In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Hybrid phase ligation for efficient synthesis of histone proteins, published in 2016, which mentions a compound: 117918-23-7, mainly applied to histone protein synthesis hybrid phase ligation refolding; solid phase peptide synthesis NCL desulfurization, COA of Formula: C11H19NO4S.
We introduce a hybrid solid-solution phase ligation approach that combines the efficiency of solid phase ligation with solution phase ligation in the total synthesis of modified histone proteins. A two linker strategy allows anal. throughout work on the solid phase and maximizes yields through cleavage at an external Rink, while an internal HMBA linker allows the native carboxyl terminus for any protein sequence. We demonstrate this approach for two histone proteins: triple-acetylated H4, K5ac, K12ac, K91ac, and CENP-A-K124ac.
I hope my short article helps more people learn about this compound((R)-3-(tert-Butoxycarbonyl)-5,5-dimethylthiazolidine-4-carboxylic acid)COA of Formula: C11H19NO4S. Apart from the compound(117918-23-7), you can read my other articles to know other related compounds.
Reference:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts