations and the enantioselective synthesis of (+)-methylenolactocin.
Organic Letters published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 94087-40-8 belongs to class nitriles-buliding-blocks, and the molecular formula is C7H3ClFN, SDS of cas: 94087-40-8.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts